N/A N=124 Newborn Feeding and Infant Phenotype
Breast Feeding
Primary: Change in Total Adipose Tissue Volume — 0.718; 0.901; 0.775 Litres
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=3,188 Low-birthweight Infant Feeding Exploration
Low Birthweight · Pre-Term
Primary: Length-for-Age Z-score — -1.43 Z-score
N/A N=10 Measurement of Body Fat in Infants
Brown Adipose Tissue · Body Composition
Primary: Whole Body Fat Mass — 20.8 percentage of fat mass
N/A N=34 Healthy Start to Feeding Intervention
Weight, Body · Diet Habit
Primary: Weight-for-Length Percentile — 44.94; 46.70; 58.69; 48.54 Percentile
N/A N=94 Infant Environment Study
Infant Development · Motivation
Primary: Change in Infant Food Reinforcing Proportion — 0.66; 0.64; 0.53; 0.54 proportion food response/total response — p=0.016
N/A N=30 Healthy Eating for My Infant (HEMI)
Pediatric Obesity
Primary: Group Differences in Infant BMI — 5; 2; 9; 11 Participants
N/A N=10 Phthalate and Bisphenol Exposure During Minipuberty
Phthalate Exposure · Bisphenol Exposure
Primary: Log Signal Intensity of Bisphenol A (BPA) in Child Urine Samples — 0.00; 5.43 Log(Arbitrary Units)
N/A N=97 Sensitive Periods in Human Flavor Learning
Development
Primary: Vegetable Flavor Acceptance [Infants' Intake] — 56.8; 42.4; 29.0; 40.7 intake in grams — p=0.02
Phase 3 N=483 Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants
Infant, Newborn · Infant, Small for Gestational Age · Infant, Extremely Low Birth Weight
Primary: Bayley Scales of Infant Development (BSID) Cognitive Composite Score — 80.7; 81.1 Score on a scale
N/A N=248 Trial to Improve Multisensory Neural Processing, Language & Motor Outcomes in Preterm Infants
Preterm Infant
Primary: Index of Multisensory Processing (IMP) — 31.4; 49.0; 35.6; 18.8 percentage of time
Phase 1 N=20 An Open Label Study to Describe the Pharmacokinetics of Daptomycin in Infants
Sepsis
Primary: PK of Daptomycin — 262.4 mg*h/L
N/A N=128 Babies' Expectations About Racial Interactions
Infant Behavior
Primary: Participants' Average Time Spent Looking at Stimuli According to Condition — 10.72; 10.07; 10.99; 9.53 seconds — p=<.05
N/A N=168 Neurodevelopmental and Growth Outcomes of Early, Aggressive Protein Intake in Very Low Birthweight Infants
Prematurity
Primary: Number of Participants With Weight<10th Percentile for Age — 32; 41 Participants
N/A N=71 Learning to Love Mealtime Together
Infant Obesity · Parenting · Feeding Behavior
Primary: Infant Weight-for-Length Z Scores — 0.43; 0.12 z-score — p=0.07
N/A N=45 A Study Evaluating Sleep, Stress and Infant Nutrition Using a Chatbot
Preterm Birth · Healthy
Primary: Number of Chats on Sleep, Stress and Infant Nutrition — 131; 125 Chats
N/A N=20 Temperature Monitoring With InnerSense Esophageal Temperature Sensor/Feeding Tube After Birth Through Stabilization in VLBW Infants
Body Temperature
Primary: Mean Axillary Admission Temperature — 36.77; 36.68 Degrees Celsius — p=0.7294
Phase 4 N=20 INF108F in Infants With Food Protein Induced Proctocolitis
Infant Development · Gut Microbiome · Food Protein Induced Allergic Proctocolitis
Primary: Changes to Gut Microbiome Composition — 42.816; -12.413 Change in %B.infantis reads (Day 28-BL) — p=0.154
N/A N=53 Form, Fit, and Function of INVSENSOR00061
Healthy
Primary: INVSENSOR00061 SpO2 Accuracy — 1.02 % of SpO2
N/A N=20 A Novel Parent Education Program for Early Intervention
Preterm Infant · Full-term Infant
Primary: Alberta Infant Motor Scale - Change in Total Percentile Score — 10; 0 change in percentile rank — p=0.016
Phase 3 N=144 Effect of Early L-Carnitine Supplementation on Neurodevelopmental Outcomes in Very Preterm Infants
Prematurity · Neurodevelopmental Disorder · Carnitine Deficiency
Primary: Time to Regain Birthweight in Infants Who Receive L-carnitine Supplementation Compared to Controls — 8.12; 8.4 days — p=<0.05
N/A N=19 Sleep Device Testing to Promote Sleep in Infants
Insomnia Chronic
Primary: Change in Number of Nighttime Awakenings Per Night as Measured by Parent Sleep Diary — -0.88 awakenings per night — p=0.000393
N/A N=150 Trial Comparing Iron Supplementation Versus Routine Iron Intake in Very Low Birth Weight Infants
Iron Deficiency Anemia
Primary: Hematocrit (Hct) at 36 Wks Post Menstrual Age (PMA) — 29.2; 28.2 % Hematocrit — p=0.59
Phase 2 N=183 Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002)
Respiratory Tract Infection · Respiratory Syncytial Virus
Primary: Percentage of Participants Who Experienced At Least One Solicited Injection Site Adverse Event (AE) — 3; 3; 3; 2 Participants
N/A N=171 Unintentional Overfeeding of Formula Fed Infants
Childhood Obesity · Infant Development
Primary: Focus Group Recommendations to Improve Infant Formula Preparation Instructions — 60; 80; 100; 60 percentage of focus group participants
N/A N=27 Effects of Vanilla on Hypoxic Intermittent Events in Premature Infants
Premature Birth · Neonatal Hypoxic Conditions
Primary: Desaturation Index — 51.7; 56.9 Number of events
N/A N=36 SmarToyGym: Smart Detection of Atypical Toy-oriented Actions in At-risk Infants
Cerebral Palsy · Developmental Delay · Stroke
Primary: Center of Pressure, Path Length Per Second - No Toy (Birth Status) — 0.0282; 0.0428 centimeters per second (cm/sec) — p=0.0054
N/A N=21 Inflammatory Cytokine Quantification in Infants
Sepsis · Congenital Diaphragmatic Hernia · Neonatal Cardiopulmonary Failure
Primary: TNF-alpha, Baseline — 8.88 pg/mL
N/A N=111 Cerebral Oxygenation and Autoregulation in Preterm Infants
Intraventricular Hemorrhage of Prematurity · Complications of Prematurity
Primary: Mortality Before Hospital Discharge — 11 Participants
N/A N=70 Supporting and Enhancing NICU Sensory Experiences (SENSE)
Premature Birth of Newborn
Primary: Ages and Stages Questionnaire (ASQ) - Communication at 1 Year — 38.6; 48.6 score on a scale
N/A N=198 Feeding and Transition to Home for Preterms at Social Risk
Premature Birth
Primary: Infant Behavioral Organization — 33.2; 51.8 Orally directed behavioral cues per week