Phase 4 N=132 Presbyopia-Correcting Intraocular Lenses (IOLs)
Cataract
Primary: Best Corrected Visual Acuity — -0.075; -0.080; -0.081; 0.227 logMAR
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Phase 4 N=93 Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
Cataract
Primary: Monocular Mesopic Contrast Sensitivity Without Glare (1.5, 3 Cycles/Degree) — 1.612; 1.582; 1.527; 1.658 log contrast sensitivity units
N/A N=229 Toric Intraocular Lens Following Cataract Surgery
Cataract · Astigmatism
Primary: Percent Reduction in Absolute Cylinder — 84.975; 46.498 percentage of intended cylinder reduct
Phase 4 N=78 Evaluation of 3 Intraocular Lenses Following Lens Extraction
Cataract
Primary: Mesopic Monocular Contrast Sensitivity Without Glare 1.5 and 3 Cycles/Degree — 1.494; 1.576; 1.410; 1.613 log contrast sensitivity units
N/A N=193 Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
Aphakia
Primary: Percentage of Subjects Not Bothered at All by Halos (QUVID Question 2.3) — 88.7; 58.1; 58.6 percentage of subjects
N/A N=32 Clinical Investigation of an AcrySof IQ PanOptix Toric Intraocular Lens
Aphakia · Corneal Astigmatism
Primary: Percentage of Eyes With ≤ 0.25 Diopter (D) Absolute Refractive Cylinder at Visit 3/3A (Day 30-60) — 90.2 percentage of eyes — p=<0.0001
N/A N=15 ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)
Bilateral Cataract
Primary: Number of Subjects Reporting Spatial Distortions Related to Intraocular Lens (IOL) Misalignment — 11; 2 Participants
N/A N=175 Clareon Toric vs Eyhance Toric
Cataract · Aphakia
Primary: Mean Binocular Best-corrected Distance Visual Acuity (BCDVA) at 4 Meters Under Bright Lighting Conditions — -0.100; -0.055 logMAR
N/A N=218 Clinical Investigation of the Next Generation Intraocular Lens
Cataract
Primary: Monocular, Photopic Distance Corrected Intermediate Visual Acuity (DCIVA) at 66 Centimeter (cm) — 0.053; 0.370 logMAR — p=< 0.0001
Phase 4 N=100 Clinical Investigation of the Bi Flex M Multifocal IOL
Cataract
Primary: Long Term Monocular Visual Acuity (VA) — 0.192; 0.205; 0.614; 0.319 LogMAR
N/A N=39 Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes
Cataract Bilateral · Presbyopia
Primary: Binocular Uncorrected Near (40 cm) Visual Acuity. — 0.13 logMAR
Phase 4 N=280 ACRYSOF® ReSTOR® Aspheric +3.0 D Add Power Intraocular Lens (IOL)
Cataract
Primary: Binocular Distance Corrected Near Visual Acuity at Best Distance (That Which Provides the Subject With the Best Vision) — 0.07; 0.09 logMAR
N/A N=500 RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study
Aphakia · Cataract
Primary: Absolute Manifest Refraction Spherical Equivalent (MRSE) Compared Between the Two Study Groups, LAL and Control — 0.210; 0.345 Diopters
N/A N=448 Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
Refractive Errors · Myopia · Myopic Astigmatism
Primary: Unaided Visual Acuity After the Procedure — 0.264; 0.227 LogMar vision
Phase 3 N=122 One-Piece Hydrophobic Acrylic Intraocular Lens in Subjects Undergoing Cataract Extraction
Aphakia · Cataract
Primary: Visual Acuity — 108 Participants
Phase 3 N=269 Clinical Evaluation of a 1-Piece Intraocular Lens
Cataract
Primary: Mean Percent Reduction in Cylinder — 32; 75; 76. percentage of reduction in cylinder — p=<0.0001
N/A N=64 AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
Cataracts
Primary: Uncorrected Decimal VA (5 m) — 48; 3; 1; 0 participants
N/A N=74 Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
Cataracts
Primary: Percentage of Eyes Achieving a Manifest Refraction Spherical Equivalent (MRSE) Within ± 0.50 D of the Intended Adjustment Target — 78.3; 80.0; 79.2 percentage of eyes
N/A N=65 AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL) Clinical Study in Japan
Cataracts
Primary: Monocular Uncorrected Distance Decimal Visual Acuity — 3; 3; 1; 0 participants
Phase 4 N=76 Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
Cataract
Primary: Visual Acuity — 0.54; 0.06; 0.03; 0.04 logMAR
N/A N=220 A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)
Cataract
Primary: Monocular Photopic Distance Corrected Intermediate Visual Acuity (DCIVA) [(Logarithm of the Minimum Angle of Resolution (logMAR)] 66 Centimeters (cm) From Spectacle…
N/A N=191 Hydrophobic Acrylic Toric IOL Designed to Reduce the Effects of Preoperative Corneal Astigmatism
Astigmatism
Primary: Mean Dioptric Change in Cylinder — -0.479; -0.865; -1.413; -1.944 diopter
N/A N=272 Clinical Investigation of the Safety and Effectiveness of an Investigational Model of the TECNIS® Intraocular Lens
Cataract · Corneal Astigmatism
Primary: Distance-Corrected Near Visual Acuity (DCNVA) at 40 cm — 0.104; 0.522 LogMAR — p=<0.0001
N/A N=600 Calhoun Vision Light Adjustable Lens (LAL) in Subjects With Pre-Existing Corneal Astigmatism
Cataract
Primary: Percent Reduction in Manifest Cylinder — 74.6; 19.9 percent reduction in manifest cylinder
N/A N=9 Early Feasibility Study Using IOPCL MAG to Improve Near Vision in ARMD Subjects
Low Vision · Age Related Macular Degeneration
Primary: Tilt of the PCIOL and IOPCL MAG Complex — 9; 9 Eyes
Phase 4 N=20 Vault Evaluation After ICL Implantation
Nearsightedness
Primary: Mean Difference Between Predicted and Actual Central Vault at 1-month After ICL Implantation — 0.170 Milimeters
N/A N=25 Influence of Lens Design on Particulate Exchange in the Post-lens Tear Film
Visual Acuity
Primary: Microsphere Clearance Rate — 96.9; 98.1; 99.4; 96.6 percent clearance
Phase 4 N=26 Low Cylinder Toric
Cataracts
Primary: Uncorrected Distance Visual Acuity — 0.09 logMAR
Phase 3 N=250 Safety and Efficacy of a Violet Visible Light Blocking Intraocular Lens (IOL)
Cataract
Primary: Best Corrected Distance Visual Acuity — 119; 120 participants
Phase 4 N=20 Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof
Cataract
Primary: Best Corrected logMAR Contrast Acuity at Photopic/Mesopic Condition — 0.34; 0.34 log MAR