N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
N/A N=11 Personalizing MPK Prescription
Transfemoral Amputation
Primary: Ten Meter Walking Test — 0.9963; 1.1051; 1.1111 Meters per second — p=0.126
N/A N=30 Investigating Outcomes of Lower Limb Trauma
Trauma
Primary: Functional Outcome (Consisting of Questionnaire Score, Hamlyn Mobility Score (HMS) Gait/Activities of Daily Living Parameters) — 19.7; 58.2 units on a scale
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
Phase 3 N=10 Southern Bone & Joint Study - Brimless Sockets
Socket Designs of Transfemoral Amputees.
Primary: Gait
N/A N=23 Falls in Older Persons With Limb Loss
Amputation · Elderly
Primary: Foot's Height During the Swing Phase of Walking (i.e., Foot Clearance) Measured in Centimeter — 6.1; 5.5; 6.1; 5.7 cm
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
Phase 2 N=25 Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
Anterior Cruciate Ligament Reconstruction
Primary: Cross-sectional Area of Skeletal Muscle Fibers (All Fibers) — 2827; 3318; 2206; 2376 micrometer squared — p=<0.05
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=358 Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia
Critical Lower Limb Ischemia
Primary: Late Lumen Loss (LLL) of the Target Lesion by Quantitative Vascular Angiography (QVA) — 0.605; 0.616 mm
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=44 Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program
Traumatic Amputation
Primary: Lower Extremity Muscle Strength- Extension — 24.5; 26.4; 27.6; 34.1 Kilograms — p=<0.05
N/A N=40 Skin to Adductor Canal Distance in Various Positions
Knee Arthritis
Primary: Skin to Adductor Canal Distance Disparity — 1.01; 0.28; 0.43; 0.63 centimeters
N/A N=5 Transfemoral Socket Design and Muscle Function
Amputation
Primary: Residual Limb Hip Muscle Peak Torque at Baseline — 25.6; 14.9; 25.6; 13.1 newton-meters / kg*meters
Phase 4 N=111 The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)
Osteoarthritis
Primary: Time to Meet Physical Therapy Discharge Criteria — 2109.3; 1883.1 Minutes
N/A N=11 Clinical Investigation (Beta) of a New Developed Prosthetic Knee
Amputation
Primary: Satisfaction on Ramp Descent With the New Microprocessor-controlled Prosthetic Knee (MPK) — 1; 0; 3; 4 Participants
N/A N=73 Total Knee Replacement With Tourniquet or Aquamantys
Knee Replacement
Primary: Isometric Quadriceps Strength — 11.58; 9.60 Nm/kg
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
N/A N=25 Comparative Outcomes Assessment of the C-Leg With a New Knee Prosthesis
Other and Unspecified Complications of Amputation Stump
Primary: 75 Meter Self Selected Walking Test — 65.1; 64.0; 54.0 seconds
N/A N=50 Comparative Effectiveness Between Microprocessor Knees and Non-Microprocessor Knees
Lower Limb Amputation Above Knee (Injury)
Primary: Daily Activity Measured With Triaxial Accelerometers — 15.64; 19.68; 18.23 % of Day — p=0.01
N/A N=10 Intent Recognition for Prosthesis Control
Amputation
Primary: Overground Self-selected Walking Speed — 0.695 Meters per second
Early Phase 1 N=33 N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes
Diabetes Mellitus · Critical Limb Ischemia · Lower Limb Amputation Knee
Primary: Change in Postoperative Laser-Assisted Fluorescent Angiography (LAFA) Perfusion. — 0.060; 0.096; 0.045; 0.031 percentage of defect
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
Phase 4 N=62 Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
Pain, Postoperative · Total Knee Arthroplasty (TKA)
Primary: Time to Achieve Physical Therapy Discharge Criteria as Measured by 75-feet Walk Test. {Number of Hours After Conclusion of Surgery} — 67.3; 66; 46.5 Hours — p=0.355
N/A N=17 Clinical Investigation (Beta) of Power Knee Mainstream - Dynamic
Prosthesis User · Amputation
Primary: Mean Difference in Borg Category Rating Scale Before and After 6MWT at 2 Weeks — 3.4; 2.8; 3.1; 2.5 score on a scale
N/A N=26 Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback
Arthropathy of Knee Joint
Primary: Weight-bearing Ratio During Five Times Sit-to-Stand Test (FTSST) — 0.77; 0.8 ratio — p==0.329