N/A N=82 Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
Septic Shock · Fluid Therapy · Hypotension
Primary: Cumulative Fluid Administered — 4417; 4110 mL of study fluid
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=47 FAST (Fluid Accumulation Status Trial)
Congestive Heart Failure · Cardiomyopathy · Dyspnea
Primary: Number of Subjects With at Least 30 Days of Daily Impedance Measurements — 47; 106 participants
Phase 4 N=170 Fluid Balance Study in Sick Neonates
Very Low Birth Weight Infant
Primary: Duration of Admission at the Ward in Days — 9; 8 number of days — p=<0.05
N/A N=20 A Net Ultrafiltration Challenge to Predict Preload-dependence (UF CHALLENGE)
Acute Kidney Injury
Primary: Diagnostic Performance of the Net Ultrafiltration (UF NET) Challenge to Detect de Novo Preload Dependence — 0.74 Proportion probability (0 to 1) — p=0.02
Phase 4 N=57 Loop Diuretics Administration and Acute Heart Failure
Acute Heart Failure
Primary: Evaluation of Mean Urine Output Volume During the Infusion Period — 2505; 2140 mL — p=0.04
N/A N=30 LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound
Dehydration in Children · Dehydration
Primary: Duration- Ultrasound Ordered to Completed — 154.4; 114.8 minutes
N/A N=30 A Randomized Controlled Trial of a Conservative Fluid Balance Strategy for Patients With Sepsis and Cardiopulmonary Dysfunction (BALANCE Study)
Sepsis
Primary: ICU-free Days to 14 Days After Enrollment — 9; 11 days
Phase 4 N=48 Hyperosmolar Saline Irrigation Fluid in Arthroscopic Knee Surgery
Arthroscopic Knee Surgery
Primary: Fluid Extravasation — 1.8; 1.2 centimeters
N/A N=68 Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
Intracranial Aneurysm · Brain Edema · Scoliosis
Primary: Number of ICU Stays Greater Than 1.5 Days — 13; 20 Number of ICU Stays greater that 1.5 Day
Phase 4 N=519 Acetazolamide in Decompensated Heart Failure With Volume OveRload (ADVOR)
Acute Decompensated Heart Failure · Volume Overload
Primary: Successful Decongestion — 79; 108 Participants
N/A N=64 Fluid Management in Transient Tachypnea of the Newborn
Transient Tachypnea of the Newborn
Primary: Duration of Respiratory Support — 45; 42 hours
Phase 3 N=45 Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial
Edema · Hypoproteinemia
Primary: Ventilator-free Days — 4; 13 days
Phase 2 N=81 Bolus of Saline in Stroke
Ischemic Stroke
Primary: The Percentage of Change in Optical Cerebral Blood Flow (oCBF) During Bolus Normal Saline Compared to Baseline, as Measured by Diffuse Correlation Spectroscopy (DCS)…
N/A N=150 Fluid Responsiveness Evaluation in Sepsis-associated Hypotension
Sepsis · Hypotension
Primary: Fluid Balance — 0.65; 2.02 Liters — p=0.021
N/A N=14 Effects of Exercise Training on Fluid Instability in Heart Failure Patients
Heart Failure
Primary: Bioelectrical Impedance Change — 47.52; 47.1; 41.27; 46.8 Percentage of Extra Cellular Fluid
Phase 4 N=40 Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach
Hypotension · Kidney Injury
Primary: Development of Renal Injury — 0.8; 0.74 mg/dL — p=0.31
N/A N=330 Assisted Fluid Management IDE Study
Non-Cardiac/ Non-Thoracic Surgery · Abdominal Surgery · Pelvic Surgery
Primary: Effectiveness of the Assisted Fluid Management Feature — 307 Participants
Phase 2 N=33 Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Acute Lung Injury
Primary: The Primary Efficacy Variable Will be the Total Reduction in Measured Lung Water
Phase 3 N=59 Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
Anesthesia
Primary: Change in Base Deficit — -1.5; -1.2; -0.5 mEq/L
N/A N=60 Does Fluid Requirement Decrease With the Use of Pneumatic Compression Device on Lower Limbs
Fluid Overload
Primary: Heart Rate at T0 — 85.23; 88.833 beats per minute — p=.443
Phase 2 N=30 Fluid Chloride and AKI in Cardiopulmonary Bypass
Acute Kidney Injury
Primary: Change in [TIMP2]*[IGFBP7] Biomarker — 0.015; 0.009 (ng/mL)^2/1000
N/A N=40 Closed-Loop Fluid Administration System Using Hemodynamic Monitors
Intraoperative Volume Status · Postoperative Complications
Primary: Fluid Status During Surgery — 95 percentage of case time
N/A N=111 Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Infection · Wound Healing Problem · Nonunion
Primary: The Number of Participants With Re-operations (All Subsequent Operative Procedures to Treat an Infection, a Wound Healing Problem, or a Nonunion). — 7; 6; 3; 10…
Phase 4 N=337 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
Acute Respiratory Failure · Intubation Complication
Primary: Number of Participants With Cardiovascular Collapse — 33; 31 Participants
N/A N=150 Traditional vs Oral Fluid Management in Total Knee Arthroplasty
Arthroplasty, Replacement, Knee
Primary: Body Weight — -1.9; -1.6 pounds
N/A N=13 FFA-Induced Hypertension and Endothelial Dysfunction
Endothelial Dysfunction · Hypertension
Primary: Change in Systolic Blood Pressure to After Completing an 8-hour Normal Saline Infusion in Obese Normotensive Subjects. — 13 mmHg
N/A N=5 Quantitative Characterization of Safe Irrigation for Ventricular Shunt Catheters
Hydrocephaly
Primary: To Demonstrate That the Flusher Can be Primed, Connected, and Activated in a Sterile Clinical Setting Per the Instructions for Use by the Treating Investigator . — 4; 4…
N/A N=3,000 REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery: RELIEF Study
Abdominal Surgery
Primary: Disability-free Survival — 165; 172 Participants
N/A N=80 Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers
Pressure Ulcer
Primary: Percentage of Participants With Successful Closure of Wound at 2 Weeks After Surgery — 85.7142857; 87.5 percent of participants
N/A N=80 Physiological Flow of Liquids in Healthy Swallowing
Deglutition · Healthy Swallowing · Aging
Primary: Number of Participants With Unsafe Swallowing — 7; 1; 3; 0 Participants