Clinical Trial Search

Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…

Primary: Maximal Oxygen Uptake — 14.5; 15.1 ml/kg/min

Primary: Percent Change in Forearm Glucose Uptake — -73; 127; -95 Percent change in clamp FGU with immob

Primary: Skeletal Muscle Capillarization — 0.4; 0.2 capillaries per muscle fiber — p=0.27

Primary: Change in Total Lean Mass From Baseline — 322.8; 697.6; 392.4; 548.0 grams lean mass — p=0.45

Primary: Lean Leg Mass — -1.2; -0.9 g

Primary: Protein Anabolism — 3.56; 11.8; 3.02 grams — p=<0.05

Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared

Primary: Resting and Maximum Plasma Leucine Concentration — 659; 755; 721; 95 micromoles per liter

Primary: Fat Mass — 44.71 Kg

Primary: Change in 400 Meter Gait Walk Speed — 0.01; -0.02 meters/second

Primary: Muscle Satellite Cells — 3.2; 3.2; 4.0; 3.8 Number of Pax7+ cells/muscle fiber

Primary: Change From Baseline in Isokinetic Strength — -4.90; -4.73 Newton — p=0.97

Primary: Leg Lean Mass — 0.35; -0.55; -0.80; -0.44 kg — p=<0.01

Primary: Change From Baseline in Participant Lean Body Mass — 1.26; 0.29 kg

Primary: Change in Lean Mass Measured by DXA — -2.9; -2.3 Kg

Primary: Change in 1-repetition Maximum (RM) Muscle Strength (Leg Press, Paretic Side) — 126.1; 11.3 lbs

Primary: Change in Expanded Short Physical Performance Battery Score — 0.06; 0.11; 0.16 score on a scale — p=0.16

Primary: Change in Plasma Concentration of Antibodies to Pertussis Antigen (1 Week Post-vaccine) — 63.1; 63.2 units per ml — p=>0.05

Primary: Percent Change in Myofiber Cross Sectional Area (CSA). — -15.1; -13.4 percent change from baseline

Primary: Lean Mass — 403 grams

Primary: Blood Inflammatory Marker — 2.6; 1.8; 2.9; 1.7 mg·L^-1

Primary: Whole-Muscle Protein Synthesis — 0.004; 0.015 %/hr

Primary: Brachial Artery Vascular Function — 5.1; 3.1; 4.4 percent vasodilation

Primary: Double Leg Press Peak Power at 70% — 260.3; 255.6; 251.1; 264.8 Watts

Primary: MRI Quadriceps Involved Leg — 43.87; 38.31 AU — p=.03

Primary: The Dose of Potassium Bicarbonate Needed for Maximal Suppression of 24-hr Urinary N-telopeptide — 240; 230; 241; -53 nmol/day

Primary: Impact of LCS on the Change of Gut Microbiota — 0.023577513; 0.248239465; 0.003810442; 0.10325558 % of total Bacteria — p=<0.05

Primary: Change From Baseline in Body Composition (Lean Body Mass) — 54.93; 57.58; -1.27; -0.60 Kilogram — p=0.1497

Primary: HF Muscle Force — 23.9; 30.9 Newtons (N)