N/A N=48 Attention Disengagement Training for Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 68.1; 74.5; 60.0; 46.1 units on a scale
Clinical Trial Search
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N/A N=49 Interpretation Modification Program for Social Phobia
Social Anxiety Disorder · Social Phobia
Primary: Liebowitz Social Anxiety Scale (LSAS) — 82.0; 77.7; 50.2; 67.6 units on a scale
N/A N=106 Assessment and Treatment of Social Skills Deficits in Individuals With Social Phobia
Social Phobia
Primary: Social Phobia Remission
N/A N=89 Social Phobia Intervention Study of Mannheim
Social Phobia
Primary: Change From Baseline in Social Interaction Anxiety Scale (SIAS) — 43.13; 48.94; 34.85; 33.35 units on a scale — p=<0.05
N/A N=76 Internet Treatment for Social Phobia in Romania
Phobia, Social
Primary: Leibowitz Social Anxiety Scale - Self Report (LSAS-SR) — 78.60; 78.47; 73.69; 43.98 units on a scale — p=<0.01
Phase 4 N=181 Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety Disorder
Social Phobia
Primary: Rates of Remission (LSAS≤30) After 12 Weeks of Randomized Treatment During Phase II, Among Phase I Non-responders — 17; 11; 10 participants
Phase 3 N=27 Efficacy and Tolerability of Atomoxetine (Strattera) in Adult Patients With Generalized Social Anxiety Disorder
Generalized Social Phobia
Primary: Clinical Global Impression (Change Version, Also Known as Improvement Version) — 3; 4 participants
N/A N=250 1/2 A Multi-site Systems Intervention for Unemployed Persons With Social Anxiety
Social Anxiety
Primary: Liebowitz Social Anxiety Scale — 81.05; 82.74; 64.11; 73.05 score on a scale
Phase 2 N=69 Combined Treatment for Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder
Primary: Hamilton Anxiety Rating Scale (HAM-A) — 25.9; 23.8; 20.9; 19.4 units on a scale — p=.17
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=141 Telephone Psychotherapy for Late-Life Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder
Primary: Changes From Baseline in Penn State Worry Questionnaire (PSWQ-A) at Week 13 — -9.44; -5.37 units on a scale
Phase 2 N=83 SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
Phase 4 N=169 D-Cycloserine Enhancement of Exposure in Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 39.19; 42.44 units on a scale
N/A N=7 Testing Beliefs About Uncertainty in the Treatment of Generalized Anxiety Disorder
Generalized Anxiety Disorder
Primary: Clinician's Severity Rating (CSR) Scale of Anxiety Disorders Interview Schedule for DSM-IV (ADIS-IV) — 5.5; 3.14; 2.43 units on a scale
N/A N=76 A Comparison Between Cognitive, Behavioral, and Cognitive-Behavioral Therapy for Generalized Anxiety Disorder
Generalized Anxiety Disorder
Primary: High End State Function — 56.52; 43.48; 56.52; 47.62 % people meeting high endstate status
N/A N=41 Computer-Based Treatment for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change in Percent Dwell Time on Threat Faces — 20.7; 27.1 percentage of dwell time on threat faces
Phase 3 N=169 Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
Social Anxiety Disorder
Primary: Social Phobic Disorders Severity and Change Form — 2.68; 2.95 Units on a scale
Phase 3 N=409 Generalized Anxiety Disorder Adjunct Study
Anxiety · Anxiety Disorders · Anxiety Neuroses
Primary: Least Square Mean Change From Randomization to Week 8 in Hamilton Rating Scale for Anxiety (HAM-A) Total Score — -10.74; -9.61 units on scale
N/A N=90 Treatment of Social Anxiety Disorder and Selective Mutism
Social Anxiety Disorder · Selective Mutism
Primary: Change in Clinical Severity Ratings (CSR) of SAD & SM on the Anxiety Disorders Interview Schedule - Parent Version (ADIS-P) — -1.26; -1.65; -1.51; -1.24 units on a scale…
N/A N=88 Variations of Cognitive Behavior Therapy for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Social Phobia and Anxiety Inventory (SPAI) - Social Phobia Subscale — 131.66; 130.17; 75.47; 103.9 units on a scale
Phase 3 N=495 EDG004 Treatment of Adult Patients With Generalized Anxiety Disorder (GAD)
Generalized Anxiety Disorder (GAD)
Primary: Change From Baseline in Hamilton Anxiety Rating Scale (HAM-A) Total Score at Visit 7 (Day 42) — -9.01; -8.93 Score on scale
Phase 3 N=61 Adding Cognitive Behavioral Therapy to Drug Treatment for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 7.77; 7.84 units on a scale — p=.267
N/A N=53 Attention, Teleconferencing and Social Anxiety
Social Anxiety Disorder
Primary: Personal Report of Communication Apprehension Questionnaire — 88.06; 87.64; 95.69 score on a scale
N/A N=64 Cognitive-behavioral Therapy for Generalized Anxiety Disorder in Primary Care
Generalized Anxiety Disorder
Primary: Penn State Worry Questionnaire - Measure of Symptom Change — 42.1; 55.8 score on a scale — p=<0.05
Phase 4 N=49 Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)
Bipolar Disorder · Panic Disorder · Generalized Anxiety Disorder
Primary: Clinician Global Improvement Scale (CGI-21) — 7.8; 3.4 units on a scale
Phase 2 N=456 Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD Subjects
Generalized Anxiety Disorder
Primary: Change From Baseline to Week 8 in the Total Score on the Hamilton Anxiety Scale (HAM-A), as Assessed by the Site-trained Rater — -10.0; -9.3; -9.5 Units on a scale
Phase 3 N=402 Randomized Trial of Adult Participants With Generalized Anxiety Disorder
Generalized Anxiety Disorder
Primary: Change From Baseline in the HAM-A Total Score at Week 8 — -9.28; -9.35 score on a scale — p=0.917
N/A N=44 Efficacy of Virtual Reality Exposure Therapy Scripts for Social Phobia
Social Anxiety Disorder
Primary: Change From Baseline in the Social Phobia Diagnostic Questionnaire (SPDQ) at Post-treatment — -9.60; -4.46 score on a scale — p=< 0.05
Phase 3 N=224 PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
Social Anxiety Disorder
Primary: Subjective Units of Distress Scale (SUDS) Score — 77.7; 78.2; 62.3; 61.3 score on a scale — p=.5063
Phase 2 N=151 A Phase 2 Study of BNC210 for the Acute Treatment of Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change From Baseline to the Average Subjective Units of Distress Scale (SUDS) Score of the 5-minute Performance Phase of a Public Speaking Challenge — 22.42; 24.26…