Clinical Trial Search

Primary: Melasma Area Severity Assessment (MASI) Score Change From Baseline to Follow Up — -5.6; 4.7 score on a scale

Primary: Change in Melasma Area and Severity Index (MASI) Score — -11.4 units on a scale — p=0.006

Primary: Change in Spots - Front of Face (Part 1) — 53.60; 58.47; 56.44 spots

Primary: Change in Dyspigmentation Spots — 48.3; 46; 42.2; 42.5 Dyspigmentation Spots

Primary: Visual Analog Scale (VAS) of Improvement Rated by a Blinded Dermatologist From at Week 10 — 4.37; 4.62 units on a scale

Primary: Change From Baseline in Melasma Severity Rating Scale Score to Week 12 — 2.1; 2.1; -0.3; -0.8 score on a scale — p=0.041

Primary: Proportion of Patients With Moderate to Severe Hypopigmentation and Hyperpigmentation Assessed After Treatment — 0; 0 participants

Primary: Number of Participants Showing Improvement of Melasma Based on Mexameter Readings — 18 participants

Primary: Proportion of Success, Defined as Improvement of at Least 2 Grades From Baseline According to the IGA Scale Based on Facial Assessment — 16; 14.58; 11.54 Percentage of…

Primary: Efficacy Outcome — 2.31; 1.15 units on a scale

Primary: Improvement of the Inflammatory Lesions (Papules, Pustules, Nodules), Erythema, and Telangiectasia of Rosacea as Assessed by the Investigator's Global Assessment (IGA)…

Primary: Improvement in Acne Scarring - From Baseline to Three Months After Last Treatment — 2; 2 score on a scale

Primary: Complete Clearance (%) of Actinic Keratoses (AKs) — 81; 60 percentage (%) of AK clearance

Primary: Change in Overall Improvement of Poikiloderma of Civatte (POC) From Baseline at 12 Weeks — 11.01; 6.03; 8.51; 5.89 percentage

Primary: Change in Aesthetics — 2; 1 score on a scale

Primary: Change From Baseline in a* and E at 8 Weeks — 1.27; 0.43; 4.08; 2.59 units on a scale

Primary: Solar Lentigines Count — 25.7; 26.0; 8.0; 11.0 Number of solar lentigines

Primary: Change in Wrinkles From Baseline to 12 Weeks Post-study Treatment Assessed by Blinded Photographic Evaluation Using 9-Point Fitzpatrick Wrinkle Scale

Primary: IGA of Improvement — 3.1; 3.5 units on a scale

Primary: Degree of Improvement in Erythematotelangiectatic Rosacea and Papulopustular Rosacea — 2.114; 2.088 score on a scale

Primary: Investigator Global Assessment- Atopic Dermatitis — 1.7; 1.5 units on a scale

Primary: Histological Lesion Clearance — 61.5; 38.5 percentage of complete clearance — p=0.375

Primary: Mean Number of Facial Actinic Keratoses at Week 12 — 2.70 Lesions

Primary: The Absence of Lentigo Maligna (LM) at the Time of Staged Excisions in Participants — 27; 29 participants

Primary: Global Wrinkling - Change From Baseline to Week 12, Averaged Expert Grader Scores — 0.18; 0.30 Units on a scale — p=<0.001

Primary: Mean Change From Baseline in Erythema — -1.687; 5.730 units on a scale

Primary: Pigmented Lesion Improvement by Blinded Evaluation — 41 Observations

Primary: The Degree of Hyperpigmentation at 12 Weeks — 56.8; 57.6; 51.0; 54.3 score on a scale — p=0.002

Primary: Change in Patient and Observer Scar Assessment Scale (POSAS) Score From Baseline to Final Visit — -20; -20.6 score on a scale

Primary: Histological Lesion Clearance — 38.5; 69.2 percentage of complete histological clea