Phase 2 N=63 Phase 2 Herniorrhaphy Study for Opioid Elimination
Postoperative Pain
Primary: Percentage of Subjects Receiving no Opioid Rescue — 30; 27 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=100 Inguinal Hernia Study Using Biodesign IHM
Inguinal Hernia
Primary: Number of Patients With Inguinal Hernia Recurrence — 3; 0 participants — p=0.11
N/A N=124 Modified "Open Intraperitoneal Mesh" Technique of Incisional Ventral Hernia Repair
Incisional Ventral Hernia · Recurrent Ventral Hernia
Primary: Number of Early Postoperative Complications (Wound Infections, Seroma, Hematoma) — 9; 21; 2; 92 participants
N/A N=299 Lichtenstein Patch or Prolene Hernia System (PHS) for Inguinal Hernia Repair
Chronic Pain
Primary: Long-term Sequelae — 10; 13 percentage of participants
N/A N=34 Mesh Fixation and Closure of Peritoneum Following Laparoscopic Hernia Repair Using N-butyl Cyanoacrylate
Hernia, Inguinal
Primary: Number of Participants With Safe Fixation of Mesh and Closure of Peritoneum by Clinical Investigation During Hospital Stay and Telephone Interview at Six Weeks…
N/A N=58 Comparative Study on Self-adhesive Mesh for Open Inguinal Hernia Repair
Hernia, Inguinal
Primary: Operating Time From Skin Incision to Wound Closure — 39.2; 47.7 minutes
N/A N=9 SurgiMend Mesh at the Hiatus
Hiatal Hernia
Primary: Recurrence Rate — 6; 3 Participants
Phase 2 N=463 Pilot Herniorrhaphy Study for Postoperative Analgesia
Postoperative Pain
Primary: Mean Summed Pain Intensity (SPI) Score — 83.71; 77.63; 95.24; 89.28 Units on a scale
N/A N=41 Miromatrix Biological Mesh for Hiatal Hernia Repair
Hiatal Hernia
Primary: Number of Subjects With a Hernia Recurrence Requiring Reoperation — 0 Participants
N/A N=101 Open Versus Robotic Retromuscular Ventral Hernia Repair
Ventral Hernia
Primary: Composite Outcome of Diagnosis of Surgical Site Occurrence or Infection, Hospital Readmission, or Hernia Recurrence — 9; 9 Participants
Phase 4 N=172 Strattice in Repair of Inguinal Hernias
Hernia, Inguinal
Primary: Change From Baseline in Activities Assessment Scale at 3 Months — -7.49; -6.12 units on a scale
N/A N=119 Study Of Hernia Repair Utilizing The Bard Ventrio Hernia Patch
Ventral Hernia
Primary: The Primary Endpoint is the Rate of Hernia Recurrence in Study Patients. — 0 participants
N/A N=402 Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery
Hernia · Obesity
Primary: Incisional Hernia — 32; 38 participants — p=0.60
N/A N=126 A Prospective Study in Patients Undergoing Primary Ventral Hernia Repair Using Parietex™ Composite Ventral Patch
Hernia
Primary: Primary Hernia Recurrence Rate at 24 Month Follow-up. — 3 Participants
N/A N=104 Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement
Ventral Incisional Hernia
Primary: Hernia Recurrence Rate — 17.3 % of subjects with recurrent hernia
N/A N=92 Ventral Hernia Study Using OviTex Reinforced Bioscaffold
Hernia, Ventral
Primary: Surgical Site Occurrences or Wound-related Events — 0; 10; 3; 4 Participants
N/A N=491 Urinary Retention After Laparoscopic Inguinal Hernia Repair: Comparing the Use of the Intraoperative Urinary Catheter
Inguinal Hernia
Primary: Number of Participants With Post Operative Urinary Retention — 23; 21 Participants
N/A N=200 TAPP Inguinal Hernia Repair With Self-fixating Parietex™ ProGrip™ Mesh
Postoperative Complications
Primary: Proportion of Subjects Who Experience Hernia Recurrence (Defect Treated Initially With Parietex™ ProGrip™) Within 12 Months Post-surgery. — 3 participants
Phase 3 N=418 Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
Postoperative Pain
Primary: Mean Area Under the Curve (AUC) of the Numeric Rating Scale (NRS) Pain Intensity Scores With Activity (NRS-A) Through 72 Hours Postsurgery (AUC0-72), Compared With…
N/A N=75 Laparoscopic vs. Robotic Ventral Hernia Repair With IPOM
Ventral Hernia
Primary: Postoperative Pain Scores — 5; 5; 4; 3 score on a scale
N/A N=38 Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair
Hernia, Inguinal
Primary: Mean Operative Time — 69; 84; 40; 66 minutes — p=0.17
N/A N=112 Stoma Closure and Reinforcement Trial
Colon Cancer · Rectal Cancer · Ileostomy - Stoma
Primary: Number of Participants With Wound Occurrences — 0 Participants
N/A N=334 Effect of Suture for Mesh Fixation in Lichtenstein Hernia Repair
Inguinal Hernia
Primary: Pain, Numbness and Discomfort in the Groin — 28; 34 participants
Phase 3 N=425 Surgical Pain After Inguinal Hernia Repair (SPAIHR)
Pain, Postoperative · Hernia, Inguinal
Primary: Modified Brief Pain Inventory-Short Form (mBPI-sf): Worst Pain 24 Hours Post Surgery — 5.2; 5.4; 4.7; 5.4 scores on scale — p=0.0668
Phase 4 N=20 Awake Caudal Catheter vs General Anesthesia
Inguinal Hernia
Primary: Number of Participants With Return to Baseline Respiratory Function. — 11; 9 Participants
Phase 2 N=50 Safety and Efficacy of CollaRx® Bupivacaine Implant in Men After Open Laparotomy Herniorrhaphy
Herniorrhaphy · Postoperative Pain · Inguinal Hernia
Primary: Sum of Pain Intensity Defined as Area Under the Curve (AUC) of 100-mm VAS PI Scores. — 2810.4; 3484.5 score on a scale*hour
N/A N=90 A Retrospective Study With Prospective Follow-Up of Laparoscopic Ventral Hernia Repair Utilizing the Bard Sepramesh IP Composite
Hernia
Primary: Hernia Recurrence Rate of Hernias Post Repair With Sepramesh. — 1 participants
Phase 2 N=10 Assess the Feasibility and Efficacy of the CollaRx® Bupivacaine Implant Laparoscopic Inguinal or Umbilical Herniorrhaphy
Hernia · Postoperative Pain
Primary: Total Use of Opioid Analgesia - Morphine Equivalence (mg) — 19.3 Morphine Equivalence (mg)
N/A N=75 Xen Matrix™ AB Surgical Graft in Ventral or Incisional Midline Hernias
Incisional Hernia
Primary: Number of Participants With Wound Occurrences Up to 45 Days Post Implantation — 11 Participants
N/A N=77 Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal Hernia · Postoperative Pain
Primary: Numerical Rating Scale Pain Score — 3.3; 3.9 units on a scale