30 closest matches · ranked by relevance
Dry Eye Disease
Primary: Change From Baseline in Total Corneal Fluorescein Staining (tCFS) at Day 60 — -2.04; -1.65; -2.15; -1.54 tCFS score on a scale of 0 - 20
Dry Eye
Primary: Symptom Assessment in Dry Eye (SANDE) Questionnaire — -25.66; -25.14; -29.95; -24.81 units on a scale
Environmental Exposure
Primary: Tear Evaporation Rate — 39.0; 44.8; 30.6; 26.7 Watt/meter^2
Dry Eye Disease
Primary: Mean Change From Baseline in Average Lissamine Green Staining in the Study Eye — -0.65 score on a scale
Keratoconjunctivitis Sicca · Dry Eye Disease
Primary: Conjunctival Staining — -1.9; -1.8; -1.2 score on a scale
Dry Eye
Primary: Change in Ocular Surface Disease Index (OSDI) — 25.8; 25.8; 24.8; 12.8 score on a scale
Dry Eye
Primary: Symptom Assessment in Dry Eye (SANDE) Questionnaire — 58.95; 57.21; -18.80; -16.60 units on a scale
Keratoconjunctivitis Sicca
Primary: Ocular Surface Disease Index (OSDI) Total Score at Baseline — 40.3 Scores on a Scale
Keratoconjunctivitis Sicca
Primary: Tear Production — 16.6; 9.2 Percentage of eyes
Dry Eye
Primary: Tear Lipid Layer Thickness — 0.72; -7.58; 2.06; 1.41 nm
Dry Eye Disease
Primary: Change From Baseline in Impact of Dry Eye on Everyday Life - Symptom Bother (IDEEL-SB) Questionnaire Score at Day 30 — -16.95 score on a scale — p=<.0001
Dry Eye
Primary: Change From Baseline in Drop Discomfort Post Dose Instillation on Day 1 — 7.9; 3.5 mm — p=0.1491
Dry Eye Disease
Primary: Mean Change From Baseline in Lacrimation Assessed by Schirmer's Test — 3.02; 2.15; 2.35; 1.35 mm
Dry Eye Syndromes
Primary: Number of Participants Very Satisfied or Satisfied With OPTIVE PLUS® — 356; 746 Participants
Dry Eye Syndromes · Keratoconjunctivitis Sicca
Primary: Change From Baseline in Global Ocular Staining Score at Day 35 — 5.4; 5.9; -1.8; -1.8 Number on a scale (score)
Dry Eye Disease
Primary: Change From Baseline in Patient-Reported Eye Dryness Score to Day 84 — 69.0; 68.3; -30.7; -37.9 units on a scale — p==0.0007
Dry Eye Disease
Primary: Treatment-Emergent Serious Adverse Events (TE-SAEs) of Visual Acuity Decrease — 0; 0 Participants
Dry Eye Syndrome
Primary: Efficacy of ADX-102 on the Ora Calibra® Discomfort & 4-Symptom Questionnaire for Dryness. — -0.7; -0.5; -0.4 units on a scale
Dry Eye
Primary: Photographic Assessment of Bulbar Conjunctival Hyperemia Change in Score From Baseline (CFB) at 15 Days (Evaluated Via Central Reading Center). — -0.51; -0.43; -0.21…
Dry Eye Disease
Primary: Least Squares Mean Percentage Change From Baseline in Goblet Cell Density at Day 90 for 0.003% AR-15512 — 94.61 percent change — p=0.1765
Dry Eye
Primary: Total Corneal Fluorescein Staining — 4.09; 5.05 units on a scale
Dry Eye Disease
Primary: Change From Baseline in Total Corneal Fluorescein Staining at Day 29 — -2.9; -2.2 score on a scale
Dry Eye Disease
Primary: University of North Carolina Dry Eye Management Scale (UNC DEMS) Responder Analysis — 65.4; 90.0; 66.0; 71.4 percentage of responders — p=0.0040
Keratoconjunctivitis Sicca
Primary: Number of Subjects Who Achieved Complete Clearing of Corneal Staining (i.e., Total Corneal FS Score = 0) at Week 24 — 15; 13; 21; 61 participants
Dry Eye
Primary: Change From Baseline in Tear Break up Time(TBUT ) at Day 84 — 1.45; 1.23 seconds
Aqueous Deficient Dry Eye · Meibomium Gland Dysfunction
Primary: Visual Quality — 0.3; 0.32; 0.19; 0.3 microns
Dry Eye Disease
Primary: Number of Subjects With At Least One (1) Treatment Emergent Adverse Event — 0; 16; 15; 5 count of participants
Dry Eye Syndromes
Primary: Efficacy of ADX-102 on Ocular Discomfort Using the Ora Calibra® Ocular Discomfort Scale. — -0.81; -0.75; -0.82 units on a scale
Ocular Surface Disease
Primary: Ocular Surface Disease Index (OSDI) Score Change (1 Month Post Treatment Initiation) — -3.83 score on a scale
Keratoconjunctivitis Sicca
Primary: Diagnostic Test Data for Disease Using Tear Osmolarity Threshold > 308 mOsm/L — 177; 14; 47; 61 participants