N/A N=1,600 Social Media And Risk-reduction Training for Infant Care Practices (SMART)
Risk Reduction
Primary: Adherence With Recommended Supine Sleep Position — 230; 294; 294; 243 Participants — p=0.03
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=44,567 Antenatal Micronutrient Supplementation and Infant Survival
Infant Mortality · Preterm Birth · Low Birth Weight
Primary: Infant Mortality Through 6 mo of Age — 764; 741 participants — p=0.36
Phase 3 N=59,721 Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
Vitamin A Deficiency · Maternal Mortality · Infant Mortality
Primary: All-cause, Pregnancy-related Mortality — 41; 47; 50 Participants — p=0.05
N/A N=3,188 Low-birthweight Infant Feeding Exploration
Low Birthweight · Pre-Term
Primary: Length-for-Age Z-score — -1.43 Z-score
Phase 4 N=21,832 Neonates and Azithromycin, an Innovation in the Treatment of Children in Burkina Faso
Childhood Mortality
Primary: 6 Month Mortality - All Cause — 42; 50 Participants
N/A N=14,490 Smart Discharges for Mom & Baby
Maternal Sepsis · Neonatal Sepsis
Primary: Post-discharge Readmission or Mortality — 231; 349 Participants
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
N/A N=5,020 Mobile WACh NEO: Mobile Solutions for Neonatal Health and Maternal Support
Neonatal Death · Perinatal Death · Depression
Primary: Neonatal Mortality — 46; 37 Participants — p=0.314
N/A N=150 Trial Comparing Iron Supplementation Versus Routine Iron Intake in Very Low Birth Weight Infants
Iron Deficiency Anemia
Primary: Hematocrit (Hct) at 36 Wks Post Menstrual Age (PMA) — 29.2; 28.2 % Hematocrit — p=0.59
N/A N=111 Cerebral Oxygenation and Autoregulation in Preterm Infants
Intraventricular Hemorrhage of Prematurity · Complications of Prematurity
Primary: Mortality Before Hospital Discharge — 11 Participants
Phase 2 N=104 Red Blood Cell (RBC) Survival Following Transfusion in Infants
Neonatal Anemia
Primary: Number of Discrete Biotinylated RBC Densities (up to 5 Discrete Densities) That Can be Accurately Measured by Flow Cytometry, i.e., Without Overlap. — 5; 5 flow…
N/A N=170 Verbal Autopsy of Maternal Deaths, Stillbirths, and Neonatal Deaths in BetterBirth
Perinatal Death · Neonatal Death · Stillbirth
Primary: Cause of Death — 20; 35; 56; 50 Participants
Phase 3 N=362 Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight
Candidiasis
Primary: Death or Candidiasis — 31; 37 participants
N/A N=30 Healthy Eating for My Infant (HEMI)
Pediatric Obesity
Primary: Group Differences in Infant BMI — 5; 2; 9; 11 Participants
N/A N=2,221 Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
Kangaroo Mother Care · Preterm Infant · Death; Neonatal
Primary: Mortality Within 7 Days — 81; 83 Participants
N/A N=605 Umbilical Cord Milking in Non-Vigorous Infants Developmental Followup (MINVIFU)
Neurodevelopmental Abnormality
Primary: Total and Domain Scores on the Ages and Stages Questionnaire, Third Edition. — 55; 55; 60; 60 score on a scale — p=0.87
N/A N=10 Measurement of Body Fat in Infants
Brown Adipose Tissue · Body Composition
Primary: Whole Body Fat Mass — 20.8 percentage of fat mass
N/A N=82 Effectiveness of Synagis (Palivizumab) Immunoprophylaxis in Preterm Infants With High Risk of Severe Respiratory Syncytial Virus (RSV) Infection
Respiratory Syncytial Virus Infection
Primary: Number of Hospital Admissions by Respiratory Syncytial Virus Infection — 2 participants
N/A N=2,288 Alive & Thrive Evaluation in Burkina Faso
Breast Feeding · Breast Feeding, Exclusive
Primary: Exclusive Breastfeeding on the Day Preceding the Interview as Assessed by Cross Sectional Survey — 0.933; 0.512 percentage of exclusive breastfeeding
Phase 4 N=77,664 Community Health Azithromycin Trial in Burkina Faso
Childhood Mortality
Primary: All-cause Mortality Rate in Children Aged 1-59 Months — 8.2; 10.0 deaths per 1000 person years
N/A N=20 A Novel Parent Education Program for Early Intervention
Preterm Infant · Full-term Infant
Primary: Alberta Infant Motor Scale - Change in Total Percentile Score — 10; 0 change in percentile rank — p=0.016
Phase 2 N=134 Prophylactic Probiotics to Extremely Low Birth Weight Prematures
Feeding; Difficult, Newborn · Growth Failure · Necrotizing Enterocolitis
Primary: Time to Establish Full Enteral Feeds — 15; 15 days
N/A N=441 Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study)
Respiratory Depression Neonatal
Primary: Mean Duration of Suctioning Among All Live Births — 21.9; 15.7; 34.1; 23.2 seconds
N/A N=1,052 Effect of Presenting Survival Information as Text or Pictograph During Periviable Birth Counseling
Premature Birth
Primary: Hypothetical Treatment Choice — 130; 135; 143; 126 Participants
N/A N=103,117 Trial of the Use of Antenatal Corticosteroids in Developing Countries
Preterm Birth
Primary: Neonatal Mortality Rate at 28 Days in <5th Percentile Birth Weight Infants (as a Proxy Measure for Prematurity) — 566; 524 Participants — p=0.65
N/A N=130 Electricity-free Infant Warmer for Newborn Thermoregulation in Rwanda
Hypothermia Neonatal
Primary: Temperature/Effectiveness — 179; 4; 21 Number of infant warmer uses
N/A N=3,003 Impact of Heart Rate Characteristics Monitoring in Neonates
Sepsis
Primary: Number of Ventilator-free Days — 95.9; 93.6 days — p=0.08
N/A N=38 Feeding and Wellness Among Late Preterm Infants
Late Preterm Infant
Primary: Phone Call Completion Rate — 194; 102; 59; 52 calls
N/A N=666 ASPIRIN: Neurodevelopmental Follow-up Trial
Neurodevelopmental Abnormality
Primary: Bayley Scales of Infant and Toddler Development, 3rd Edition (Bayley-III) Cognitive Composite Score — 96; 96.8 score on a scale — p=0.25
N/A N=377 Age of Red Blood Cells in Premature Infants Study (ARIPI)
Premature Birth
Primary: 1. Composite Outcome of Necrotizing Enterocolitis, Intraventricular Hemorrhage, Bronchopulmonary Dysplasia and Retinopathy of Prematurity at 30 and 90-days. 2. Mortality…