30 closest matches · ranked by relevance
Diabetic Neuropathy, Painful
Primary: Change From Week 8 to Week 16 Endpoint in 24 Hour Average Pain Item Score on the Brief Pain Inventory (BPI) Modified Short Form — -2.353; -2.161 units on a scale — p=0.370
Diabetic Neuropathies
Primary: Change From Baseline to 12 Week Endpoint in Brief Pain Inventory 24-hour Average Pain Score — -2.69; -2.31 units on a scale — p=0.617
Diabetes · Peripheral Neuropathy · Pain
Primary: Change in Spontaneous Pain at 60-120 Minutes After Lidocaine Infusion Initiated (Assessed on 0-10 NRS) — 33; 51 percentage of pain change from baseline — p=0.03
Diabetic Neuropathies · Depressive Disorder, Major
Primary: Change of Brief Pain Inventory (BPI) Average Interference Score From Baseline to Week 12 — -1.4; -2.2 Scores on a scale — p=< 0.0001
Diabetic Neuropathy, Painful
Primary: Change From Baseline to Study Endpoint in Mean Weekly Pain Scores — -1.20; -1.82; -1.94 score on scale — p=0.0075
Diabetic Peripheral Neuropathy
Primary: Mean Change From Baseline to Week 5 in Average Daily Pain Score (ADPS) Following Treatment With DS-5565 Compared to Pregabalin and Placebo — -1.86; -1.79; -2.04; -2.32…
Painful Diabetic Neuropathy
Primary: Change in Average Daily Pain Score From Baseline Week to the Last 4 Weeks of the Maintenance Phase — -1.9; -2.2; -2.4 units on a scale — p==0.0410
Diabetic Peripheral Neuropathy
Primary: Change From Double-Blind Baseline of the Average Pain Intensity Based on an 11-point Numerical Rating Scale(NRS) Over the Last Week of the Maintenance Period at Week 12…
Diabetic Peripheral Neuropathy
Primary: Change in Patient Quality of Life at Baseline and 8 Months — 0.66; 0.65; 0.68; 0.68 units on a scale
Diabetic Neuropathy, Painful
Primary: Mean Change From Baseline to 12 Weeks in Weekly Mean of Daily 24 Hour Average Pain Score, Pregabalin Compared With Duloxetine — -2.12; -2.62 units on a scale — p=0.076
Diabetic Neuropathy, Painful
Primary: Change From Baseline in Weekly Mean 24-hour Average Pain Severity (APS) Score at 5 Weeks — -2.08; -2.22; -2.45; -2.42 units on a scale
Diabetic Neuropathy, Painful
Primary: Mean Change From Baseline at 12-Week Endpoint in the Weekly Mean of Pain Severity Score — -2.40; -1.97 units on a scale — p=0.030
Diabetic Peripheral Neuropathic Pain (DPN) · Postherpetic Neuralgia (PHN) · HIV-related Neuropathic Pain (HIV)
Primary: Change From Baseline to End of Treatment (EOT) in Weekly Mean Pain Score on the Daily Pain Rating Scale (DPRS) — -3.8 scores on scale — p=< 0.0001
Diabetic Peripheral Neuropathic Pain · Diabetic Peripheral Neuropathy
Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…
Diabetic Neuropathy
Primary: Change in Clinic Visit Pain Score at the 12 Week Visit Compared to Baseline as Assessed by the 11-point Likert Numerical Rating Scale (NRS) — 6.2; 6.6; 6.6; 6.5 Scores…
Moderate to Severe Pain Due to Diabetic Polyneuropathy
Primary: Short Form McGill Pain Score. — 49.56; 47.65 units on a scale
Diabetic Neuropathies
Primary: Change From Baseline at Week 12 in Average Pain Severity Rating Using Diaries for the Combined Duloxetine Arms (40 mg + 60 mg) — -1.61; -2.47 units on a scale — p=<0.0001
Diabetic Peripheral Neuropathic Pain
Primary: Change in the Average Daily Pain Score (ADPS) From Baseline to Week 14 Following Administration of DS-5565 in Participants With Diabetic Peripheral Neuropathic Pain…
Diabetic Neuropathies · Neuralgia
Primary: Daily Pain Rating Scale (DPRS)- Mean Pain Score (ITT Population) — 4.63; 5.13 score on scale — p=0.049
Diabetic Peripheral Neuropathic Pain
Primary: Numeric Rating Scale (NRS) Pain Intensity — -0.83; -0.45 units on a scale — p=0.47
Pain · Diabetic Peripheral Neuropathy
Primary: Mean Change in Average Daily Pain Score From Baseline Among Participants Who Received DS5565 for Pain Associated With Diabetic Peripheral Neuropathy — -0.59; -0.71…
Diabetic Neuropathies
Primary: Number of Participants Who Experienced an Adverse Event (AE) — 11; 22; 126; 121 participants
Diabetic Peripheral Neuropathy
Primary: Numeric Rating Scale (NRS) Average Pain Intensity — -1.50; -1.61; -1.15; -1.23 score on a scale
Diabetic Neuropathy, Painful
Primary: Change From Single-Blind Baseline in Mean Pain Score at Week 19 During Double-Blind Phase — 6.8; 6.7; -3.9; -3.5 units on a scale — p=0.1221
Diabetic Neuropathy
Primary: Change From Baseline (at Randomization) in Average Pain Intensity on an 11-point Numerical Rating Scale (NRS) Over the Last Week of the Double-blind Maintenance Period…
Neuropathic Pain
Primary: Change From Baseline to Days 24-28 in Numerical Rating Scale (NRS) Average Pain Score. — -1.35; -1.50; -1.61 Scores on a scale
Diabetic Neuropathy, Painful
Primary: Daily Pain Numeric Rating Scale (NRS) — 6.17; 6.62; 6.35; 5.45 Unit on a scale
Diabetic Peripheral Neuropathic Pain
Primary: Change From Baseline in Average Pain Intensity as Measured by the Numeric Rating Scale (NRS) — -1.50; -1.35 score on a scale
Diabetic Neuropathy, Painful; Diabetic Neuropathies
Primary: Brief Pain Index - Item 5, Average Daily Pain Score (Range 0-10) Higher Values Indicate Worse Pain — 4.24; 4.41; 4.27 Average daily pain score — p=0.5695
Peripheral Neuropathy · Neuropathic Pain
Primary: Change From Baseline in Mean Numeric Pain Rating Scale (NPRS) Score — 1.02; 1.74; 1.51 units on a scale