30 closest matches · ranked by relevance
Genital Tract Mucosal Immunity · Genital Tract Microflora
Primary: %CD4 Expressing CCR5 HIV Co-receptor in the Cervix and Endometrium — 4.9; 11.7; 7.2 % of T-cells expressing CCR5 — p=0.80
Gonorrhoea
Primary: Rectal Mucosal IgG Concentrations (Geometric Mean Titers [GMT]) Against N. Gonorrhoeae Outer Membrane Vesicle (OMV) Antigen Ng1291 — 0.07; 0.072; 0.089; 0.097 titer
Women's Health · HIV Infection · Genital Diseases, Female
Primary: CD4+ to CD8+ T Cell Ratio in Cervical Biopsies — 0.46; 0.52 Cervical CD4+:CD8+ T cell ratio — p=0.6
Ulcerative Colitis
Primary: Change From Baseline of Mucus Production at 12 Weeks and 24 Weeks as Assessed by Histopathology
Human Immunodeficiency Virus · Virus Shedding
Primary: Semen Clearance (CL) of Tenofovir — 33.88; 51.21; 5.65 L/hr
HIV Infections
Primary: Raltegravir Male Genital Tract Concentration — 485.1 ng/mL
Influenza
Primary: Number of Participants From Each Arm Who Received Influenza Vaccine — 3; 8 Participants
HIV Infection · Vaginal Atrophy · Menopause
Primary: Change in Most Bothersome Symptom (MBS) of Vaginal Atrophy — 0; 1; 8; 4 Participants
HIV Infections
Primary: Number of Participants With Moderate or Greater Reactogenicity (i.e., Solicited Adverse Events) — 2; 4 Participants
HIV
Primary: Tissue Raltegravir Concentrations — 117 ng/mL
HIV-1-infection
Primary: Concentration of Doravirine in Seminal Plasma Fluid — 127 ng/ml
HIV · Sexually Transmitted Infections (STI)
Primary: Frequency of Use — 1.14; 1.31; 0.00; 0.00 units on a scale
Fertility · Contraception
Primary: Median Cervical Mucus Score - Baseline — 11; 13 score on a scale
Trachoma
Primary: Solicited Local Injection Site Reactions — 2; 8; 3; 9 Participants — p=1
Human Immunodeficiency Virus (HIV)
Primary: Epithelial Disruption Graded by a Pathologist Blinded to Study Intervention. — 1.0; 1.17 units on a scale — p=<0.05
Healthy Volunteers
Primary: Virus Infection — 8; 18 Participants
HPV Seroconversion
Primary: Number of Participants With Geometric Mean Antibody Concentrations by HPV Type — 15; 12; 8; 4 Participants
Influenza
Primary: Count of Participants From Each Arm Who Received Influenza Vaccine — 1; 3; 11; 13 Participants
Beta Haemolytic Streptococcal Infection
Primary: The Time to First Vaginal Swab That is Type III GBS Culture Positive, With All Previous Cultures Negative for Type III GBS, Not Just the Immediately Preceding Culture…
HIV
Primary: Safety: Grade 2 or Higher Adverse Events — 64; 61; 56 participants — p=0.88
Neisseria Gonorrhoeae Infection
Primary: Change in Anti-N. Gonorrhoeae Outer-membrane Vesicle Specific Immunoglobulin G (IgG) Concentrations After Immunization — 61.57; 206.2 titers
Prematurity
Primary: Concentration of APPs Before Oral Priming — 17; 22; 35; 42 femtomole (fmol)
HIV Infections · AIDS
Primary: the Percentage of CD3+/CD4+ Cells Per Cubic Millimeter at the Effector Sites in the Duodenal Tissues Obtained From Volunteers to the Antiretroviral Therapy Regimen Over…
Inflammatory Bowel Disease · Uterine Cervical Dysplasia
Primary: Twelve Month Antibody Response to the Human Papillomavirus (HPV) Vaccine (Geometric Mean Titers [GMT]) — 120.5; 175.0; 861.0; 68.9 mMU/mL
Sexually Transmitted Diseases · Gonorrhea · Chlamydia
Primary: Percentage of Study Successes in the EVO100 and Placebo Treatment Groups — 684; 696 Participants
Bacterial Vaginosis
Primary: Quantity of BV-associated Bacteria by qPCR and High-throughput Sequencing Tests — 5.59; 5.22; 4.91; 7.41 log10 copies/ml — p=0.011
Rectal Cancer
Primary: Change From Baseline in Tumor Immune Response Evaluated by Immunohistochemical (IHC) Analysis of Tumor Infiltrating Lymphocytes (TILs) at Week 14 (Post-surgery) — 0.609…
Cervical Epithelia
Primary: Number of Patients With Interferometric Data Acquired From Cervical Epithelium — 3; 41 patients
Respiratory Syncytial Virus Infections · Influenza, Human
Primary: Total Symptom Score — 29.25; 17.50; 11.00; 13.00 score on a scale
Human Papillomavirus
Primary: Geometric Mean Titers (GMTs) to HPV Types 16 and 18 — 6739.5; 6887.4; 1956.6; 1795.6 milli Merck Units/mL — p=<0.001