N/A N=20 Cervix Monitor for Elasticity and Length Measurements
Preterm Birth
Primary: Cervix Elasticity — 54; 19.7 kPa
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=122 Prevention of Preterm Birth With a Pessary in Singleton Gestations
Preterm Birth · Short Cervix
Primary: Number of Subjects Experiencing Preterm Birth — 26; 23 Participants
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
Phase 2 N=21 Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.
Pregnancy Complications
Primary: Number of Participants With Achievement of 34 Weeks Gestation — 0; 0 Participants
Phase 2 N=482 Reducing Preterm Births in Underserved Pregnant Women
Preterm Birth · Low Birth Weight <2500 Grams · Verylow Birthweight <1500 Grams
Primary: Birthweight — 40; 26 participants
N/A N=175 Preemie Prep For Parents (P3): Home Antenatal Prematurity Education
Premature Birth · Decision Making · Prenatal Care
Primary: Parent Prematurity Knowledge Questionnaire — 30.3; 22.8; 29.3; 25.6 score on a scale
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
N/A N=144 The Use of Progesterone to Reduce Preterm Birth
Preterm Birth
Primary: Weeks Gestation at Birth Among Patients Receiving the Active Drug. — 31.9; 30.2 weeks
N/A N=385 Prevention of Preterm Birth Using Cervical Pessary in Pregnant Women With Short Cervix
Preterm Birth
Primary: Spontaneous Delivery Before 34 Completed Weeks — 51; 12 Participants
Phase 2 N=29 The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Obstetric Labour, Premature
Primary: Number of Participants With Vital Sign Values of Potential Clinical Concern — 2; 4; 0; 3 Participants
Phase 2 N=271 Efficacy Study of a Cervical Pessary Containing Progesterone for the Prevention of Preterm Delivery
Preterm Birth
Primary: Number of Participants Not Giving Birth Before Week 32 and Week 34 of Gestation — 73; 71; 67; 66 Participants
Phase 3 N=152 Progesterone (17P, Makena®) for Prolongation of Pregnancy in Women With Preterm Rupture of the Membranes (PROM)
Preterm Delivery
Primary: Gestational Age at Delivery — 29.2; 29.5 weeks.
N/A N=301 Tocolysis for Preterm Labor
Preterm Labor
Primary: The Primary Outcome Measure of This Research is to Compare the Efficacy of the Three Clinically Used Tocolytic Agents in a Prospective Study That Will Allow Direct…
Phase 3 N=321 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Preterm Birth
Primary: Newborn Respiratory Distress Syndrome (RDS) — 44; 18 Twins
Phase 3 N=465 PREGNANT Short Cervix Trial
Preterm Delivery · Short Cervix · Short Uterine Cervical Length
Primary: Number of Participants With Birth <=32 6/7 Weeks Gestation. — 36; 21 participants — p=0.020
N/A N=30 Improving the Clinical Encounter to Enhance Delivery of an Individualized Prematurity Prevention Plan
Preterm Birth
Primary: Feasibility as Measured by Number of Recruited Eligible Patients Enrolled — 30 Participants
Phase 4 N=140 Feasibility of Vaginal Progesterone to Reduce HIV-Associated Preterm Birth
PreTerm Birth
Primary: Adequate Adherence to Study Product — 62; 63 Participants
Phase 3 N=1,311 A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix
Short Cervical Length
Primary: Number of Participants With Delivery or Fetal Loss of Either Twin Prior to 35 Weeks Gestation — 84; 84; 86 Participants
N/A N=11,976 Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)
Premature Birth
Primary: Incidence of Preterm Birth — 668; 754 Participants — p=0.012
N/A N=236 Tennessee Connections for Better Birth Outcomes
Preterm Birth
Primary: Infant Gestational Age — 38.14; 38.14 weeks — p=.64
N/A N=174 Comparing IM vs. Vaginal Progesterone for Pre-term Birth
Infant, Premature · Premature Birth
Primary: Preterm Birth — 29; 30 Participants
Phase 3 N=2,831 Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Pregnancy · Respiratory Distress Syndrome · Pregnancy Outcomes
Primary: Neonatal Composite Outcome — 165; 202; 145; 184 Participants — p=0.02
N/A N=175 PREPP: Preventing Postpartum Depression
Postpartum Depression (PPD)
Primary: Score on the Edinburgh Postnatal Depression Scale (EPDS) — 5.04; 4.36; 4.43; 4.04 score on a scale
Phase 3 N=1,708 Confirmatory Study of 17P vs Vehicle for Prevention of Preterm Birth in Women w/ Previous Spontaneous Preterm Delivery
Preterm Birth
Primary: Preterm Birth <35 Weeks Gestation — 66; 122 Participants
Phase 4 N=108 Pitocin or Oral Misoprostol for PROM IOL
PROM
Primary: Time From Induction of Labor (IOL) to Delivery — 18.1; 14.9 Hours
N/A N=6 Heart Rate Variability and Prematurity
Premature Birth · Maternal Distress - Delivered · Stress
Primary: Feasibility: Acceptance (Ratio) — 33.3 percentage of <participants>
Phase 4 N=205 Vaginal Versus Intramuscular Progesterone for the Prevention of Recurrent Preterm Birth
Premature Birth
Primary: Preterm Birth <37 Weeks — 29; 36 Participants
Phase 3 N=36 Oral Progesterone for Prevention of Preterm Birth
Preterm Birth
Primary: Rate of Recurrent Preterm Birth — 5; 8 participants
N/A N=38 Feeding and Wellness Among Late Preterm Infants
Late Preterm Infant
Primary: Phone Call Completion Rate — 194; 102; 59; 52 calls
N/A N=20 A Novel Parent Education Program for Early Intervention
Preterm Infant · Full-term Infant
Primary: Alberta Infant Motor Scale - Change in Total Percentile Score — 10; 0 change in percentile rank — p=0.016