N/A N=162 Tumor: Breast Ratio Study
Breast Cancer · LCIS · DCIS
Primary: Quality of Life as Measured by the Breast Q — 61.9; 57.6; 74.2; 64.2 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=47 Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction
Breast Cancer
Primary: Quality of Recovery Score — 165; 169 score on a scale
N/A N=36 Force Modulating Tissue Bridges for Closure of Vertical Scars in Breast Reduction
Surgical Incision
Primary: Patient and Observer Scar Assessment Scale (POSAS)- Patient Scores 12M — 1.09; 1.22; 1.3; 1.87 score on a scale
Phase 4 N=60 PEMF and PEC Blocks in Mastectomy Reconstruction Patients
Breast Cancer Female
Primary: Score on Visual Analog Scale (VAS) - 1 Hour Post-intervention — 6.64; 6.67; 4.62; 6.93 score on a scale
Phase 4 N=101 Coated VICRYL* Plus Suture Compared to Chinese Silk in Scheduled Breast Cancer Surgery
Breast Cancer
Primary: Mean Score on Cosmetic Outcome Visual Analog Scale (VAS) — 45.4; 67.2 score on scale
Phase 2 N=270 Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer
Breast Cancer
Primary: Local Recurrence — 3.1 percentage of participants
N/A N=68 Seroma Formation After Modified Radical Mastectomy With Flap Fixation Technique in Breast Cancer Patients
Breast-cancer
Primary: Seroma Formation — 54.27; 59.56; 102.21; 117.94 ml — p=<0.005
Phase 3 N=2,108 Regional Anesthesia and Breast Cancer Recurrence
Breast Neoplasms
Primary: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery — 111; 102 participants — p=0.84
N/A N=94 The Use of a High-frequency Ultrasonic Knife in Breast Cancer Surgery
Breast Cancer
Primary: Drainage Volume — 182.6; 525.2 milliliters — p=<0.05
N/A N=1 Prospective Evaluation of a Surgical Solution for Breast Cancer-Associated Lymphedema
Lymphedema · Edema
Primary: Change in Limb Volume — -15; -202 mL
Phase 2 N=60 Feasibility Study of Intraoperative Imaging in Breast Cancer
Breast Cancer
Primary: (Phase A Only) Selection of Dose of LUM015 to be Used in Future Breast Trials — 2.1; 4.7; 4.2 Ratio
Phase 2 N=234 Intraoperative Detection of Residual Cancer in Breast Cancer
Breast Cancer
Primary: Collect Data to Refine and Verify the Tumor Detection Algorithm. — 11.3 Percentage
N/A N=129 Reducing Pain and Disability After Breast Cancer Surgery
Breast Cancer · Chronic Pain
Primary: The Proportion of Individuals Reporting Chronic Postoperative Pain 12 Months Following Breast Cancer Surgery With Lymph Node Dissection. — 5; 4 Participants
N/A N=934 Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases
Breast Cancer
Primary: 5-year Disease-Free Survival — 84.4; 87.8 percentage of participants — p=0.004
Phase 2 N=257 Preoperative Treatment of Breast Cancer With Two Different Sequential Treatment Regimens
Breast Cancer
Primary: Number of Participants With a Pathological Complete Response — 21; 24; 99; 89 participants
N/A N=50 Evaluation of the Cook Biodesign® Nipple Reconstruction Cylinder (NRC)
Breast Cancer · Breast Reconstruction · Nipple Reconstruction
Primary: Percent Nipple Projection at 12 Months Compared to Baseline (1 Week Post-procedure) — 37.3 percentage of projection vs baseline
Phase 4 N=21 Symptom Management After Breast Cancer Surgery
Neuropathic Pain · Postmastectomy Pain
Primary: Change in Pain Intensity on an 11-point Scale From Baseline to 12 Weeks — 4.0 units on a scale
N/A N=32 Cosmetic Result/Toxicity in Post-Mastectomy Immediate Reconstruction Expander+RT
Breast Cancer
Primary: Success Rate — 65.4 percentage of participants
Phase 2 N=61 Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer
Breast Cancer Female
Primary: Measure Ki67 Index in Highly Hormone-dependent Breast Cancers vs. Those That Are Not — 7; 6; 40 Participants
N/A N=13 Upper Extremity Lymphatic Mapping for Breast Cancer Patients
Breast Cancer · Axillary Lymph Node Dissection
Primary: Number and Prevalence of Metastases of Blue Nodes in the ALND Specimen (Nodes Draining the Breast). — 0 participants
Phase 3 N=88 Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery
Breast Cancer
Primary: Proportion of Participants With No Pain Immediately After Surgery
N/A N=40 Regenerative Collagen Scaffold for Breast Volume Restoration After Breast Cancer Excision
Breast-Conserving Surgery
Primary: Volume Restoration — 33 Participants
N/A N=198 One-stage Breast Reconstruction Using Dermal Matrix/Implant Versus Two-stage Expander/Implant Procedure
Breast Cancer
Primary: BreastQ Quality of Life and Satisfaction Questionnaire — 65.32; 67.07 score on a scale — p=0.05
N/A N=20 Comparison of One-port and Two-port Tissue Expanders for Breast Reconstruction
Breast Cancer
Primary: Number of Participants With Successful Replacement of Tissue Expander With Permanent Implant — 8; 12 Participants
Phase 4 N=79 Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
Macromastia
Primary: Continuous Apposition of the Skin Edges Without Wound Dehiscence or Re-closure as Measured by the Upper Limit of 95% Confidence Interval in Proportion of Successes for…
N/A N=79 Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction
Ductal Carcinoma in Situ - Category · Breast Cancer · Prophylactic Mastectomy
Primary: Percentage of Original Preoperative Blood Supply (Perfusion) Post Nipple Sparing Mastectomy — 63.9; 60.8; 29.9; 40.0 percentage of original preop perfusion
Phase 1 N=35 Single Dose Partial Breast Radiotherapy
Breast Cancer
Primary: Maximum Tolerated Dose — 21 Gray (Gy)
N/A N=97 Study of Prone Accelerated Breast And Nodal IMRT
Lymphedema
Primary: Number of Participants With Acute Toxicity > Grade 2 (Skin Toxicity Grade 3 or Above) Occurring Within 60 Days After First Day of Treatment — 4 Participants
N/A N=102 Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
Stage I Breast Cancer · Stage II Breast Cancer
Primary: Proportion of Sentinel Lymph Nodes (SLNs) Flagged by the Two Methods — 0.86; 0.95 proportion of nodes
N/A N=159 A Study to Evaluate the Use of Supine MRI Images in Breast Conserving Surgery
Breast Cancer
Primary: The Mean Distance Between the Image-defined and Palpation-defined Edges of the Tumor. — 7.2 mm