N/A N=60 Dysregulation of FSH in Obesity: Functional and Statistical Analysis
Obesity · Fertility
Primary: Difference Between Peak Inhibin B — 100.8; 38.8 picograms/mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=379 Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility
Infertility, Female
Primary: Rate of Good Birth Outcomes — 23; 29 Participants — p=0.404
N/A N=120 Endometrial Injury for Unexplained Infertility
Infertility
Primary: Measurement of Uterine Artery Pulsatility Index — 2.40; 2.35 index — p=<0.05
N/A N=114 Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility Unexplained · Infertility, Male · DNA Damage
Primary: DNA Fragmentation as a Predictor of Live Birth Rate — 32 Participants — p=0.04
N/A N=62 Reproductive Hormonal Alterations in Obesity
Obesity
Primary: Changes in Luteinizing Hormone (LH) Pulse Amplitude (Aim 1) — 4.1; 3.6 IU/L
N/A N=88 Anti-Helicobacter Pylori Antibodies (IgG) in Serum of Women With Unexplained Infertility
Infertility, Female
Primary: Quantitative Helicobacter Pylori IgG Assay in Serum — 70; 70 arbitrary unit per millilitre — p=<0.001
Early Phase 1 N=6 Investigation of Female Reproductive Hormone Dynamics During Adolescence
Menstruation Disturbances
Primary: Ovulation in Cycle 2 — 3; 2 Participants
Phase 2 N=10 Elagolix for Fertility Enhancement Clinical Trial
Endometriosis · Unexplained Infertility
Primary: Number of Live Births — 3; 1 live births
N/A N=26 Pharmacogenetics of Metformin Action in PCOS
Polycystic Ovary Syndrome
Primary: Number of Responders/Non-responders for Each STK11 rs8111699 Genotype (C/G, C/C, G/G) — 6; 7; 5; 3 participants
Phase 2 N=149 Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) Women
Polycystic Ovary Syndrome
Primary: Live Birth Rate — 13; 5; 12 participants — p=0.06
N/A N=49 Feasibility Study for Development of an Early Test for Ovarian Failure
Healthy · Premature Ovarian Failure
Primary: Follicle Stimulating Hormone Stimulated Serum Inhibin B Levels. — 50.7; 48.8; 96.6; 47.7 participants
N/A N=20 Differential Effects of Clomiphene Citrate in Women Undergoing Superovulation
Mood
Primary: Follicular Cycle Total Behavioral Score for Calendar of Premenstrual Experiences (COPE) Self Assessment — 3; 5 units on a scale
Phase 2 N=520 Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)
Infertility
Primary: Number of Fertilized Oocytes (2 Pronuclei [PN]) — 7.0; 8.7; 9.2; 6.7 2PN oocytes
Phase 3 N=1,031 A Multicenter Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Intravaginal Micronized Progesterone Capsules 600 mg Daily for Luteal Support in In-Vitro Fertilization
Female Infertility
Primary: Percentage of Participants Being Pregnant as Measured by the Presence of Fetal Heart Beats at 12 Weeks´Gestation Using Transvaginal Ultrasound — 37.6; 33.1 percentage of…
N/A N=70 Intrauterine Environment in Polycystic Ovary Syndrome (PCOS) Probands
Polycystic Ovary Syndrome
Primary: Estradiol Level in Female Offspring — 18606; 6467 pg/ml — p=0.049
Phase 2 N=41 Assessing the Endometrial Environment in Recurrent Pregnancy Loss and Unexplained Infertility
Recurrent Pregnancy Loss · Unexplained Infertility
Primary: Abnormal Microbiome Bacterial Sequencing
Phase 4 N=23 Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study
Infertility
Primary: Oocytes — 19; 47 oocytes
Early Phase 1 N=100 Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS
Polycystic Ovary Syndrome · Infertility
Primary: Ovulation Rate — 93; 108 percentage of all cycles
N/A N=97 The Impact of Distress on the IVF Outcome
Infertility
Primary: Clinical Pregnancy Rates — 20; 52 percentage of participants
N/A N=39 Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
Obesity · Fertility
Primary: Change in the Average LH Pulse Amplitude — -.04; .4 IU/L
Phase 3 N=265 SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Infertility · Ovulation Induction
Primary: Percentage of Participants With Ovulation — 79.1; 82.6 percentage of participants
Phase 1 N=34 Bioequivalence Trial of Liquid Versus Freeze-Dried Pergoveris® in Pituitary Suppressed Healthy Premenopausal Female Subjects
Healthy
Primary: Baseline Corrected Area Under the Concentration-Time Curve From Zero to Last Quantifiable Concentration (AUC 0-t,Adj) for Follicle-Stimulating Hormone (FSH) — 3187.4…
N/A N=42 Sildenafil Vaginal Gel Co-treatment With Clomiphene Citrate in Infertile Women With Thin Endometrium
Anovulation
Primary: Endometrial Thickness — 6.6; 9.3 millimeter
Phase 3 N=900 Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
Pregnancy · Unexplained Infertility
Primary: Multiple Gestation Rate Following Recruitment of Multiple Follicular Development With an AI, as Compared to CC and FSH. — 9; 8; 34 number of multiples
Phase 4 N=70 Combined Letrozole and Clomid in Women With Infertility and PCOS
Polycystic Ovary Syndrome · Infertility
Primary: Number of Participants Achieving Ovulation Measured by Mid-luteal Progesterone Level — 15; 27 Participants — p=0.007
Phase 4 N=90 Effects of Intrauterine Flushing With Human Chorionic Gonadotropin on ICSI Outcome
Female Infertility
Primary: Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer — 43.56; 41.59; 40.94; 30.33 pg/ml
Phase 4 N=442 Predictive Factors for Ovarian Stimulation Using a Fixed Daily Dose of 200 IU Recombinant FSH (Study 142003)(P05696)
Infertility
Primary: Total Number of Oocytes — 12.4; 12.1 Number of oocytes
Phase 4 N=15 Effect of hCG on Receptivity of the Human Endometrium
Infertility · Subfertility
Primary: Endometrial Staging in hCG Versus Vehicle Treated Patients — 4.0; 4.6; 3.9; 6.5 days — p=<0.05
N/A N=93 Reproductive Outcome Affected by Two Adjunctive Treatments in Patients With Severe Intrauterine Adhesions
Asherman's Syndrome
Primary: Number of Participants With Pregnancy in Loop-shaped Intrauterine Device Group and Intrauterine Balloon Group — 12; 22 participants — p=0.009
Phase 2 N=271 Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertile Women With Ovulatory Dysfunction
Anovulation
Primary: Ovulation Rate in Cycle 1 — 64.9; 30.4; 36.8; 35.9 percentage of subjects