N/A N=20 Hybrid Cochlear Implants in Severe to Profound Adults, Children, and Adolescents
Hearing Loss, High-Frequency
Primary: Change in CNC Word Perception — 27.6; 34; 55.9; 68 percentage of words correct
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=24 Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
Hearing Loss · Ear Diseases · Hearing Disorders
Primary: Change in Consonant Nucleus-Consonant (CNC) Word Recognition Test (Implanted Ear Only) — 2.13; 61.14 percentage of recognized words
N/A N=40 Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial
Hearing Loss
Primary: Change in Poor Ear Alone CNC Monosyllabic Word Understanding in Quiet — 0.09; 0.53; 0.44 percentage of words correct — p=<0.001
Phase 4 N=25 Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Hearing Loss · Depression
Primary: Hamilton Rating Score for Depression (HRSD) — 12.04; 13.86 score on a scale
N/A N=107 Sensory Integration of Auditory and Visual Cues in Diverse Contexts
Vestibular Disorder · Hearing Loss, Sensorineural
Primary: Root Mean Square Velocity Anterior-posterior [AP] in cm/s (RMSV) — 3.59; 3.30; 3.07 cm/s — p=0.005
N/A N=276 Evaluation of Unilateral vs Bilateral Hearing Aids for the Treatment of Age-related Hearing Loss
Hearing Loss
Primary: Change in Hearing Aid Benefit as Measured by Abbreviated Profile of Hearing Aid Benefit (APHAB) — -19.74; -14.41 score on a scale — p=0.003
N/A N=37 Use of Amplification in Children With Unilateral Hearing Loss
Unilateral Hearing Loss
Primary: HEAR-QL 26 Questionnaire — 69.61; 74.05; 71.04; 80.21 score on a scale
N/A N=10 Benefit of Assistive Listening Device for Lateralization
Hearing Loss, Sensorineural
Primary: Lateralization Hearing Ability — 71; 54 percent correct responses — p=<.05
N/A N=50 Safety and Efficacy of the Vibrant Soundbridge (VSB) for Mixed and Conductive Hearing Losses
Hearing Loss
Primary: Speech Perception in Quiet (Monosyllables) in Patients Implanted With Vibrant Soundbridge — 94.12 percentage of words correct
N/A N=290 Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes
Presbycusis
Primary: Hearing Aid Use Measured Using In-situ Glasgow Hearing Aid Benefit Profile (EMA-GHABP-Use) — 4.4; 4.1; 3.8; 4.5 score on a scale
N/A N=20 Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss
Hearing Loss, Unilateral
Primary: Change Over Time in the Ability to Perceive Single Words as Assessed by Consonant-Nucleus-Consonant (CNC) Word Recognition Testing — 1.4; 14.4; 28.2; 45.0 percentage of…
N/A N=10 Cochlear Implantation After Labyrinthectomy or a Translabyrinthine Surgical Approach
Unilateral Acoustic Neuroma · Meniere's Disease
Primary: Change in Consonant-Nucleus-Consonant (CNC) Words Scores Over Time — 23.6; 22; 18.8; 42.7 Percentage of words correct
N/A N=50 Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System
Sensorineural Hearing Loss
Primary: Consonant Nucleus Consonant (CNC) Monosyllabic Word Score-Treated Ear (CO-PRIMARY) — 65.4 percentage of words correct
Phase 2 N=72 Micronutrients to Prevent Noise-induced Hearing Loss
Noise-Induced Hearing Loss
Primary: Average Threshold Shift at 4 kHz in Both Ears — 3.94; 3.4; 2.77; 2.03 decibels — p=0.58
Phase 4 N=32 Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System
Hearing Loss
Primary: Comparison of Pre-implant Consonant-Nucleus-Consonant (CNC) Scores to Post-implant CNC Scores in Bilateral Users. — 4.0; 69.0 percent of words correct
Phase 2 N=23 FX-322 in Sensorineural Hearing Loss
Sensorineural Hearing Loss
Primary: Number of Participants With Treatment-emergent Adverse Event(s) (TEAEs) — 2; 3; 5; 6 Participants
N/A N=151 Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions
Age-related Hearing Impairment 1 · Personal Communication
Primary: Change From Baseline in Hearing Handicap Inventory for the Elderly (HHIE-S) — -13.2; .06 score on a scale
N/A N=45 Interaural Frequency and Loudness Mismatch in SSD CI Users
Outcomes
Primary: Speech Understanding in Noise, Measured With the R-Space Test Environment. The R-Space Test Environment Simulates Speech Understanding in a Noisy Restaurant. — -3.0…
N/A N=20 Effect of Hearing Aid Labeling on Speech Understanding Measures
Hearing Loss
Primary: Quick Speech in Noise Test (QuickSIN) — 6.2; 9.6; 5.2; 10 decibels (dB) — p=>.05
Phase 2 N=142 FX-322 in Adults With Acquired Sensorineural Hearing Loss
Hearing Loss, Sensorineural · Noise Induced Hearing Loss · Sudden Hearing Loss
Primary: Word Recognition in Quiet — 14.7; 11.1 Percent of subjects — p=0.525
N/A N=27 Audiobooks for Hearing Loss App as Auditory Training
Hearing Loss · Hearing Impaired Children · Hearing Impairment
Primary: Audiobooks Efficacy: Change in Slope of Curve for SNR Loss Scores on a Scale/Week for Partial BKB-SIN Hearing Test — 5.978; 5.889; 5.757; 5.600 units on a scale/week…
N/A N=34 Longitudinal Outcomes of Hearing Aids
Presbycusis
Primary: Hearing Aid Benefit as Measured by the Glasgow Hearing Aid Benefit Profile (GHABP) — 3.68; 3.55; 3.63 score on a scale
N/A N=67 Dual-Task Cost in Bilateral Hearing Loss
Bilateral Hearing Loss · Healthy Aging
Primary: Gait Speed (Single Task) Over 1-minute Walk — 1.14; 1.02; 1.1 m/sec — p=<0.05
N/A N=10 Benefits of Assistive Listening Device for Speech Intelligibility
Hearing Loss
Primary: Speech Intelligibility in Noise — 58; 80; 27; 50 percentage of words correctly repeated — p=<0.01
N/A N=27 Hearing Aid Signal Processing Comparative Study
Hearing Loss, Sensorineural
Primary: Standardized Validated Questionnaire Measuring Hearing Aid Sound Quality for First Study Set Worn, i.e. Study Set A for Arm A-B-A and Study Set B for Arm B-A-B — 7.16…
N/A N=11 Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants
Implants, Cochlear · Child · Hearing Loss, Bilateral
Primary: The Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS) — 0; 53; 64; 75 percentage out of 40
N/A N=11 Audiovestibular Function in Infratentorial Superficial Siderosis
Siderosis · Neurological Disorder · Rare Diseases
Primary: Hearing Evaluation - Pure Tone Audiometry — 57.3 decibel hearing level
N/A N=99 Approaches to Auditory Rehabilitation for Mild Traumatic Brain Injury
Traumatic Brain Injury
Primary: Competence Score From the Psychosocial Impact of Assistive Devices Scale (PIADS) — 0.56; .37; .62; .41 units on a scale — p=0.527
N/A N=26 Effects of Remote Microphone Hearing Aids on Children With Auditory Processing Disorder
Auditory Processing Disorder
Primary: Listening Inventory For Education Revised (LIFE-R) - Total Score — 30.91; 28.30; 33.33; 35.61 Units on a scale
Phase 2 N=135 Clinical Trial of the "Living Well With Hearing Loss Workshop"
Hearing Loss · Stress
Primary: Communication Profile for Hearing Impaired: Maladaptive Strategies Subscale — 0.33; 0.37 score on a scale — p=0.69