Phase 4 N=74 Continuous Glucose Sensor Profiles in Non-Diabetic Subjects
Healthy Subjects Without Type 1 Diabetes
Primary: Overall Mean Sensor Glucose by Age Group — 98; 103; 97; 96 mg/dL — p=0.009
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=49 Normal Breathing and Swallowing in Healthy Volunteers
Healthy
Primary: Reflexive Cough Testing (With Urge-to-Cough) — 3; 5 units on a scale
N/A N=120 Evaluation of Physiological Variables and Detection of Blood Loss in Healthy Adults With Different Subject Positioning by the CM-1500
Fluid Loss · Blood Loss
Primary: Impact of Subject Positioning on Percent Change of Heart Rate (HR) After Minor Blood Loss (e.g., 500mL) — 10.7; 14.7 percent change
N/A N=27 Novel Non-Invasive Monitoring Parameter in Healthy Volunteers
No Conditions · Focus is Respiratory Rate
Primary: The Covidien Nellcor Respiration Rate Software Shall Determine Respiration Rate Measured as Mean and Standard Deviation With Accuracy That is Non-inferior to Predicate…
N/A N=13 Clinical Trial Testing the BioSerenity Pulse Oximeter (EOXY) Efficacy, Performance and Safety in Healthy Volunteer
Healthy
Primary: Percentage SPO2 Accuracy Root-Mean Square (ARMS) at Forehead Position — 3.91; 3.08; 3.36; 2.85 percentage of ARMS (accuracy)
Phase 2 N=25 Positron-Emission Tomography With Vesicular Monoamine Transporter Ligand ([18F]-DTBZ) In Healthy Elderly And Young Subjects
Healthy
Primary: Age-Dependent Change in Striatal 18F-DTBZ Uptake of Healthy Subjects. — 0.05 SUVR
N/A N=40 Clinical Validation Study for Noninvasive Cardiopulmonary Management Device
Cardiopulmonary Disease
Primary: Correlation Coefficient for Accuracy of Test Device vs Reference Device — 0.99; 0.95 Correlation Coefficient
N/A N=200 Urinalysis Results in Healthy Individuals
Asymptomatic Bacteriuria · Asymptomatic Pyuria
Primary: False Positive Urine — 6; 40 Participants
N/A N=30 Respiration Rate V2.0 in Healthy Volunteers
Focus of the Study is Measuring Respiratory Rate
Primary: Mean Error (ME) +/- 1 Breath Per Minute, RR Sensor — -0.05 BrPM
N/A N=30 Effects of Body Mass Index on the Hyperemic Response to Regadenoson
Obesity · Endothelial Dysfunction · Decreased Vascular Flow
Primary: Myocardial Perfusion Reserve Measured by Quantitative Perfusion MRI (Ratio of Myocardial Blood Flow During Stress Over Myocardial Blood Flow at Rest) — 2.25; 2.44 ratio…
N/A N=51 Normative Database for Pattern Electroretinogram (PERG) and Flash Electroretinogram (FERG)
Glaucoma
Primary: Flash Electroretinogram (FERG) Module Using Diopsys NOVA (Neuro Optic Vision Assessment) Amplitude — -1.68 micro volts
N/A N=77 Clinical Evaluation of the CM-1500 During Apheresis Blood Donation
Fluid Loss
Primary: Characterize Changes in the Relative Index During an Apheresis Procedure — 94.9; 99.3 Relative Index
N/A N=12 In Vivo Pulse Oximeter Validation Study
Hypoxia
Primary: Measure of Accuracy (ARMS [%]) — 2.95 Percentage
N/A N=12 Uroflow Measurements in Healthy Volunteers
Healthy
Primary: Voided Volume — 306 mL
N/A N=29 Desaturation Validation of INVSENSOR00012
Healthy
Primary: Oxygen Saturation (SpO2) Accuracy of Sensor — 1.99 % of oxygen saturated hemoglobin
Phase 4 N=16 Safety, Tolerability, and Pharmacokinetic of Single Dose of Pitavastatin 4 mg in Severe Renal Patients Versus Healthy Adult Volunteers
Severe Renal Impairment
Primary: Area Under the Curve From 0 to Tau (AUC 0-t (ng*h/mL)) — 175; 145 nanogram hour per milliliter (ng•h/mL)
Phase 2 N=48 An Electrophysiological Study Of E2014 In Healthy Adult Male Japanese And Caucasian Subjects
Spasmodic Torticollis
Primary: Maximum Rates of Extensor Digitorum Brevis (EDB) Muscle M-Wave Amplitude Reduction From Baseline — 9.02; 48.53; 70.95; 81.62 Percentage of Reduction
N/A N=20 Wearable Dark-adaptometer in Normal Adult Healthy Volunteers
Photoreceptor Sensitivity Thresholds
Primary: Time to Rod-cone Break (RCB) — 11.34; 9.98 Minutes
Phase 1 N=62 Phase 1 Study of ELX-02 in Healthy Adult Subjects
Genetic Disease · Nonsense Mutation
Primary: Pharmacokinetic Parameters - Plasma AUC0-24 — 1105.126; 3125.484; 11018.22; 28235.823 ng*h/mL
N/A N=70 Pivot Breath Sensor Performance Study
Smoking Cessation · Smoking, Tobacco
Primary: User Performance of Pivot Breath Sensor — 68; 2; 70; 0 Participants
Phase 1 N=20 BI 409306 Cardiac Safety Trial in Healthy Volunteers
Healthy
Primary: Slope of the Placebo-corrected Change From Baseline of Heart Rate at Rest and Plasma Concentration Between 0 to 10 Hours — 0.80; 5.46 beats/min
N/A N=351 Evaluation of Physiological Variables and Detection of Blood Loss Using the Zynex Fluid Monitoring System, Model CM-1600
Fluid Loss
Primary: Change in the Relative Index (RI) After Minor Blood Loss (e.g., 500mL) — 2.9 Percent change in RI
N/A N=21 Desaturation Validation of INVSENSOR00031
Healthy
Primary: Oxygen Saturation (SpO2) Accuracy of Sensor by Arms Calculation During Non-motion — 1.33 % of oxygen saturated hemoglobin
N/A N=26 Desaturation Validation of INVSENSOR00006
Healthy
Primary: Oxygen Saturation (SpO2) Accuracy of Sensor — 1.16 % of oxygen saturated hemoglobin
N/A N=20 EXPLORER PET/CT: Evaluation of Healthy Individuals From Racial/Ethnic Minority Populations
Healthy Volunteers From Racial/Ethnic Minority Populations
Primary: Standardized Uptake Value (SUV) in gm/ml Reported as Mean and Standard Deviation — 7.293; 5.157; 4.429; 2.357 gm/ml
Phase 1 N=12 A Study to Understand What the Body Does to the Study Medicine Called PF-07220060 When Taken by Healthy Adults
Healthy Participants
Primary: Percentage of Total Radiocarbon (14C) Excreted in Urine — 11.9; 20.7 Percentage of 14C in urine
N/A N=16 Desaturation Validation of INVSENSOR00009
Healthy
Primary: Trending Regional Oxygen Saturation Accuracy of the INVSENSOR00009 Relative to the Control Sensor by Arms Calculation — 1.3 % tissue oxygen saturation
N/A N=85 Comparison of Non-Invasive Blood Pressure Methods
Blood Pressure
Primary: Validate Non-invasive Blood Pressure Measurement Accuracy for the Vital Detect Blood Pressure Monitor. — 4.40; 4.40; 3.26; 3.26 mmHg
N/A N=16 Active and Passive Music Therapy Interventions
Autonomic Nervous System Imbalance · Hypothalamic Pituitary Adrenal Axis Suppression
Primary: Change From Baseline to Post Intervention High Frequency (HF) and Low Frequency Divided by High Frequency (LF/HF) Power Amplitude — 0.1796; 0.1507; -0.3872; 0.3731…
Early Phase 1 N=5 [18F]F-AraG/Total Body PET Imaging and Healthy Subjects and Lung Cancer Patients
Lung Cancer, Nonsmall Cell
Primary: Data on Whole-body Pharmacokinetics of [18F]F-AraG Physiologic Uptake in Various Healthy Tissues — 0.31; 4.36; 0.04; 32.88 SUV