Phase 4 N=13 Milnacipran for Lumbosacral Radicular Pain
Radicular Pain Related to Lumbosacral Disc Disease
Primary: Visual Analogue Scale Score Referring to Radicular Pain (VAS-rad) — 58.7; 67.7; 13.6; 59.7 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=149 Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain
Lumbosacral Radiculopathy
Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
Phase 3 N=84 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy
Lumbosacral Radiculopathy
Primary: Numerical Rating Leg Pain Score — 2.54; 3.56; 3.78 units on a scale
Phase 4 N=39 Efficacy of Pregabalin in Patients With Radicular Pain
Neuropathy; Radicular, Lumbar, Lumbosacral · Failed Back Surgery Syndrome · Spinal Stenosis
Primary: Pain Scores (NRS) at 3-weeks — 6; 3 units on a scale — p=0.279
N/A N=51 Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization
Radiculopathy
Primary: Visual Analog Scale — 5.638; 5.050; 5.094; 4.894 Centimeters
Phase 4 N=29 Lumbar Stenosis Outcomes Research (LUSTOR)
Lumbar Spinal Stenosis
Primary: Time to First Symptoms of Moderate Pain — 2.52; 3.06 minutes
N/A N=31 Assess the Effectiveness of Pulse RadioFrequency in Patients With Chronic Lumbar Radicular Pain
Chronic Pain · Back Pain
Primary: Recruitment Rate — 32 Participants
N/A N=145 Steroids Versus Gabapentin
Sciatica · Radiculopathy
Primary: Average Leg Pain at 1 Month Measured Using the Numeric Pain Scale — 3.3; 3.7 units on a scale
N/A N=48 Additional Gluteal Control Training for Low Back Pain With Functional Leg Length Inequality
Low Back Pain, Recurrent
Primary: Leg Length Inequality — 0.3; 0.58 centemeter
Phase 4 N=79 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Radicular; Neuropathic, Cervical · Neck Pain
Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23
Phase 3 N=82 A Trial of Corticosteroids for Low Back Pain
Radicular Low Back Pain
Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale
Phase 1 N=26 A Two-part Proof-of-Concept Study Assessing the Safety and Efficacy of LAT8881 in Lumbar Radicular Pain
Radiculopathy Lumbar
Primary: The Number of Participants With Adverse Events by Dose (Part A) — 1; 1; 2; 2 participants
N/A N=158 Central Nervous System Amplification in Lumbar Failed Back Surgery Syndrome
Chronic Pain
Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change
N/A N=196 Efficacy of Acupuncture for Lumbar Spinal Stenosis
Lumbar Spinal Stenosis · Intermittent Claudication
Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale
N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
N/A N=20 Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
Radiculopathy · Lower Extremity Radicular Pain
Primary: Pre-epidural Warm Sensation Quantitative Sensory Testing (QST) Results — 2.68; 5.67 Degrees Celsius — p=.04
N/A N=39 A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Lumbar Facet Syndrome
Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants
N/A N=120 Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Low Back Pain
Primary: Numeric Pain Rating Score — 7.9; 8.1; 4.9; 3.4 units on a scale — p=<0.001
N/A N=331 PROs in Chronic Low Back Pain Patients With Accompanying Lower Limb Pain (Neuropathic Component) Treated With Pregabalin
Low-Back Pain
Primary: Change From Baseline in Pain Related Sleep Interference Scale (PRSIS - Past Week Recall) — 3.1; 2.9; -1.306; -0.357 scores on a scale — p=<0.001
N/A N=42 Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
Low Back Pain · Sciatica · Back Related Leg Pain
Primary: Number of Particpants Screened Per Month — 103 participants per month
N/A N=416 Flares of Low Back Pain With Activity Research Study
Low Back Pain
Primary: Participant-reported "Flares" of Low Back Pain (Aim 1) — 7.3 Mean flares per year
Phase 4 N=35 True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
Low Back Pain
Primary: Change in McGill Pain Questionnaire - Short Form — -0.73; -3.78 units on a scale
N/A N=40 Effect of Peripheral Magnetic Stimulation in Patients With Chronic Lower Back Pain
Low Back Pain
Primary: Oswestry Disability Index (ODI) — 15.1; 15.0; 13.7; 4.6 Scores on a scale
Phase 4 N=100 RCT Superior Hypogastric Block During LH
Hysterectomy
Primary: Postoperative Pain Scores — 3.9; 4.7 score on a scale
Phase 4 N=83 Lumbar Plexus Block for Postoperative Pain Control After Hip Arthroscopy. A Randomized Controlled Trial
Postoperative Pain
Primary: Numeric Rating Scale (NRS) Pain at Rest (0-10) on Day of Surgery Prior to Discharge — 3.3; 4.2 units on a scale
N/A N=10 Pain and Sensation After Regional Anesthesia - Pilot Study
Anesthesia, Conduction · Osteoarthritis, Hip
Primary: Patient Pain Score With Activity — 1.4 units on a scale
N/A N=30 Effectiveness of the Compression Belt for Patients With Sacroiliac Joint Pain
Low Back Pain
Primary: Oswestry Low Back Pain Questionnaire — 26.00; 24.40; 17.20; 14.67 units on a scale
N/A N=46 Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy
Pain
Primary: Postoperative Gluteal Pain — 3.6; 4.0; 2.0; 2.0 units on a scale — p=0.83
Phase 4 N=400 Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)
Spinal Stenosis · Low Back Pain
Primary: Roland Morris — 11.8; 12.5 units on a scale