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N/A N=69 Randomized Single-blind Treatment

Cognitive Training for Patients With Schizophrenia

Schizophrenia · Schizoaffective Disorder · Other Primary Psychotic Disorders

Enrolled (actual)
69
Serious AEs
0.0%
Results posted
Dec 2013
Primary outcome: Primary: UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) — 82.7; 84.4 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cognitive Training (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of California, San Diego
Primary completion
Aug 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity)
82.7; 84.4
SECONDARY
Hopkins Verbal Learning Test Percent Retained
93.4; 85.9

Summary

This research on cognitive training addresses the following questions: 1. Does cognitive training lead to improved cognition, functional abilities, psychiatric symptoms, treatment adherence, or quality of life in patients with psychoses? 2. What are the neurocognitive and non-cognitive factors that predict good outcomes following cognitive rehabilitation? In addition to verbal learning and memory, immediate verbal memory, vigilance, and executive functioning, the cognitive training intervention attempted to improve prospective memory ability (i.e., the ability to remember to do things in the future, such as take medications or attend a doctor's appointment).

Eligibility Criteria

Inclusion Criteria

  • Primary psychotic disorder (including schizophrenia, schizoaffective disorder, psychotic mood disorder, or psychosis NOS)
  • Age 18 or older
  • Fluency in English

Exclusion Criteria

  • Dementia
  • Neurological conditions affecting cognition
  • Mental retardation
  • Substance use disorder within the past month
  • Participation in other intervention trials
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01521026). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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