Clinical Trial Search

Primary: Change From Baseline Brain Activation in the Ventrolateral Prefrontal Cortex (VLPFC) Based on Change From Baseline to Week 6 in fMRI Blood Oxygen-level Dependent (BOLD)…

Primary: Positive and Negative Symptom Improvement — 41.3; 40.3; 36.6; 37.3 score on a scale

Primary: Error Percentage in Antisaccade Task — 22.6; 29.1 Error Percentage in Antisaccade Task — p=<0.05

Primary: tDCS Engagement of DLPFC Activity Indexed by fMRI BOLD Imaging

Primary: Number of Participants Demonstrating Improvement in Substance Use — 3; 3 participants

Primary: Percentage of Participants Assessed as Very Much Improved or Much Improved Based on the Clinical Global Impression-Improvement (CGI-I) Scale — 54.4; 33.1 percentage of…

Primary: Average Over Time of Intensity of Cannabis Use (Used to Evaluate Treatment Efficacy) — 0.02; 4.56 Joints per week — p=.088

Primary: Mirror-tracing Persistence (in Seconds) — 61.08; 100.34 seconds

Primary: Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 13 or Early Discontinuation — 83.5; 85.7; 6.9; -3.1 units on a scale…

Primary: End-of-session Carbon Monoxide — 62.7; 43.0 parts per million (ppm)

Primary: Change in BOLD Signal in Anterior Cingulate Cortex — -0.0188; 0.0124 BOLD signal change (Mismatch vs. Match)

Primary: Urinary Cotinine — 755; 1102; 1534; 1408 ng/ml

Primary: Working Memory — 44.8 units on a scale

Primary: PANSS Total — 77.9; 80 units on a scale — p=0.02

Primary: Brief Assessment of Cognition (BACS) Composite T Score — 37.33 Composite T- Score

Primary: Stop Signal Task (SST) — 255; 215; 297 milliseconds

Primary: Timeline Followback Assessing Number of Drinks Per Week — 35.9 Drinks per week — p=0.317

Primary: Effort-Expenditure for Rewards Task (EEfRT) Score — 0.268; 0.189 proportion of hard-task choices

Primary: Loss of Effect Over Time — 7; 15; 6; 3 Participants

Primary: Percent Change in Accuracy on High-control (i.e., Difficult) Condition of Preparing to Overcome Prepotency Task — 8.6; 9.2 percent change in accuracy

Primary: Change in NIH Examiner Flanker Task Reaction Time — -0.03; -0.12 seconds

Primary: Change in Cognition and Psychopathology Disorders as Measured on the MATRICS Consensus Cognitive Battery (MCCB) — 14.1; 14.3 units on a scale

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) - Total Score at Week 13 — 88.98; 22.468 units on a scale

Primary: Change in Positive Symptoms by Treatment Assignment — 2.222; 1.400; 1.60; 1.00 units on a scale

Primary: Change From Baseline in Days Homeless Out of the Previous 6 Months as Measured at 25 Weeks — 6.50; 9.85 days

Primary: UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) — 82.7; 84.4 units on a scale

Primary: Change in Persistent Positive Symptoms — 13; 14; 14; 14 units on a scale

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Week 24 — 72.4; -6.9 Units on a scale

Primary: Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) — 6.7; 0.9; 3.9; 5.9 T scores — p=<0.03

Primary: Effects of Nicotine Patch Compared With Placebo in Non- Smokers With Schizophrenia and Control Groups on Attention Measured by the Continuous Performance Test Identical…