Phase 4 N=20 Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)
Obsessive Compulsive Disorder
Primary: Y-BOCS Scores at 1st and Last Visit — 27.45; 20.45 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=120 Digital Health Interventions for Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Primary: Difference in OCD Symptom Severity at the End of Week 12 — 25.12; 23.77; 18.68; 20.49 score on a scale — p=0.0871
N/A N=34 Stepped Care for Treating Obsessive-Compulsive Disorder
Obsessive-compulsive Disorder
Primary: Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Total Score — 26.00; 24.47; 14.25; 15.16 units on a scale
Phase 3 N=124 Treatment of Obsessive Compulsive Disorder in Children
Obsessive-Compulsive Disorder
Primary: Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS) — 0.69; 0.34; 0.30 Proportion of Participants with RESPONSE
Phase 2 N=10 Ketamine Infusion for Obsessive-Compulsive Disorder
Obsessive-compulsive Disorder
Primary: OCD Severity — -2.7 units on a scale
Phase 2 N=9 Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)
Obsessive Compulsive Disorder
Primary: Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale — 2 participants
N/A N=100 Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Score on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) — 26.1; 27.2; 25.9; 22.6 units on a scale
Phase 3 N=20 Tolcapone in Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Yale Brown Obsessive Compulsive Scale (Y-BOCS) — -4.24; -1.10 mean change in YBOCS score
N/A N=20 The Use of Magnetic Brain Stimulation to Treat Obsessive Compulsive Disorder, a Pilot Study
Obsessive-Compulsive Disorder
Primary: Change in Obsessive and Compulsive Symptom Severity (Yale-Brown Obsessive Compulsive Scale) — -39.4 Percent change
Phase 2 N=15 Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Primary: Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale. — 0; 5 participants
Phase 4 N=62 Effects of Ondansetron in Obsessive-compulsive and Tic Disorders
Obsessive-Compulsive Disorder · Tic Disorders · Tourette Syndrome
Primary: Change in Brain Activation - Insula Cortex — -0.071; -0.0094 Parameter estimate of BOLD Signal Change
Phase 2 N=38 Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder
Obsessive-compulsive Disorder · Ocd
Primary: Partial Responders by Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) — 5; 2 participants — p=.24
Phase 2 N=34 Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Yale Brown Obsessive Compulsive Scale — 19.14; 21.24 Scores on a scale — p=<0.05
Phase 2 N=27 Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Primary: Clinical Improvement (Yale-Brown Obsessive Compulsive Scale/Y-BOCS) — 36; 9 percentage of participants — p=<0.05
N/A N=55 Overlapping Neural Circuits in Pediatric OCD
Obsessive Compulsive Disorder
Primary: Brain Activation Associated With the Resolution of Cognitive Conflict — .7; .59 Arbitrary units — p=0.0585
Phase 2 N=31 Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Primary: Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS; Scahill et al., 1997). The CY-BOCS is a 10-item Semi-structured Measure of Obsession and Compulsion Severity…
N/A N=7 Rapid Non-Invasive Brain Stimulation for OCD (oTMS)
OCD
Primary: Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale. — 4 Participants
N/A N=66 Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
OCD · Decision-Making · tDCS
Primary: Strength of Behaving Model-based (Goal-directed) — 0.09; 0.07; -0.08; 0.06 units on a scale
N/A N=43 Dealing With Intrusive Thoughts in OCD - a Comparison of Detached Mindfulness and Cognitive Restructuring
Obsessive-Compulsive Disorder
Primary: Y-BOCS Change Score (Pre to Post Assessment) — 5.11; 5.09; 0.25 units on a scale
N/A N=26 Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
Obsessive Compulsive Disorder
Primary: Obsessive Compulsive Symptoms as Measured by Yale-Brown Obsessive Compulsive Scale (Y-BOCS) — 23.9; 23.1; 23.23; 20.6 score on a scale
Phase 2 N=14 Marinol in Trichotillomania or Obsessive Compulsive Disorder
Trichotillomania · Obsessive Compulsive Disorder
Primary: Massachusetts General Hospital Hairpulling Scale (MGH-HPS) Total Score — 8.71 units on a scale
N/A N=12 Transcranial Direct Current Stimulation Augmented Exposure and Response Prevention for Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Yale-Brown Obsessive Compulsive Scale (Y-BOCS): Total Score — 15.5; 16.33 units on a scale
N/A N=26 Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder
Primary: Change in Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) — 24.67; 18.29; 18.46 units on a scale
Phase 2 N=14 Pilot Study to Evaluate Escitalopram in Obsessive-compulsive Disorder
OCD
Primary: Yale Brown Obsessive Compulsive Scale — 24.79; 12.71; 16.00; 15.36 units on a scale — p=0.0002
Phase 2 N=14 Effects of Marijuana on Symptoms of OCD
Obsessive-Compulsive Disorder
Primary: Yale-Brown Obsessive-Compulsive Challenge Scale (YBOC-CS) — 17.45; 17.00; 17.09; 13.36 score on a scale — p=.577
Phase 2 N=12 Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Number of Patients Who Met and Exceeded Response Criteria of Yale-Brown Obsessive-Compulsive Scale. — 4 Participants
Phase 3 N=248 Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: Change From Baseline in the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Total Score — -5.91; -4.91 Scores on a scale — p=0.2202
Phase 3 N=142 D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
Obsessive-compulsive Disorder
Primary: Children's Yale-Brown Obsessive-Compulsive Scale. — 13.53; 13.98 units on a scale
N/A N=33 Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
Obsessive Compulsive Disorder · Trichotillomania
Primary: Composite Score of Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and National Institute of Mental Health (NIMH) — -.38; .46; -.89; -.52 z scores — p== 0.56
Phase 2 N=11 N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: OCD Severity at 12 Weeks — 21.4; 21.3 points on a scale