N/A N=50 Treatment of Nasal Airway Obstruction Using the Aerin Medical Device
Nasal Obstruction
Primary: Improvement in NOSE Score — 54.8 units on a scale — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=36 A New Treatment for Mechanical Nasal Obstruction
Nasal Obstruction
Primary: Change in Peak Nasal Inspiratory Flow (PNIF) — 28; 24; 13; 27 liters per minute
N/A N=20 Treatment Outcome Using Vivaer Stylus to Treat Nasal Airway Obstruction
Nasal Obstruction
Primary: Change in NOSE Score — -44.5 units on a scale
Phase 4 N=42 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation
Nasal Obstruction
Primary: Nasal Obstruction as Measured by Nasal Obstruction Symptom Evaluation (NOSE) Scores Following Therapy With Treatment (Triamcinolone Acetonide) and Placebo (Ayr Saline…
N/A N=33 InFlux System for Nasal Breathing Improvement
Nasal Airway Obstruction
Primary: Incidence of Unanticipated Serious Adverse Device Effects — 0 events
N/A N=119 Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study
Nasal Airway Obstruction
Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale - 3 Month Responder Rate — 88.3; 42.5 percentage of participants
N/A N=39 Quality of Life Impact of Nasal Airway Treatment With Aerin Medical Device
Nasal Obstruction
Primary: Change From Baseline NOSE Score — 53.3; 48.1; 53.5 units on a scale — p=<0.0001
N/A N=122 Study of the AERin Medical Vivaer® ARC Stylus for Nasal AirWAY Obstruction
Nasal Obstruction
Primary: Change in Nasal Obstructive Symptom Evaluation (NOSE) Scores From Baseline to 3 Months — -47.6 score on a scale
N/A N=2 Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
Sleep Apnea, Obstructive · Hypotonia · Child, Only
Primary: Ability to Tolerate Measured by Percent of Participants With Protocol Goal — 50 percent of participants
N/A N=32 A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring
Obstructive Sleep Apnea · Snoring
Primary: Apnea-Hypopnea Index (AHI) — 30.0 events/hour — p=0.0559
N/A N=133 Mechanisms of Upper Airway Obstruction
Obstructive Sleep Apnea
Primary: Pharyngeal Critical Pressure (Pcrit) — 1.26; -1.42; -1.06 cm H2O — p=.80
N/A N=55 Nasotracheal Intubation Using Shikani Optical Stylet
Intubation; Difficult
Primary: Number of the Patients With Successful Nasotracheal Intubation — 35; 18 participants
N/A N=32 High Flow Nasal Cannula for Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Apnea Hypopnea Index — 6.15; 14.85 events per hour — p=<0.001
Phase 4 N=50 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction
Nasal Obstruction Present Finding
Primary: Effectiveness of Oxymetazoline in the Treatment of Rhinitis With Persistent Nasal Obstruction — 1.38; 1.67 units on a scale
N/A N=31 High Velocity Nasal Insufflation (Hi-VNI) Use in Upper Airway Surgery
Upper Airway Surgery
Primary: Surgical Case Completion Rate Using HVNI With or Without Converting to Alternative Mode of Oxygenation — 19; 7; 5 Participants
Phase 3 N=323 Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety
Bilateral Nasal Polyposis
Primary: Change in 7-day Average Instantaneous Morning Diary Congestion/Obstruction Symptoms — -0.26; -0.53; -0.56; -0.67 units on a scale
N/A N=94 Barrow Nasal Inventory Survey
Pituitary Tumors
Primary: Change in Mean Survey Response From Baseline to 90 Days Post Surgery — 17.3; 13.5 units on a scale — p=0.001
N/A N=26 Effect of Added Varnum Mouthpiece on Pharyngeal Collapsibility and Sleep Apnea Severity in Mouth Breathers.
Obstructive Sleep Apnea
Primary: Sleep Apnea Severity as Measured by Apnea-hypopnea Index (AHI) — 16.4; 15.8 Events/hour
N/A N=15 Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea Syndrome
Primary: Delta of Apnea Hypopnea Index (AHI) as Measured by Polysomnography (PSG) — 4.27 events per hour
Phase 4 N=34 Nasonex (Mometasone Furoate Nasal Spray) in Adenoids Hypertrophy in Children (P04367)
Adenoids
Primary: Severity of Nasal Obstruction Symptoms at Baseline and Week 12 as Measured by the Total Clinical Score — 3.89; 1.26 Score on a scale
Phase 4 N=64 Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
Allergic Rhinitis
Primary: Total Nasal Congestion Symptom Score — 94; 70; 75; 68 units on a scale
Phase 2 N=140 A Pivotal Subjective Sleep Study of a Nasal Dilator (Breathe Right Tan)
Congestion, Nasal
Primary: Change From Baseline in Mean Total Score of the Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) for Each Domain (Sleep, Sleep Time, Symptoms on…
N/A N=10 Acupuncture for Nasal Congestion in Allergic Rhinitis
Allergic Rhinitis
Primary: Change in Visual Analog Scale (VAS) From Baseline to 6 Weeks (6-week Value Compared to Baseline Value) — -8; -2 Scale points
Phase 2 N=130 A Pivotal Study to Assess the Effectiveness of Nasal Dilator (Breathe Right Nasal Strips)
Congestion, Nasal
Primary: Change From Baseline in Mean Average Score of Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) for Each Domain Problems (Sleep, Sleep Time, Symptoms…
N/A N=174 Comparison of Oxygenation and Ventilation With a Novel Nasal Mask Versus Standard of Care During Colonoscopy
Colonoscopy · Oxygenation · Ventilation
Primary: Time to First Intervention — 10; 19 minutes
Phase 3 N=18 Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Chronic Sinusitis · Polyposis
Primary: Olfaction — 20.2; 19.8 units on a scale
Phase 3 N=34 Montelukast and Inhaled Nasal Steroid Tx in Adult Obstructive Sleep Apnea (OSA)
Obstructive Sleep Apnea
Primary: Number of Participants With a Decrease in the Number of Apnea and/or Hypopnea Events to <5 Per Hour of Sleep — 5; 3 Participants — p==0.946
N/A N=317 Obstructive Sleep Apnea in World Trade Center Responders
Obstructive Sleep Apnea
Primary: Adherence to CPAP Pre-crossover — 1; 0.89 Hours/night
N/A N=60 Nasopharyngeal Versus Nasal Cannula Oxygen Supplementation in Surgery Patients
Oxygen Administration During Deep Sedation
Primary: Number of Participants With Oxygen Saturations Below 92% — 3; 12 Participants
N/A N=139 Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction
Obstructive Sleep Apnea, Obesity
Primary: Time Taken From Initiation of Induction to the First Airway Intervention — 5; 10 minutes