N/A N=6 Safety of Spine Radiofrequency Procedures
Radiofrequency Ablation in Patients With Spinal Hardware
Primary: Number of Procedures in Which Temperature of Screws Increased — 4; 2 procedures
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=298 Radiofrequency (RF) Ablation Prospective Outcomes Study
Pain, Chronic
Primary: Patient Global Impression of Change (PGIC) — 66; 78; 54; 13 Participants
N/A N=51 Spinery® A Novel Radio-Frequency Tumor Ablation Device for Spine Metastatic Tumors
Vertebral Metastasis
Primary: Change From Baseline in Worst Pain and Quality of Life Scores at 3 Months Using the Brief Pain Inventory (BPI) and EQ-5D-5L Questionnaires — 3.4; 65.2 points on a…
Phase 3 N=165 SMART-SF Radiofrequency Ablation Safety Study
Atrial Fibrillation
Primary: Percentage of Participants With Early Onset Primary Adverse Events — 2.6 Percentage of participants
N/A N=25 Use of Radiofrequency Ablation for RGB Salvage
Obesity
Primary: Excess Body Weight Loss After RFA Treatment — 28.36 percentage of EBWL
N/A N=225 SMART Clinical Study: Surgical Multi-center Assessment of RF Ablation for the Treatment of Vertebrogenic Back Pain
Low Back Pain
Primary: Change in ODI From Baseline to 3 Months Post-treatment — -20.5; -15.2 units on a scale — p=0.019
N/A N=51 Radiofrequency Ablation in Treating Patients With Liver Cancer and Cirrhosis
Liver Cancer
Primary: Proportion of Participants With Successful Control of Disease at 18 Months — .18 proportion of participants
N/A N=137 Laparoscopic Radiofrequency Ablation (RFA) of Symptomatic Uterine Fibroids
Uterine Fibroids · Uterine Myomas
Primary: Assessment of Menstrual Blood Flow (MBF) at 12 Months Post Procedure — 40.2; 48.8; 59.1; 67.7 Percentage of participants
N/A N=57 An Intraoperative Guidance Platform for Radio Frequency Ablation
Hepatocellular Carcinoma
Primary: Rate of Technical Success of Tumor Ablation — 68; 0 tumors
N/A N=39 A Prospective Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves Versus Facet Joint Injection of Corticosteroid for the Treatment of Lumbar Facet Syndrome
Lumbar Facet Syndrome
Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants
N/A N=8 Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
Low Back Pain
Primary: Percentage of Patients With Magnetic Resonance Imaging (MRI) Evidence of Tissue Ablation/Edema at Targeted Lumbar Medial Branches — 100 percentage of participants
N/A N=69 Dorsal Root Ganglion Thermal Radiofrequency Versus Pulsed Radiofrequency for Metastatic Pain in Thoracic Vertebral Body
Bone Neoplasm,Malignant Vertebral Column Thoracic Secondary
Primary: The European Organisation for Research and Treatment of Cancer (EORTC) Questionnaire to Measure Change in the Intensity of Pain QLQ-C30 — 41.30; 51.08; 38.76; 42.48…
Phase 2 N=107 Pilot Study of Radiofrequency Ablation of Breast Cancer Lumpectomy Sites to Decrease Re-operation
Cancer of the Breast
Primary: Number of Patients Requiring 2nd Surgery for Close or Positive Margins — 22 participants
N/A N=21 Radiofrequency of Breast Cancers in Non Surgical Patients
Breast Cancer
Primary: Number of Participants With Disease Recurrence One Year After the Intervention. — 1 Participants
Phase 1 N=57 Placebo-controlled Trial of Transdiscal Radiofrequency Annuloplasty
Lower Back Pain
Primary: Physical Function — 62.04; 48.67 units on a scale
Phase 3 N=55 AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation
Atrial Fibrillation
Primary: Percent of Patients Free From AF and Off Class I and III Anti-arrhythmic Drugs as Determined by Holter Monitoring at 6 Months. — 74 percentage of subjects
N/A N=206 OsteoCool Tumor Ablation Post-Market Study
Metastasis Spine · Metastasis to Bone
Primary: Change of Worst Pain Score: Thoracic/Lumbar Spine RF Ablation — -4.1 units on a scale — p=<0.0001
Phase 3 N=75 Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) Study
Atrial Fibrillation
Primary: Efficacy Endpoint: The Percent of Patients Off Class I and/or III Antiarrhythmic Drugs and Out of Atrial Fibrillation as Determined by 24 Hour Holter Recording Conducted…
N/A N=70 Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes
Arthroplasty, Replacement, Knee
Primary: Opioid Consumption After Surgery — 192; 144 Morphine Equivalents (ME) — p=.978
N/A N=50 RF Surgical Sponge-Detecting System on the Function of Pacemakers and Implantable Cardioverter Defibrillators
Cardiomyopathy · Cardiac Arrhythmia · Heart Failure
Primary: Pacing Mode Changes Between Permanent Pacemakers (PPMs)/Implantable Cardiac Defibrillators (ICDs) Scanned With RF Assure — 29; 29; 8; 8 participants — p=1.0
N/A N=51 Radiofrequency Ablation in Treating Patients With Stage I Non-Small Cell Lung Cancer
Lung Cancer
Primary: Overall Survival at 2 Years — 69.8 percentage of participants
N/A N=52 Treatment of Unresectable Colorectal Metastases by Radiofrequency Ablation Combined or Not With Resection, With or Without Neoadjuvant Chemotherapy.
Colorectal Cancer
Primary: Complete Hepatic Response Rate at 3 Months — 79 percentage of participants
N/A N=6 Focal Prostate Radio-Frequency Ablation
Prostate Cancer
Primary: Negative Biopsy Rate at 6 Months After Focal Bipolar Radio-Frequency Ablation (RFA) — 3; 2; 1 Participants
N/A N=13 Radiofrequency Ablation and External-Beam Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Lung Cancer
Primary: Two Year Progression Free Survival Rate — 8 participants
Phase 3 N=75 Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/Persistent
Atrial Fibrillation
Primary: Efficacy Endpoint: The Percent of Patients Off Class I or III Antiarrhythmic Drugs and Out of AF as Determined by 24 Hour Holter Recording at 9 Months — 42.6 percentage…
Phase 3 N=24 Endoscopic Biliary Co-axial Stent Placement Plus/Minus Use of Radiofrequency Ablation (RFA) for Clearance of Occluded Self Expandable Metal Stents (SEMS) in Patients With Distal Biliary Obstruction From Unresectable Biliary-pancreatic Malignancies
Pancreatic Cancer · Unresectable Biliary-pancreatic Malignancies
Primary: Rate of Failure
N/A N=15 Radiofrequency Ablation of Adenomyosis
Adenomyosis
Primary: Post-operative Evidence of Adenomyoma Tissue Ablation Effect by Area (n) as Assessed by Pathological Analysis — 9; 8; 7; 6 treated areas
Phase 3 N=167 NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation
Heart Diseases · Arrhythmia · Atrial Fibrillation
Primary: The Percentage of Chronic Success of the NAVISTAR THERMOCOOL Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation (PAF) — 66; 16 Percentage of…
N/A N=96 Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia
ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Primary: Complete Response — 81 Participants
N/A N=20 Evaluating Active Esophageal Cooling During Cardiac Ablation Procedures
Atrial Fibrillation
Primary: Total Time of Active Ablation Procedure — 3.26 Hours