N/A N=148 The Pediatric Intermed: A New Clinical Decision Making Tool
Inflammatory Bowel Disease
Primary: Pediatric INTERMED- Complexity Index — 24; 9.0; 4.0; 4.0 scores on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=33 Systematic Pediatric Assessment of Rome Criteria (SPARC)
Functional Gastrointestinal Disorders
Primary: Resolution of Symptoms From Initial Rome IV Diagnosis at 3 Months Using an Age-appropriate Rome IV Questionnaire. Number of Participants Who no Longer Meet Rome IV…
Phase 1 N=105 Lurasidone Pediatric Pharmacokinetics Study
Schizophrenia · Autism
Primary: Lurasidone Primary Pharmacokinetic Parameters — 78; 140; 300; 115 ng.h/mL
Phase 2 N=11 N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Obsessive-Compulsive Disorder
Primary: OCD Severity at 12 Weeks — 21.4; 21.3 points on a scale
N/A N=39 Early-onset Obesity and Cognitive Impairment in Children With Pseudohypoparathyroidism
Pseudohypoparathyroidism · Albright Hereditary Osteodystrophy
Primary: Intelligence Quotient — 85.9; 104.3; 103.2 units on a scale
Phase 3 N=92 A Short Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder
Autistic Disorder
Primary: Mean Change From Baseline in the Aberrant Behavior Checklist Japanese Version (ABC-J) Irritability Subscale Score — -11.4; -7.5 units on a scale
Phase 3 N=327 Pediatric Schizophrenia Efficacy and Safety Study
Schizophrenia
Primary: Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 6. — 94.5; 94.0; 92.8; -18.6 units on a scale — p=0.0003
N/A N=40 Umbilical Cord Blood Transplant for Congenital Pediatric Disorders
Congenital Pediatric Disorders
Primary: Overall Survival at 100 Days After Umbilical Cord Blood Transplant in Pediatric Patients. — 0.947 probability of overall survival
Phase 2 N=58 Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders
Mood Disorder · Disruptive Behavior Disorders
Primary: Change in Affective Reactivity Index - Youth (ARI-Y) — -2.9; -0.8 score on a scale
N/A N=116 Pediatric Guideline Adherence and Outcomes- Argentina
TBI (Traumatic Brain Injury)
Primary: First 3-day Cumulative Intensive Care Unit (ICU) Traumatic Brain Injury (TBI) Guideline Adherence Rate, Overall — 81.7; 81.0; 83.7; 84.4 mean percentage of guideline…
Phase 2 N=30 D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder
Obsessive-compulsive Disorder
Primary: Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS; Scahill et al., 1997). — 26; 24.1; 17.9; 15.6 units on a scale — p=<0.05
Phase 3 N=61 Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder
Chronic Motor or Vocal Tic Disorder · Tourette's Disorder
Primary: Mean Change of Total Tic Scores in K-YGTSS From Randomization (Baseline, Visit 2) to the Final Visit (Visit 7) — -9.62; -14.97 units on a scale
Phase 3 N=33 Study of Aripiprazole in the Treatment of Pervasive Developmental Disorders
Pervasive Developmental Disorder
Primary: Number of Participants Improved as Measured by the Clinical Global Impression-Global Improvement Scale (Improvement Defined as CGI-I=1 or CGI-I=2) — 11; 3 participants
N/A N=41,054 Pediatric Blood Pressure Clinical Decision Support Tool (PedsBP CDS)
Hypertension
Primary: Blood Pressure Remeasurement — 245; 829; 1813 participants — p=<0.001
N/A N=30 Parent Acceptance and Commitment Therapy (PACT) for Parents of Children With Pediatric Feeding Disorder
Pediatric Feeding Disorder, Chronic · Pediatric Feeding Dysfunction, Acute
Primary: Patient Health Questionnaire-9 (PHQ-9) — 2; 0; 12; 0 Participants
Phase 4 N=577 Evaluation of an Intervention for Improving Community-based Pediatric Attention-Deficit Hyperactivity Disorder (ADHD) Care
ADHD
Primary: Parent-rated ADHD Symptoms — 20.5; 24.1 scores on a scale — p=<.05
Phase 3 N=71 Phase III Study To Compare The Effect of Panzyga Versus Placebo in Patients With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS/PANDAS)
Pediatric Acute-Onset Neuropsychiatric Syndrome
Primary: Percentage Change in CY-BOCS Score From Baseline to Week 9 — 12.1; 31.1 Percentage Change at Week 9 to Baseline — p=0.0718
Phase 3 N=350 Lurasidone Pediatric Bipolar Study
Bipolar I Depression
Primary: Change in the Children's Depression Rating Scale, Revised (CDRS-R) Total Score as Compared to Placebo From Double-Blind Baseline to Week 6 (Day 43) Baseline — 59.2…
N/A N=84 Using Computers to Assist in the Diagnosis and Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder
Primary: Number of Children Diagnosed With ADHD With Structured Diagnostic Assessment — 34; 16 number of kids
Phase 3 N=45 Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism · Asperger's Syndrome · Generalized Anxiety Disorder
Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale
Phase 3 N=48 Intravenous Immunoglobulin for PANDAS
Obsessive-Compulsive Disorder · Children · Anxiety Disorder
Primary: Children's Yale-Brown Obsessive Compulsive Scale Total Score — 20.59; 25.67 units on a scale — p=0.44
Phase 2 N=903 An Open-Label Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Autism Spectrum Disorder (ASD) · Autism · Autistic Disorder
Primary: Number of Confirmed Social Responsiveness Scale (SRS) Responders — 517; 351 participants
Phase 3 N=298 Lamictal as Add-on Treatment for Bipolar I Disorder in Pediatric Patients
Bipolar Disorder
Primary: Time From Randomization to the Occurrence of a Bipolar Event (TOBE) — 50; 155; 120; 163 Days — p=0.0717
N/A N=17 Pediatric Aggression and Violence
Pediatric Aggression and Violence
Primary: Salivary Hormone Correlation With Brief Rating of Aggression by Children and Adolescent (BRACHA) Score — 0.8; 0.4; 0.3; 0.4 ul/dL
Phase 3 N=142 D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD)
Obsessive-compulsive Disorder
Primary: Children's Yale-Brown Obsessive-Compulsive Scale. — 13.53; 13.98 units on a scale
N/A N=4,350 Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
Diagnostic Errors
Primary: Number of Adolescents Diagnosed With Depression Seen in Well Child Visits — 233; 443 Participants — p=<0.0001
Phase 2 N=63 Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria
Tourette Syndrome
Primary: Mean Change From Baseline in Total Tic Score of the Yale Global Tic Severity Scale — -7.17; -7.16 score on a scale — p=0.996
Phase 3 N=63 A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents
Cerebral Palsy, Dyskinetic
Primary: Change From Baseline in the Movement Disorder-Childhood Rating Scale (MD-CRS) Part II Total Score (Movement Disorder Severity, Centrally Read) at Week 15 — -0.4; -1.5…
Phase 2 N=48 Lamotrigine Monotherapy in Pediatric Bipolar Disorder
Bipolar Disorder
Primary: Young Mania Rating Scale (YMRS), — 19.61; 7.06; 5.68 units on a scale
Phase 3 N=86 A Long-term, Extended Treatment Study of Aripiprazole in Pediatric Patients With Autistic Disorder
Autistic Disorder
Primary: Mean Change From Baseline at the Final Assessment in Aberrant Behavior Checklist Japanese Version (ABC-J) Irritability Subscale Score — -3.2 units on a scale