Clinical Trial Search

Primary: Postoperative Facial Swelling (Sum of 3 Linear Distances, mm) — 122.08; 118.55; 116.90; 119.68 Millimeters (mm)

Primary: Number of Patients Needing Rescue Medication — 32; 29 Participants

Primary: Sum of Pain Intensity Difference (SPID) Using the Pain Intensity Visual Analog Scale (VAS) — 268.8; 230.9; 54.8 scores on a scale

Primary: Total Pain Relief From 0 to 6 Hours (TOTPAR[6]) — 6.94; 6.21; 7.00; 14.43 units on a scale

Primary: Area Under the Curve (AUC) of Numeric Rating Scale (NRS) Pain Intensity Scores Through 48 Hours — 178.9; 181.6 units on NRS scale*hr — p=0.8661

Primary: Radiographic Bone Changes — -1.12; -2.60; -1.16; -.158 millimeter

Primary: Sum Pain Intensity Difference Scores — -2.4292; -68.0778; -68.3533; -93.3645 score on a scale

Primary: Onset of Anesthetic — 1.5; 1.5 minutes — p=0.192

Primary: Sum of Pain Intensity Difference From 0 to 24 Hours (SPID24) Based on the 11 Point Numeric Pain Rating Scale — -96.80; -100.69; -74.96 score on a scale — p=0.0258

Primary: Postoperative Pain — 51.4; 56.3; 60.9 score on a scale

Primary: Total Pain Relief at 6 Hours Post Dose (TOTPAR 6) — 2.45; 4.37 units on a scale

Primary: Total Pain Relief Based on Numerical Rating Scale (NRS) Score — 17.7; 12.4; 13.3 Units on a scale — p=<0.0001

Primary: Mean of Pain Intensity Based on the Visual Analogue Scale (VAS) — 37.45; 34.95; 38.84; 17.15 Scores on a Scale

Primary: 24 Hour Postoperative Pain for Patients Seen From 09/2020-06/2021 — 14.75; 16.23 score on a scale — p=0.63

Primary: Area Under the Curve (AUC) of the Pain Scores. — 6843; 8832; 9998; 7290 mm*minutes

Primary: Postoperative Pain, as Measured by Wong-Baker Facial Rating Pain Scale ,After Routine Dental Treatment — 20; 20; 7; 11 Participants

Primary: Occurrence of Pain at Follow-up With Wide Opening, or Pain in the Temple, Jaw Joint or Jaw Muscles. — 26; 32; 54; 53 Participants

Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 10.60; 5.87; 3.35 Units on a scale — p=0.0004

Primary: Summed Pain Intensity Difference Over 0 to 12 Hours (SPID12) After Time 0 — 51.84; 56.33; 19.11 score on a scale*hours — p=<0.0001

Primary: Ranked Endpoints : 1. Sum of Pain Intensity Differences at 6 Hours (SPID0-6h) — 8955.4; 8458.0; 5290.7 score on a scale — p=0.0031

Primary: Pain Reported by Patient — 1.6; 2.9 score on a scale

Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale

Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 16.08; 12.42; 4.63 Score on a scale — p=0.0009

Primary: Pain Intensity Difference (PID) on a 0-100 VAS — 36.5; 37.3; 37.7; 12.3 mm — p=< 0.001

Primary: Overall Summed Pain Intensity Difference (SPID) — 74.5; 82.4; 96.8; 50.5 score on a scale x hours — p=0.123

Primary: Pain as Assessed by a Visual Analogue Scale (VAS) — 4; 2.33 score on a scale

Primary: Analgesic Efficacy, as Measured by the Sum of Pain Intensity Differences (SPID) Scale — 14.80; 0.40 Units on a scale — p=<0.0001

Primary: Time Weighted Sum of Pain Intensity Difference (PID) Over 10 Hours (SPID 0-10) — 5.745; 30.986 units on a scale — p=<0.001

Primary: Change From Baseline in Cumulative Pain on the Visual Analogue Scale (VAS) at Postoperative Week 1 — 3.27; 4.35 score on a scale

Primary: Opioid Prescribing at the Extraction Encounter — 443; 643; 418 Participants — p=.08