Phase 2 N=269 Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica
Sciatica
Primary: Oswestry Disability Index, v2 — -19.0; -13.3 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=13 Milnacipran for Lumbosacral Radicular Pain
Radicular Pain Related to Lumbosacral Disc Disease
Primary: Visual Analogue Scale Score Referring to Radicular Pain (VAS-rad) — 58.7; 67.7; 13.6; 59.7 units on a scale
N/A N=220 Management Strategies for Patients With Low Back Pain and Sciatica
Low Back Pain · Sciatica · Physical Therapy
Primary: Change From Baseline in Oswestry Disability Index — -8.8; -17.0; -17.0; -22.4 units on a scale
Phase 2 N=149 Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain
Lumbosacral Radiculopathy
Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…
Phase 3 N=82 A Trial of Corticosteroids for Low Back Pain
Radicular Low Back Pain
Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale
N/A N=63 Predictive Value of the Active Straight Leg Raise on the Efficacy of a SJB in Posterior PGP During Pregnancy
Pelvic Girdle Pain
Primary: Change From Baseline in Functioning on the Active Straight Leg Rise (ASLR) Scale at 4 Weeks. — 4.87; 2.92 score on a scale — p=<.001
Phase 3 N=84 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy
Lumbosacral Radiculopathy
Primary: Numerical Rating Leg Pain Score — 2.54; 3.56; 3.78 units on a scale
Phase 4 N=39 Efficacy of Pregabalin in Patients With Radicular Pain
Neuropathy; Radicular, Lumbar, Lumbosacral · Failed Back Surgery Syndrome · Spinal Stenosis
Primary: Pain Scores (NRS) at 3-weeks — 6; 3 units on a scale — p=0.279
N/A N=48 Additional Gluteal Control Training for Low Back Pain With Functional Leg Length Inequality
Low Back Pain, Recurrent
Primary: Leg Length Inequality — 0.3; 0.58 centemeter
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
N/A N=51 Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization
Radiculopathy
Primary: Visual Analog Scale — 5.638; 5.050; 5.094; 4.894 Centimeters
Phase 4 N=80 Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Fracture of Ankle
Primary: Quality of Recovery — 181; 184; 181 units on a scale
N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
N/A N=141 Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents
Anterior Cruciate Ligament (ACL) Tear
Primary: Pain Reduction — 1.438; 2.615 Numerical Rating Scale (NRS) — p=0.065123
N/A N=196 Efficacy of Acupuncture for Lumbar Spinal Stenosis
Lumbar Spinal Stenosis · Intermittent Claudication
Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale
Phase 4 N=84 Hip Scope Fascia-iliaca (FI) Block Study
Hip Dysplasia · Femoroacetabular Impingement · Acetabular Labrum Tear
Primary: Visual Analog Scale — 2.65; 2.50 units on a scale
Phase 3 N=991 A Study of SI-6603 in Patients With Lumbar Disc Herniation
Intervertebral Disc Disease · Lumbar Disc Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAE) — 615 Participants
N/A N=42 Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
Low Back Pain · Sciatica · Back Related Leg Pain
Primary: Number of Particpants Screened Per Month — 103 participants per month
Phase 3 N=352 SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)
Lumbar Disc Herniation
Primary: Change From Baseline to Week 13 in Average Worst Leg Pain Score During the Past 24 Hours Over the Previous 7 Days — -41.7; -34.2 units on a scale — p=0.0263
Phase 2 N=40 Effect of Milnacipran in Chronic Neuropathic Low Back Pain
Low Back Pain
Primary: Effect Size of VAS Pain — 24.8; 31.3 units on a scale
N/A N=50 Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
Postoperative Pain
Primary: Visual Analogue Scores (VAS) - Pain Scores Measured in mm (0-100) — 59.4; 30.2 units on a scale — p=0.001
Phase 4 N=29 Lumbar Stenosis Outcomes Research (LUSTOR)
Lumbar Spinal Stenosis
Primary: Time to First Symptoms of Moderate Pain — 2.52; 3.06 minutes
N/A N=50 Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery
Pain, Postoperative
Primary: Postoperative Pain During PACU Admission — 40; 36 units on a scale
N/A N=116 Peripheral Nerve Stimulation(PNS) for Subacromial Impingement Syndrome(SIS)
Shoulder Pain · Shoulder Impingement Syndrome · Shoulder Tendinitis
Primary: Change in - Short Form (SF) Question 3 (BPI-SF3) — 6.90; 7.05; 3.58; 3.96 units on a scale
Phase 4 N=122 Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
Arthritis of Hip
Primary: Averaged Pain Score — 3.75; 4.11 score on a scale
N/A N=250 Ultrasound Guided Distal Sciatic Nerve Block - a Comparison With Nerve Stimulator Technique
Other Surgical Procedures
Primary: Success Rate Without Supplementation — 112; 73 participants — p=< 0.05
N/A N=331 PROs in Chronic Low Back Pain Patients With Accompanying Lower Limb Pain (Neuropathic Component) Treated With Pregabalin
Low-Back Pain
Primary: Change From Baseline in Pain Related Sleep Interference Scale (PRSIS - Past Week Recall) — 3.1; 2.9; -1.306; -0.357 scores on a scale — p=<0.001
N/A N=30 Effectiveness of the Compression Belt for Patients With Sacroiliac Joint Pain
Low Back Pain
Primary: Oswestry Low Back Pain Questionnaire — 26.00; 24.40; 17.20; 14.67 units on a scale
N/A N=145 Steroids Versus Gabapentin
Sciatica · Radiculopathy
Primary: Average Leg Pain at 1 Month Measured Using the Numeric Pain Scale — 3.3; 3.7 units on a scale
Phase 2 N=108 Chronic Low Back Pain Research Project
Chronic Low Back Pain
Primary: Transformed Descriptor Differential Scale-Pain Intensity Scores Adjusted for Time — 0.6683; 0.6988 units on a scale — p=0.4237