Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=501 Sensitivity of the InSync Sentry OptiVol Feature for the Prediction of Heart Failure
Heart Failure, Congestive
Primary: Prediction by OptiVol of HF-related Hospitalizations With Signs and/or Symptoms of Pulmonary Congestion. — 58 hospitalization
N/A N=31 Study To Assess The Reproducibility And Sensitivity Of Quantitative Sensory Testing In Patients With Neuropathic Pain
Neuropathic Pain
Primary: Mean Change From Baseline in Dynamic Allodynia Intensity at Visits 3 and 6 and Visits 4 and 7 — -1.09; -1.16; -1.31; -0.67 scores on a scale — p=0.7319
N/A N=124 Safety Study of a Sensitive Sensual Touch and Personal Lubricant
Inadequate Lubrication
Primary: Number of Participants With Physical Irritation Scores — 61; 61; 1; 0 Participants
N/A N=67 Hearing Study: Sensitivity to Features of Speech Sounds
Hearing Loss, Sensorineural
Primary: Pure-tone Average Thresholds — 7.3; 30.8; 46.9 Hearing level in dB SPL
N/A N=79 Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Hypersensitivity
Primary: Tooth Hypersensitity to Touch Stimuli (Tactile) — 10.83; 10.63 Units on a scale — p=0.05
N/A N=28 Research Study to Determine Sensitivity to Gentle Touch and Pressure During an Active Migraine Attack.
Migraine
Primary: Proportion of Subjects With Allodynia During a Migraine Attack — 15 participants
N/A N=81 SPT for Sensitization of Collagen Dressing
Allergy Skin · Allergic Skin Reaction
Primary: Wheal Measurement — 0; 7.91; 0.32 mm
Phase 4 N=195 Dose Response of a Tubule Occlusion Agent
Dentine Hypersensitivity · Dental Pain
Primary: Adjusted Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Visual Analog Scale (VAS) at Day 15 — -26.1; -28.4; -26.2 Units on a scale — p=0.3628
Phase 2 N=201 Determination of the Sensitivity and Specificity of Prick Test Betula Verrucosa
Immune System Diseases
Primary: Sensitivity for 100 HEP/mL — 75; 0 positive reaction
Phase 1 N=259 Contact Sensitization Potential of 828 Ointment
Healthy Volunteers
Primary: Number of Participants That Exhibited a Score Less Than 1.5 on the Jordan-King Scale — 205 participants
N/A N=215 A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -2.00; -0.20 score on a scale — p=<0.0001
N/A N=56 Wetness Sensing System
System Validation
Primary: Sensor Detection — 96.15 percentage of passes
N/A N=120 Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Week 12 (Test Dentifrice Versus [vs] Negative Control Dentifrice) — -1.19; -0.44 score on a scale…
N/A N=30 A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline for Visual Analog Scale - Cold Water — -22.93 Units on a scale
N/A N=104 Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -2.25; -0.31 score on a scale — p=<0.0001
Phase 4 N=141 Study to Investigate the Efficacy of an Occluding Dentifrice in Providing Relief From Dentine Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score at Day 14 — 2.70; 2.74; -1.38; -0.10 score on a scale — p=<0.0001
N/A N=546 Evaluation of Gluma Desensitizer in Post-treatment Sensitivity in Posterior Composite
Sensitivity, Tooth
Primary: Number of Participants With Post-operative Sensitivity Having VAS Score >3 — 14; 12; 6; 16 Participants — p=0.05
N/A N=120 A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity
Dentin Hypersensitivity
Primary: Air Challenge — 1.17; 1.48; 2.26; 1.39 score on a scale
N/A N=101 Variable Perception of Cutaneous Stimulation
Pain, Acute · Anesthesia, Local · Dermatology/Skin - Other
Primary: Numeric Rating Score — 2.0; 1.2 score on a scale — p=< 0.05
N/A N=60 An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity
Tooth Sensitivity
Primary: Schiff Air Test: Mean Reduction in Sensitivity Between Groups — -0.66; -1.12; -0.52; -1.11 units on a scale — p=0.05
Phase 2 N=50 Safety, False-Positive Reactions and Sensitizing Properties of Leishmania Tropica Skin Test Antigen
Cutaneous Leishmaniasis
Primary: Sensitizing Effects of LtSTA in Leishmania Naive Adults — 8; 22; 9 participants
N/A N=36 Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
Dentin Sensitivity
Primary: Change From Baseline Air Challenge — -0.412; -0.132 Units on a scale
N/A N=113 A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Day 56 — -1.40; -0.33 score on a scale — p=<0.0001
N/A N=655 A Real-World Evidence Study to Evaluate Oral Health Related Quality of Life Using an Anti-Sensitivity Toothpaste
Dentin Sensitivity
Primary: Mean Score of DHEQ Section 1 - Impact on Everyday Life (Question [Q]1-3) at Baseline (Day 0) — 5.90; 6.17; 5.20 score on a scale
Phase 2 N=134 Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on Schiff Sensitivity Scale at Week 4 — -0.36; -0.43; -0.40; -0.45 Score on a scale — p=0.4553
Phase 3 N=39 Irritation and Sensitization of Chlorhexidine Gluconate (CHG) Cloth
Surgery
Primary: Grading Scale for Visual Evaluation of Skin Condition — 0; 0; 0; 0 Scores Ranging (0-7)
Phase 2 N=140 Exploratory Study to Evaluate the Efficacy of an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity
Dentinal Hypersensitivity
Primary: Mean Change From Baseline in Schiff Sensitivity Score at Week 4 — 2.39; 2.41; 2.40; 2.38 Score on a scale — p=0.4321
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=20 Somatosensory Profiling in Radicular Pain Patients And it's Correlation With Treatment Outcome
Radiculopathy · Lower Extremity Radicular Pain
Primary: Pre-epidural Warm Sensation Quantitative Sensory Testing (QST) Results — 2.68; 5.67 Degrees Celsius — p=.04