N/A N=183 Management of Myelomeningocele Study (MOMS)
Meningomyelocele · Spinal Dysraphism
Primary: Infant Death or Need for Ventricular Shunt by 1 Year of Life — 66; 90 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=3 Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot Study
Spina Bifida · Myelomeningocele · Neural Tube Defects
Primary: Maternal Adverse Events — 2 participants
N/A N=46 Neurologic Injuries in Adults With Urea Cycle Disorders
Brain Diseases, Metabolic, Inborn · Urea Cycle Disorder · Ornithine Transcarbamylase Deficiency
Primary: Concentration of Glutamine and Myoinositol by MRS — 4.97; 3.66; 3.78; 4.50 mM — p=0.003
Phase 2 N=5 Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1
Neurofibromatosis 1
Primary: Change From Baseline in Motor Function Measured by Physical and Neurological Examination for Subtle Signs (PANESS) — 0; 3 score on a scale
Early Phase 1 N=10 NAC +taVNS in IDM Who Are Poor Oral Feeders
Infant of Diabetic Mother · Oxidative Stress · Vagus Nerve Stimulation
Primary: Daily Oral Feeding Volumes : Difference in Mean Increase — 2.1 ml/kg/day po daily change — p=0.009
N/A N=89 Neurobiology and Treatment of Reading Disability in NF-1
Neurofibromatosis Type 1 · Reading Disabilities
Primary: Change From Baseline in WJ-III Basic Reading Normative Update (Woodcock Johnson Psychoeducational Battery - 3rd Edition; WJ-III NU) Standard Score at 15 Hours — 13.50…
Phase 2 N=9 Medical Treatment of "High-Risk" Neurofibromas
Neurofibromatosis 1
Primary: Improvement of Symptoms and Pain — 9 Participants
N/A N=4,488 National Prevalence and Impact of Noninvasive Prenatal Testing
Aneuploidy
Primary: Number of Patient Undergoing IDTFK Before (Control) and After (Test) NIPT Testing Came to Market — 1414; 3074 Participants
Phase 3 N=4 Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies
Osteoarthritis · Cancer Pain · Recurrent Low Back Pain
Primary: Occipital-frontal Head Circumference During 0 to Less Than or Equal to (<=) 2 Months of Participant's Age — 38.7; 38.7 cm