N/A N=80 Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Post Operative Pain · Recurrence
Primary: Number of Participants With Recurrence of Disease or Fistula — 5; 10 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=63 Idiopathic Hypertensive Anal Canal: a Place of Internal Sphincterotomy
Hypertensive Anal Canal
Primary: Effect of Closed Lateral Sphincterotomy and Chemical Sphincterotomy on Hypertensive Anal Canal
Phase 3 N=248 A Study to Determine the Effect of Nitroglycerin Ointment 0.4% (Cellegesic) on the Pain Associated With Chronic Anal Fissures
Fissure in Ano · Pain
Primary: Change From Baseline in Pain Intensity at Days 14-18 — -40.4; -34.9 Units on a scale
Phase 3 N=465 Diltiazem Hydrochloride Cream for Anal Fissure
Chronic Anal Fissure
Primary: Change From Baseline in Average of Worst Anal Pain Associated With or Following Defaecation for Week 4 (for the 7 Treatment Days Immediately Preceding the Week 4 Visit)…
N/A N=20 The Use of an "Anal-Tape" in Patients With Fecal Incontinence
Fecal Incontinence
Primary: Any Improvment in the Fecal Incontince Quality of Life Scale (FIQoLs) — 2.8; 3.3; 1.9; 2.5 score on a scale
N/A N=86 A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas
Anal Fistula
Primary: Healing Success — 22; 25 participants — p=0.59
N/A N=200 Fecal Incontinence Treatment (FIT) Study
Fecal Incontinence · Bowel Incontinence
Primary: Treatment Response Defined as a 75% or Greater Change in Number of Average Weekly FI Episodes at Month 3 Follow-Up Compared to Baseline — 29; 28 Participants
N/A N=1,718 Prevalence and Treatment of Anal Incontinence (AI) in Primiparous Women
Fecal Incontinence
Primary: Change in Anal Incontinence as Measured on the St. Mark's Score — 4.3; 4.5; 3.6; 4.1 units on a scale
N/A N=10 A Safety and Tolerability of Circumferential Anal Canal Radiofrequency Ablation For Anal Intraepithelial Neoplasia
Anal Intraepithelial Neoplasia (AIN) · High-grade Squamous Intraepithelial Lesions (HSIL)
Primary: Related Adverse Events — 1; 1 number of participants
N/A N=100 A Prospective, Multi-center, Observational Study of the Use of Permacol™ Collagen Paste to Treat Anorectal Fistulas
Anorectal Fistulas
Primary: Fistula Healing in Patients at 6 Months Following Surgery — 56.7; 43.3 percentage of participants
N/A N=124 Effects of an Anal Insert Device in Fecal Incontinence
Fecal Incontinence
Primary: Primary Effectiveness Endpoint — 75.9 percentage of treatment responders
N/A N=120 Sacral Nerve Stimulation Therapy for the Treatment of Chronic Fecal Incontinence
Fecal Incontinence
Primary: Proportion of Subjects With at Least 50% Reduction in Number of Incontinent Episodes Per Week — 0.73 proportion of subjects — p=<0.0001
N/A N=3,032 Perianal Fistula (PAF) Validation and Burden of Illness Study
Inflammatory Bowel Disease · Perianal Fistula · Crohns Disease
Primary: Objective 1: Number of CD Participants Who Have CPAF Using Various Codes in an TOH Database — 120; 120; 127; 127 Participants
N/A N=35 Feasibility Study of the Magnetic Anal Sphincter (FENIX System)
Fecal Incontinence
Primary: Adverse Events — 223; 7 Number of events
N/A N=300 War-Drill Model Guided Treatment of Hemorrhoids With Nimsai Herbal (NAJ)
Hemorrhoids · Hemorrhoidal Disease
Primary: Hemorrhoid Regression Rate — 117; 33 Participants — p=<0.001
N/A N=31 Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Pelvic Floor Disorders
Primary: Opening Pressure — 56.35; 39.01; 23.42 cmH20
N/A N=52 Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
Obstructed Defecation Syndrome · Rectocele · Intussusception
Primary: Quality of Life — 3.2; 3.7; 2.8; 3.3 units on a scale — p=0.1340
N/A N=36 Evaluation of the Fast Fill Technique for Anal Acoustic Reflectometry (AAR) in the Incontinent Anal Sphincter
Faecal Incontinence
Primary: Opening Pressure — 35.13; 37.5 cmH2O
Phase 2 N=53 Autologous Cell Therapy for Treatment of Fecal Incontinence
Fecal Incontinence
Primary: Number of Treatment-Related Adverse Events — 0; 1; 5; 28 events
N/A N=26 Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
Inflammatory Bowel Disease · Perianal Fistula · Perianal Abscess
Primary: Prevalence of Inflammation as Diagnosed by Capsule Endoscopy — 6 participants
N/A N=40 Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry
Pelvic Floor Dysfunction
Primary: Opening Pressure — 34.44; 15.41 cmH2O
Phase 3 N=150 Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula
Crohn's Disease · Complex Perianal Fistula
Primary: Number of Participants With Treatment Emergent Adverse Events (TEAEs) — 40; 43 Participants
N/A N=12 Studies in Patients With Low Anterior Resection Syndrome (LARS)
Anterior Resection Syndrome · Bowel Dysfunction
Primary: Change of Anorectal Pressure Assessed With the Fecobionics Device — 9.8 cmH2O
N/A N=79 Comparative Study Between Two Fecal Management Systems
Anal Erosion
Primary: Number of Patients With Anal Erosion Within 14 Days After Insertion of FMS — 5; 5 Participants
N/A N=22 A Trial of Radiofrequency Ablation for Anal Intraepithelial Neoplasia Using the HALO Ablation System
HIV-negative Subjects With Intra-anal Intraepithelial Neoplasia Containing High-Grade Squamous Intraepithelial Lesions
Primary: Clearance of Anal HSIL (High Grade Squamous Intraepithelial Lesion (HSIL) — 19 participants w histological clearance
N/A N=115 Study to Evaluate Solesta for Treatment of Fecal Incontinence
Fecal Incontinence
Primary: Responder Rate in Number of Fecal Incontinence Episodes — 64.4 percentage of responders
Phase 2 N=45 Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus
Epidermoid Carcinoma · Anus
Primary: Percentage of Patients With Complete Response to Treatment — 30; 10; 0; 4 Participants
N/A N=50 Post-Marketing Clinical Follow-Up Trial to Evaluate the Performance and Safety of PROCTOeze® PLUS
Haemorrhoidal Disease
Primary: Assessment of Performance by the Improvement in the Quality of Life Measured Through the Score on The Short Health Scale for Haemorrhoidal Disease (SHSHD) — 14.04; 7.80…
N/A N=46 Anal Human Papillomavirus in Inflammatory Bowel Disease Study
Inflammatory Bowel Disease (IBD) · Ulcerative Colitis (UC) · Crohn's Disease (CD)
Primary: Number of Participants With Anal HPV of Any Type, Single Type, and Multiple Types — 41; 16; 25 participants
Phase 2 N=21 Effect of Sclerotherapy on Fistulas and Sinus Tracts in Hidradenitis Suppurativa
Hidradenitis Suppurativa
Primary: HS Physician Local Improvement Assessment - PAIN — 7; 7; 2 Participants