N/A N=983 Safety Assessment of Angioplasty Procedures
Angiospastic; Disorder
Primary: Number of Major Adverse Cardiac Events (MACE) — 9; 6; 2; 119 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=8 Healthy Heart Habits
Acute Coronary Syndrome · Depression
Primary: Acceptability Measured by the Client Satisfaction Questionnaire — 30.57 score on a scale
N/A N=58 Disease Management for Coronary Artery Patients
Patient Empowerment · Coronary Artery Disease
Primary: Compliance Questionnaire Scores of the Participants — 22.25; 22.53 score on a scale
Phase 2 N=20 Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI
Myocardial Ischemia
Primary: Quantification of Myocardial Blood Volume — 3.63; 1.23 seconds^-1
Phase 4 N=697 Evaluation of Integrated Cardiac Imaging in Ischemic Heart Disease
Ischemic Heart Disease
Primary: Diagnosis of IHD at Invasive Coronary Angiography and FFR Measurement — 140 participants
N/A N=48 Perceived Social Support, Heart Rate Variability, and Hopelessness in Patients With Ischemic Heart Disease
Ischemic Heart Disease
Primary: State Hopelessness — 1.25 units on a scale — p=<0.05
N/A N=1,154 The Healthy Heart Study
Cardiac Rehabilitation
Primary: Participation in Cardiac Rehabilitation — 231; 252 Participants — p=0.80
N/A N=5,179 International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA)
Cardiovascular Diseases · Coronary Disease · Coronary Artery Disease
Primary: Primary Composite Outcome: Death From Cardiovascular Causes, Myocardial Infarction, or Hospitalization for Unstable Angina, Heart Failure, or Resuscitated Cardiac Arrest…
Phase 3 N=40 Comprehensive Evaluation of Ischemic Heart Disease Using MRI
Heart Disease, Ischemic · Atherosclerosis, Coronary
Primary: Magnetic Resonance Image Quality Rating — 3.57; 2.55 units on a likert scale — p=<0.001
Phase 3 N=47 Effects of Ranolazine on Coronary Flow Reserve in Symptomatic Diabetic Patients and CAD
Diabetes, Type I · Diabetes, Type II · Angina
Primary: Change in Post-exercise Coronary Vasodilator Reserve — -4; 2 % change
N/A N=781 Using Digital Data to Predict CHD
Cardiovascular Diseases
Primary: Latent Dirichlet Allocation (LDA) Topics - Topics / Themes Discussed Between Patients With and Without Heart Disease — 0.85; 0.87; 0.55; 0.67 proportion probability AUC…
N/A N=177 Diabetes and Lipid Accumulationand Heart Transplant
Diabetes Mellitus · Heart Failure
Primary: Myocyte Lipid Accumulation as Oil Red-O Positive Biopsie — 54; 21; 0 Endomyocardial Biopsies
Early Phase 1 N=30 Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure
Heart Failure
Primary: Blood Flow — 300; 275 ml/min
N/A N=71 Dietary Prevention of Heart Failure in Hypertensive Metabolic Syndrome
Heart Failure
Primary: Carotid-femoral Pulse Wave Velocity — -0.3; 0.4 m/s — p=0.28
Phase 3 N=101 Exercise to Treat Depression in Individuals With Coronary Heart Disease
Depression · Heart Diseases
Primary: Hamilton Depression Rating Scale — -7.5; -6.1; -4.5 Raw changes in Ham-D scores
N/A N=45 Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
Spinal Cord Injuries · Heart Diseases
Primary: Percent Agreement Between Coronary Calcium Score (CCS) and National Cholesterol Education Program (NCEP) Guidelines — 18 percent agreement
N/A N=130 Improving Medication Adherence Through Graphically Enhanced Interventions in Acute Coronary Syndromes
Acute Coronary Syndrome (ACS)
Primary: Adherence to Refills and Medications Scale (ARMS) — 12.03; 12.18 units on a scale
Phase 2 N=28 Testosterone and Myocardial Perfusion in Coronary Heart Disease (CHD)
Coronary Heart Disease
Primary: Myocardial Perfusion — 1.83; 1.52 myocardial perfusion index
N/A N=123 Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
Hypertension · High Blood Pressure · Ventricular Hypertrophy
Primary: Clinically Significant Difference in Blood Pressure Lowering, Health Status and Quality of Life — -3.3; -4.9 mm Hg
N/A N=130 A Comparative Study of Different Treadmill Scores to Diagnose Coronary Artery Disease
Stable Ischemic Heart Disease
Primary: Exercise Treadmill Scores — 0.771; 0.772; 0.768 Probability by AUC
N/A N=51 PCI Alternative Using Sustained Exercise
Cardiovascular Disease
Primary: Myocardial Perfusion Reserve — 2.76; 2.47; 2.82; 2.52 Ratio
Phase 2 N=92 Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study)
Chronic Ischemic Heart Disease · Left Ventricular Dysfunction · Angina
Primary: Change in Maximal Oxygen Consumption (VO2max) — -0.6; 0.4 mL/kg/min — p=0.169
Phase 2 N=476 A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients
Coronary Heart Disease
Primary: Change From Baseline in % Flow Mediated Dilatation (FMD) — 0.09; 0.32 %FMD
Phase 2 N=15 Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Change in Flow Mediated Dilation — 0.26; -1.5 percentage of flow mediated dilation
N/A N=96 Vitamin D Repletion in Coronary Artery Disease
Vitamin D Deficiency · Coronary Artery Disease · Endothelial Dysfunction
Primary: Endothelial Function — 0.13; -0.04 reactive hypermia index
Phase 4 N=39 The Effect of Nebivolol in Hypertensive Patients With Coronary Artery Disease
Hypertension · Coronary Artery Disease
Primary: Peripheral Diastolic Blood Pressure (DBP) — 81.1; 78.2; 78.0; 79.3 mmHg
N/A N=18 Role of Infected Blood Dendritic Cells in Heart Disease Risk
Chronic Periodontitis
Primary: Frequency of Blood Dendritic Cells From Baseline — 12; 14 % MFI
N/A N=335 Heart Failure Study: The Atlanta Cardiomyopathy Consortium
Heart Failure
Primary: Death, Heart Transplant, Left Ventricular Assist Device Implantation — 35 participants
N/A N=306 Data Acquisition for Optimization of Coronary Artery Disease (CAD) Algorithm
Coronary Artery Disease
Primary: The Area Under the Receiver Operating Characteristic Curve of the CAD-score to Separate CAD From Non-CAD Patients. — 73.4 percentage of 100
N/A N=14 Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart Failure
Diastolic Heart Failure · Hypertensive Heart Disease
Primary: Brachial Artery Flow-mediated Dilation (FMD) — 5; 8 % dilation — p=.17