N/A N=15 Effects of Different Support Surfaces on the Properties Skin After Loading
Pressure Ulcers
Primary: Transepidermal Water Loss (TEWL) in g/m2/h on Sacrum, at Baseline — 7.8; 7.7; 7.1 g/m2/h
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=16 Novel Offloading for Diabetic Foot Ulcers With PulseFlow: A Prospective Study
Diabetic Foot Ulcer · Offloading
Primary: Lower Extremity Perfusion Change From Baseline to 4 Weeks — 167; 75 percentage of baseline perfusion
N/A N=21 Evaluation of Heel Offloading Devices for Reducing Heel Contact Pressures in Healthy Volunteers
Heel Pressure Ulceration Prevention Strategies
Primary: Average Contact Force Exerted on the Heel — 60.25; 39.74; 5.57; 29.34 mmHg — p=<0.00005
N/A N=20 Pressure Alternating Shoes
Foot Ulcer, Diabetic
Primary: Maximum Average Pressure at Baseline With Pressure Alternating Shoes, Right Foot (Before Any Cells Were Offloaded) — 118.5; 113.7; 96.6; 54.9 kPa
N/A N=102 Comparison of the Effectiveness of Two Medical Compression Bandage Application Techniques by Measuring Interface Pressures Depending on Whether or Not the Heel is Included in Patients With Open Venous Ulcers
Venous Ulcer
Primary: Interface Pressure at V3 — 28.4; 30.1 mmHg
N/A N=27 Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer
Diabetic Foot Ulcer · Diabetic Foot
Primary: Plantar Foot Temperature Changes in Regions-of-interest in Response to Walking — 0.758; 0.272 Absolute change in temperature degrees
N/A N=144 Self-Management to Prevent Ulcers in Veterans With SCI (Spinal Cord Injury)
Pressure Ulcers · Spinal Cord Injuries
Primary: Percent of Possible Self-Reported Skin Care Behaviors — 73.8; 74.1; 83.5; 79.5 % of Possible Self-Reported Behaviors
N/A N=80 Treatment of Pressure Ulcers Using Biological Skin Substitutes
Pressure Sore
Primary: Percent Change in Wound Area — -78.5; -65.1 percentage change
N/A N=80 Polyurethane Foam on the Heel for Prevention in Children
Flat Foot · Pressure Ulcer
Primary: Heel Pressure Sores (Numbers of Participants With Heel Pressure Sores) — 17; 21 Participants
Phase 2 N=30 Micro-mobile Foot Compression and Diabetic Foot
Diabetes · PAD · Lower Extremity Edema
Primary: Change in Balance From Baseline to 4 Weeks — 0.94; 0.76 cm
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
Phase 2 N=140 Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
Venous Hypertension Ulcers · Venous Stasis Ulcer · Venous Ulcer
Primary: Number of Participants With Ulcer Recurrence — 6; 3; 11; 5 participants — p=0.091
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
N/A N=475 Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention
Pressure Ulcer
Primary: Number of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion) — 6; 22 Pressure ulcer
N/A N=1,633 Silicone Adhesive Multilayer Foam Dressings to Prevent Pressure Ulcer
Pressure Ulcer
Primary: Number of Participants Who Developed a New Pressure Ulcer Category 2 or Worse on Sacrum, Heels or Greater Trochanter — 43; 34 Participants — p=0.04
N/A N=359 Polyurethane Foam on the Sacrum for Prevention
Hip Fracture · Pressure Ulcer
Primary: Number of Participants With Pressure Sores — 8; 28 Participants
N/A N=381 Therapeutic Stockings to Prevent Foot Ulcers
Diabetes
Primary: Number of Participants Who Developed Foot Ulcer During Study Time Frame — 76; 82 Participants
N/A N=258 Wheeled Mobility for Preventing Pressure Ulcers
Mobility Limitation
Primary: Incidence of a Sitting-induced Pressure Ulcer — 19; 15; 75; 69 Participants — p=0.77
N/A N=10 P400 for Stage II-IV Pressure Ulcers in Home and Extended Care
Pressure Ulcers
Primary: Change From Baseline in Ulcer Surface Area at Week 12 — -7.96 cm^2
Phase 2 N=175 Preventing Diabetic Foot Ulcers Through Cleaner Feet
Diabetic Foot Ulcer
Primary: Time to New Foot Complication Among All Randomized Participants — 12; 14 Participants
N/A N=20 Validation of a Novel Foot Offloading Device
Plantar Fasciitis, Chronic · Heel Pain Syndrome · Fat Pad Syndrome
Primary: Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Pittsburgh Foot Survey. — 2.930 Score on a scale — p=0.0796
Phase 3 N=251 Low Dose Aspirin for Venous Leg Ulcers
Venous Leg Ulcer
Primary: Time to Complete Healing of Reference Ulcer — 77; 69 days — p=0.246
Phase 4 N=65 Pressure Ulcer Healing With Microcyn
Pressure Ulcer · Spinal Cord Injuries
Primary: Pressure Ulcer Size (Length x Width x Depth, cm^3) at Baseline — 10.13; 21.00 cm^3
Phase 4 N=29 A Multi-centre Evaluation of the Performance of Window Dressings on Subjects With High Risk Pressure Ulceration
Pressure Ulcer
Primary: Erythema ( No/Yes) — 5; 24; 16; 13 participants
N/A N=12 A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.
Diabetic Foot Ulcer · Peripheral Arterial Disease · Wound; Foot
Primary: Transcutaneous Oxygen Pressure (TcPO2) — 50.96 mmHg
N/A N=28 Ankle-foot Orthoses for Peripheral Artery Disease
Peripheral Artery Disease
Primary: Change in WIQ Distance Subscore — 22.7; -7.2 Scale units
N/A N=3 Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses
Diabetes Mellitus · Peripheral Neuropathy · Orthotic Device
Primary: Peak Plantar Pressure — 75.3; 14.2; 14.5; 22.8 Newtons per squared centimeters
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
N/A N=272 Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Amputation · Amputation; Postoperative, Sequelae · Wound Dehiscence
Primary: Overall Rate of Wound Complications — 26; 31 Participants
N/A N=50 Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings
Pressure Incidence Prevention
Primary: User Friendliness of Both Sacrum and Heel (Left & Right) Dressings: Comfort, Conformability, Acceptability, the Handling at Application and Ease of Inspection of the…