N/A N=16 HypErthermia as an Additional Treatment for the Biology and Experience of Depression
Major Depressive Disorder
Primary: Average Number of Planned WBH Sessions Completed — 7.83; 3.20 Count of WBH Sessions
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=21 Body Temperature in Persons With Tetraplegia When Exposed to Heat
Spinal Cord Injury
Primary: Core Body Temperature — 2.04; -0.05 Percent Change — p=0.0001
Phase 4 N=20 Temperature Control in Central Fever in the Neuro-ICU
Fever · Brain Hemorrhage
Primary: Core Temperature as Measured With an Approved Device (Urinary Catheter) in Place for Usual Clinical Care — 100.8; 100.3; 99.9; 99.5 degrees F
N/A N=30 HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2
Major Depressive Disorder · Depression
Primary: Net Promoter Score, and Enrollment Likelihood — 7.73; 8.00; 4.13; 4.29 score on a scale
Phase 4 N=30 Body Temperature in Persons With Tetraplegia When Exposed to Cold
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Visit 1: Percent Change in Core Body Temperature — -1.2; 0.05 Percent Change — p=<0.01
N/A N=42 Intraoperative Warming Comparison of Devices
Hypothermia
Primary: Percent of Patients With an Average Intraoperative Temperature Greater Than or Equal to 36 Celcius — 56; 90 percentage of participants — p=0.027
N/A N=15 A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
Spinal Cord Injuries
Primary: Skin Temperature (Tsk) Change — -5.6; -6.9; 2.1 Degrees Celsius — p=0.002
N/A N=80 Hyperthermic Yoga for Depressive Symptoms
Depression · Major Depressive Disorder
Primary: Depressive Symptoms as Measured by the Inventory of Depressive Symptomatology - Clinician Rated (IDS-CR) — 17.93; 29.63 units on a scale
N/A N=41 Effect of Heat Exposure on Cognition in Persons With Tetraplegia
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Change in Core Body Temperature From Baseline to 120 Minutes Post Warm Challenge — 0.59; -0.05 degrees Centigrade
N/A N=30 Transnasal Induction of Normothermia in Febrile Stroke Patients
Stroke, Ischemic · Stroke Hemorrhagic · Fever
Primary: Cooling Performance — 19 Participants
N/A N=5,056 Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
Perioperative Care · Surgery--Complications · Hypothermia; Anesthesia
Primary: Number of Participants With a Composite Outcome Consisted of Myocardial Injury After Non-cardiac Surgery (MINS), Non-fatal Cardiac Arrest, and All-cause Mortality — 239…
N/A N=14 Heated Humidified Breathing Circuit Rewarming in Hypothermic Post Cardiopulmonary Bypass Patients.
Hypothermia · Rewarming
Primary: Time to Normothermia — 4.4 hours
N/A N=22 Local Heat Stress in Autonomic Failure Patients With Supine Hypertension
Hypertension · Pure Autonomic Failure · Multiple System Atrophy
Primary: Change in Systolic Blood Pressure — 19; 3 mm Hg
Phase 4 N=30 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
Tetraplegia · Hypothermia · Mild Cognitive Impairment
Primary: Change in Core Body Temperature — -0.24; -0.97; NA; 0.79 °C — p=<0.001
N/A N=101 California Transport Cooling Trial
Hypoxic Ischemic Encephalopathy
Primary: Percentage of Temperatures in Target Range During Transport — 0; 73 Percentage of temperatures — p=<0.001
N/A N=17 Chronic Passive Heating in Individuals With T2DM
Type2 Diabetes
Primary: Insulin Sensitivity — 0.31; 0.33; 0.10; 0.10 AU
Phase 3 N=295 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-OH [Out of Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 27; 15; 111; 107 Participants — p=0.14
N/A N=329 Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Cardiac Arrest
Primary: Survival With Good Neurobehavioral Outcome — 48; 48; 85; 76 Participants — p=0.63
N/A N=111 Comparison Study of Core Temperature Thermometry Systems
Thermometry Device Comparisons
Primary: Temperature Agreement in Degrees Celsius. — NA; 0.5; 0.5; 0.4 Temperature in Celsius
N/A N=41 Heat Therapy Versus Exercise Training in Hypertension
Hypertension · Cardiovascular Diseases · Arterial Hypertension
Primary: Blood Pressure Reduction: Change in Systolic and Diastolic Ambulatory Blood Pressure (mmHg) After 30 Sessions of Intervention — -1; 0; 0; 1 mmHg
N/A N=389 Mild Versus Moderate Therapeutic Hypothermia in Out-of-hospital Cardiac Arrest Patients
Cardiac Arrest
Primary: Number of Participants With Death or Poor Neurologic Outcome at 6 Months — 89; 83 Participants
Phase 3 N=1,359 Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest
Out-of-hospital Cardiac Arrest
Primary: Number Alive at Hospital Discharge — 187; 183; 62; 76 participants
N/A N=120 Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia
Children Requiring MRI
Primary: Change in Body Temperature in Children Undergoing MRI Under General Anesthesia (GA)and Change in Room Temperature Before and After MRI — 36.7; 36.3; -0.4; 21.1 celsius…
N/A N=325 TOBY (TOtal Body hYpothermia): a Study of Treatment for Perinatal Asphyxia
Asphyxia Neonatorum · Hypoxia · Encephalopathy
Primary: Combined Incidence of Mortality and Severe Neurodevelopmental Disability in Survivors — 74; 86 participants
N/A N=168 Late Hypothermia for Hypoxic-Ischemic Encephalopathy
Infant, Newborn · Hypoxia, Brain · Hypoxia-Ischemia, Brain
Primary: Death or Moderate or Severe Disability — 19; 22 Participants
Phase 2 N=30 Caffeinol Hypothermia Protocol
Acute Ischemic Stroke
Primary: Number of Participants With Symptomatic Intracerebral Hemorrhage — 0 participants
N/A N=120 Observational Examination of Thermoregulation in Total Joint Arthroplasty
Hypothermia
Primary: Incidence of Hypothermia — 74 Participants
N/A N=20 Radiofrequency Hyperthermia Safety Study
Chronic Pain · Soft Tissue Injuries · Wound Heal
Primary: Mean Temperature Change- Skin Evaluation on Leg With Device — 6.21 degrees
N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
N/A N=73 Comparison of Vital HEAT (vH2) Temperature Management System to Upper-body Forced-air Warming
Surgery
Primary: Intraoperative Distal Esophageal (Core) Temperature — 35.96; 35.87 °C — p=<0.0001