Phase 2 N=15 Metformin to Augment Low Milk Supply (MALMS) Study
Low Milk Supply · Pre-diabetes · Insulin Resistance
Primary: Peak Change in Milk Output — 8; -58 milliliters
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=250 A Mobile, Semi-automated Text Message-based Intervention to Prevent Perceived Low or Insufficient Milk Supply
Breast Feeding
Primary: Perception of Milk Supply — 54.9; 56.2 score on a scale — p=.272
N/A N=180 Early Initiation of Milk Expression in Mothers of Very Low Birth Weight Infants
Breast Milk Expression
Primary: Pumped Milk Volume Day 1 — 3; 4; 5 mL — p=0.015
Phase 2 N=21 The Safety and Efficacy of Recombinant Human Prolactin
Healthy
Primary: Galactorrhea — 0; 56 percentage of participants
N/A N=52 Milk in Life Conditions (MiLC): Bacterial Composition of Human Milk Pumped and Stored in "Real-Life" Conditions
Human Milk Microbiome · Bacterial Growth
Primary: Bacterial Community Richness — 64.2; 58.9; 64.0; 60.8 Observed taxa — p=0.9
Phase 3 N=483 Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants
Infant, Newborn · Infant, Small for Gestational Age · Infant, Extremely Low Birth Weight
Primary: Bayley Scales of Infant Development (BSID) Cognitive Composite Score — 80.7; 81.1 Score on a scale
N/A N=155 Immediate Postpartum Contraceptive Implant Placement and Breastfeeding Success in Women at Risk for Low Milk Supply: A Non-inferiority Trial
Contraception · Breastfeeding · Postpartum Contraception
Primary: Number of Participants Breastfeeding at 6 Months — 6; 4; 6 Participants
Phase 2 N=90 Enhancing Breast Milk Production With Domperidone in Mothers of Preterm Neonates
Low Milk Supply
Primary: Increase in Breast Milk Production — 35; 26 Participants
N/A N=3,188 Low-birthweight Infant Feeding Exploration
Low Birthweight · Pre-Term
Primary: Length-for-Age Z-score — -1.43 Z-score
N/A N=74 Prenatal Breast Pump Education of Mothers and Their Support Person
Preterm Birth · Breast Feeding
Primary: Onset of Lactogenesis Stage II Through Volume Attainment — 84.8; 81 hours — p=0.985
N/A N=22 Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
Osteoporosis
Primary: Change in Bone Mineral Density (BMD) in HIP at 6 Months — -0.041; 0.011 grams/cm^2
N/A N=243 Prenatal Interventions to Promote Exclusive Breastfeeding
Breastfeeding · Intention · Health Behavior
Primary: Number of Participants Who Intended to Exclusively Breastfeed Post-intervention — 40; 36; 86; 67 Participants
N/A N=442 Home Based Peer Support Program for Mothers With Low Breastfeeding Self-efficacy
Breastfeeding
Primary: Infant Feeding Status: Exclusive Breastfeeding — 46; 39 Participants
Phase 2 N=27 DHA Supplementation for Lactating Mothers
Docosohexaenoic Acid Supplementation of Mothers to
Primary: Infant Serum Soluble Receptor for AGE (sRAGE) Levels at 4 Weeks From Baseline From Mothers Supplemented With 200 or 1000 mg/kg Per Day of DHA — 900; 1127 pg/mL
N/A N=280 PRenatal Video-Based Education and PostPARtum Effects
Breastfeeding
Primary: Breastfeeding Exclusivity — 67; 84 Participants — p=.1200
N/A N=117 Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk
Infant, Very Low Birth Weight
Primary: Intestinal Microbiome Diversity — 55.7; 46.3 taxa represented
N/A N=22 Cold Milk for Dysphagia in Preterm Infants
Dysphagia of Newborn
Primary: Percentage of Infants With Improvement of Dysphagia — 58 Percentage of patients
N/A N=2,108 The Impact of Telelactation Services on Breastfeeding Outcomes
Breastfeeding
Primary: Breastfeeding Duration 1 — 674; 639 Participants — p=0.08
N/A N=14 Multisensory Early Oral Administration of Human Milk in Preterm Infants
Infant Development · Stress
Primary: Feasibility of Intervention — 0; 7 Participants
N/A N=31 Breastfeeding and Exercise for Healthy Infants and Postpartum Moms Too!
Osteoporosis · Obesity · Weight Loss
Primary: Bone Mineral Density-Total Body — -0.3; -1.1 percent change in BMD (g/cm2) — p=<0.05
N/A N=130 Maternal Role in Oral Feed Establishment in Preterm Neonates
Preterm Birth · Tube Feeding · Swallowing Disorder
Primary: Transition Time to Full Oral Feeding — 10; 9 days
N/A N=1,296 Breast for Success: A Family-Centered Intervention in Support of Breastfeeding Among High-risk Low-income Mothers
Breastfeeding
Primary: Program Feasibility- Feeding Outcome Collected — 287; 288; 314 participants
N/A N=1,411 Comparison of Breast Feeding Counseling and Video Demonstration on Exclusive Breast Feeding Rates at 6 Weeks
Exclusive Breast Feeding
Primary: Exclusive Breast Feeding Rate at Six Weeks Postnatal Age — 271; 117; 97 Participants
Phase 2 N=69 Cabergoline for Lactation Inhibition After Early Second-Trimester Abortion or Pregnancy Loss
Lactation Suppressed
Primary: Number of Participants Reporting Breast Pain — 16; 30 Participants
N/A N=38 Feeding and Wellness Among Late Preterm Infants
Late Preterm Infant
Primary: Phone Call Completion Rate — 194; 102; 59; 52 calls
N/A N=250 Promoting Self-Management of Breast and Nipple Pain With Technology (PROMPT) for Breastfeeding Women Study
Breastfeeding, Exclusive · Pain, Acute · Maternal Distress
Primary: Visual Analogue Scale for Breast and Nipple Pain Severity — 39.43; 36.55; 44.31; 36.93 units on a scale — p=<0.0045
Phase 4 N=30 Progestin-Only Pill Use and Breastfeeding Study
Contraception · Breastfeeding
Primary: Exclusive Lactation Among Birthing People at 8 Weeks Postpartum. — 7; 7; 6 Participants
Phase 2 N=73 Cabergoline for Lactation Inhibition After Second-Trimester Abortion or Loss
Lactation Suppressed
Primary: Number of Participants Reporting Breast Pain — 10; 32 Participants
N/A N=100 Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Malnutrition · Wasting · Growth Failure
Primary: Change in Body Weight — 365; 2.5; -470; 2.5 g
N/A N=168 BOOST: Breastfeeding Onset and Onward With Support Tools
Breastfeeding Duration
Primary: Number of Participants Breastfeeding Their Infants at 1 Month — 76; 74 Participants