N/A N=229 Toric Intraocular Lens Following Cataract Surgery
Cataract · Astigmatism
Primary: Percent Reduction in Absolute Cylinder — 84.975; 46.498 percentage of intended cylinder reduct
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=78 Evaluation of 3 Intraocular Lenses Following Lens Extraction
Cataract
Primary: Mesopic Monocular Contrast Sensitivity Without Glare 1.5 and 3 Cycles/Degree — 1.494; 1.576; 1.410; 1.613 log contrast sensitivity units
Phase 4 N=93 Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
Cataract
Primary: Monocular Mesopic Contrast Sensitivity Without Glare (1.5, 3 Cycles/Degree) — 1.612; 1.582; 1.527; 1.658 log contrast sensitivity units
Phase 4 N=132 Presbyopia-Correcting Intraocular Lenses (IOLs)
Cataract
Primary: Best Corrected Visual Acuity — -0.075; -0.080; -0.081; 0.227 logMAR
N/A N=218 Clinical Investigation of the Next Generation Intraocular Lens
Cataract
Primary: Monocular, Photopic Distance Corrected Intermediate Visual Acuity (DCIVA) at 66 Centimeter (cm) — 0.053; 0.370 logMAR — p=< 0.0001
N/A N=32 Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
Aphakia · Corneal Astigmatism
Primary: Percentage of Eyes With ≤ 0.25 Diopter (D) Absolute Refractive Cylinder at Visit 3/3A (Day 30-60) — 90.2 percentage of eyes — p=<0.0001
Phase 3 N=405 Safety and Efficacy of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
Intraocular Lens Replacement
Primary: Mean Area-under-the-Curve (AUC) Analysis of Change From Baseline in Pupil Diameter (mm) During Surgery — 0.1; -0.5 mm — p=<0.0001
N/A N=35 Clinical Performance of a Phakic Intraocular Lens (IOL)
Presbyopia
Primary: Number of Eyes With Monocular Uncorrected Near Visual Acuity of 20/40 or Better at 40 cm 6 Months After Implantation — 66 Eyes
Phase 4 N=26 Low Cylinder Toric
Cataracts
Primary: Uncorrected Distance Visual Acuity — 0.09 logMAR
N/A N=193 Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
Aphakia
Primary: Percentage of Subjects Not Bothered at All by Halos (QUVID Question 2.3) — 88.7; 58.1; 58.6 percentage of subjects
Phase 3 N=416 Safety, Efficacy and Pharmacokinetics of OMS302 in Subjects Undergoing Intraocular Lens Replacement With Phacoemulsification
Intraocular Lens Replacement
Primary: Mean Area Under the Curve Analysis of Change-from-Baseline in Pupil Diameter (mm) During Surgery — 0.1; -0.5 mm — p=0.0001
Phase 3 N=122 One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
Aphakia · Cataract
Primary: Visual Acuity — 108 Participants
Phase 4 N=100 Clinical Investigation of the Bi Flex M Multifocal IOL
Cataract
Primary: Long Term Monocular Visual Acuity (VA) — 0.192; 0.205; 0.614; 0.319 LogMAR
N/A N=320 Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
Cataracts
Primary: Mean Photopic Monocular Distance Corrected VA (53 cm) at Day 120-180 — 0.322; 0.512 logMAR
Phase 3 N=269 Clinical Evaluation of a 1-Piece Intraocular Lens
Cataract
Primary: Mean Percent Reduction in Cylinder — 32; 75; 76. percentage of reduction in cylinder — p=<0.0001
N/A N=448 Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
Refractive Errors · Myopia · Myopic Astigmatism
Primary: Unaided Visual Acuity After the Procedure — 0.264; 0.227 LogMar vision
N/A N=68 Clinical Investigation of the AcrySof® IQ PanOptix™ IOL
Cataract
Primary: Monocular Photopic Best Corrected Distance Visual Acuity (5 m) — 15; 5; 9; 8 subjects
Phase 4 N=76 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
Cataract
Primary: Visual Acuity — 0.54; 0.06; 0.03; 0.04 logMAR
N/A N=15 ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)
Bilateral Cataract
Primary: Number of Subjects Reporting Spatial Distortions Related to Intraocular Lens (IOL) Misalignment — 11; 2 Participants
N/A N=98 Corrected VA With Long-Term Follow-Up After AcrySof® Intraocular Lens (IOL) Implantation
Pseudophakia
Primary: Mean Change From Baseline in Best Corrected Visual Acuity (BCVA) at the Long-Term, Post-Implantation Visit — -0.06; -0.09; -0.07; 0.01 logMAR
N/A N=65 AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL) Clinical Study in Japan
Cataracts
Primary: Monocular Uncorrected Distance Decimal Visual Acuity — 3; 3; 1; 0 participants
N/A N=64 AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
Cataracts
Primary: Uncorrected Decimal VA (5 m) — 48; 3; 1; 0 participants
N/A N=74 Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
Cataracts
Primary: Percentage of Eyes Achieving a Manifest Refraction Spherical Equivalent (MRSE) Within ± 0.50 D of the Intended Adjustment Target — 78.3; 80.0; 79.2 percentage of eyes
Phase 4 N=64 A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
Cataract
Primary: Defocus Curve — 0.585; 0.653; 0.490; 0.475 LogMAR
N/A N=24 A Comparison of Aspheric Toric Intraocular Lens (IOL) Implantation Versus Aspheric Non-Toric Lens Implantation
Cataract
Primary: Monocular Uncorrected Distance Visual Acuity (Monocular UCDVA) at Month 3 — 0.089; 0.225 logMAR
N/A N=64 ReSTOR Natural +3.0D Study In Japan
Cataract
Primary: Uncorrected Intermediate Visual Acuity — 0.771; 0.861 Decimal Visual Acuity
Phase 4 N=20 Vault Evaluation After ICL Implantation
Nearsightedness
Primary: Mean Difference Between Predicted and Actual Central Vault at 1-month After ICL Implantation — 0.170 Milimeters
N/A N=350 Clinical Investigation of the Clareon® Intraocular Lens (IOL)
Cataract
Primary: Percentage of All-implanted Subjects Achieving Monocular Best Corrected Distance Visual Acuity (BCDVA) of 0.3 logMAR or Better at Month 12 Postoperative — 99.7…
N/A N=299 Clinical Investigation of a New Intraocular Lens
Cataract
Primary: Distance Corrected Intermediate Visual Acuity — 0.105; 0.343 LogMAR
N/A N=272 Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
Cataract · Corneal Astigmatism
Primary: Distance-Corrected Near Visual Acuity (DCNVA) at 40 cm — 0.104; 0.522 LogMAR — p=<0.0001