N/A N=28 Sex Differences in Risk for Alcohol Abuse
Alcohol Abuse
Primary: Brain Activation During Response Inhibition (BARI) - Alcohol Infusion — 1.83; 2.41 BOLD activation
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Sex Differences in Vascular Responses to Exercise
Aging
Primary: Change in FMD in Response to Chronic HIIT — 0.11; 0.57; 0.81; 0.10 % flow mediated dilation
N/A N=77 Sex Differences, Cognitive Training & Emotion Processing
Alcohol Use Disorder
Primary: Emotional Stroop: Change From Baseline in Reaction Time — 336; 162; 78.3 milliseconds — p=.0078
Early Phase 1 N=60 Individual Differences in Drug Response
Differential Female Response to Δ9-tetrahydrocannabinol (THC)
Primary: Change From Baseline in Profile of Mood States (POMS) — 2.58; 4.28; 8.25; 0.7 units on a scale
Early Phase 1 N=8 Progesterone for Cannabis Withdrawal
Cannabis Use Disorder · Cannabis Withdrawal
Primary: Change in Salivary Progesterone Level — 237.86; 97.87 pg/ml
Phase 2 N=33 Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes
Nicotine Dependence
Primary: Post- Cue Exposure Craving Nicotine Patch — 25.58; 25.6 score on a scale
N/A N=216 Sex Differences, Hormones & Smoking Cessation
Tobacco Cessation
Primary: Number of Participants With 7-day Point Prevalence Abstinence From Smoking at Week 4 — 12; 13; 9; 18 Participants
N/A N=19 Sex and Obesity: Effects on Heart Failure Study
Obesity · Heart Failure
Primary: Average Myocardial Blood Flow — 0.73; 0.97 mL/g/minute — p=<0.005
N/A N=169 Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes
Cigarette Smoking-Related Carcinoma
Primary: Cigarettes Per Day — 14.20; 4.08; 4.55; 14.09 Cigarettes per Day
N/A N=58 Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers
Sex · Cigarette Smoking
Primary: Glutamate in the Dorsal Anterior Cingulate Cortex — 8.11; 7.05 Institutional Units — p=0.027
Phase 4 N=23 Kaletra Sex/Gender Pharmacokinetics (PK) Study
HIV Infections
Primary: 24-hr LPV AUC — 142,160; 152140 ng*hr/mL
Early Phase 1 N=26 Sex Differences in the Dilatory Response of Compound 21
Sex Differences
Primary: Microvascular AT2R Sensitivity Following Local Control Treatment — 15; 25 percentage of maximal blood flow
N/A N=10 4 mA tDCS, Estrogen, and Leg Muscle Fatigability
Healthy
Primary: Fatigue Index From the Isokinetic Fatigue Test — 61.7; 46.7; 57.28; 55.90 Percent decline — p=<0.05
Phase 2 N=38 Sex/Gender Differences in Risk and Resilience to PTSD; Implication of Oxytocin
PTSD
Primary: Change in Amygdala Activation- Oxy Minus Placebo — -0.01; -0.02; 0.05; 0.21 percentage of BOLD signal change
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=291 Gender-Responsive Treatment for Women Offenders - 1
Substance Abuse Problem
Primary: Results (Unadjusted) for Criminal Activities in Past 30 Days at Baseline and Follow-up for Women in Women-Only Treatment and Mixed-Gender Treatment — 63.9; 76.9; 22.3…
N/A N=124 Examining the Effect of the Nicotine Patch in Male and Female Smokers - 3
Drug Addiction · Smoking Cessation
Primary: Subjective Effects — 18.8; 23.1; 25.6; 24.2 units on a scale
N/A N=61 Sex Steroids, Sleep, and Metabolic Dysfunction in Women
Polycystic Ovary Syndrome (PCOS) · Obstructive Sleep Apnea · Obesity
Primary: Very-Low Density Lipoprotein-Triglyceride (VLDL-TG) Secretion Rate — 3.13; 2.03; 4.66; 3.36 umol/min/L plasma — p=0.85
N/A N=1,105 Female Patient Preferences Regarding Physician Gender
Female Patient Preference
Primary: Proportion of Female Respondents Having Their Preferences Based on Physician Gender for the OB/GYN Care — 667; 87; 261 Participants
N/A N=100 Estradiol Effects on Alcohol Across the Menstrual Cycle
Alcohol Use, Unspecified
Primary: Attentional Bias (Early Follicular Phase) — 347.99; 355.02 milliseconds
N/A N=102 Exploring the Modulatory Role of Sex Hormones Along the Neuromechanical Axis in Females
Role of Sex Hormones Along the Neuromechanical Axis
Primary: Changes in Short-interval Intracortical Inhibition (SICI) During the Follicular Phase — 0.78; 0.83; 0.93; 1.03 ratio to the unconditioned stimulus MEP — p=>0.05
N/A N=25 Androgen Effects in HIV-infected Women
HIV Infection
Primary: Lean Body Mass — 1.8; 0.8 kilograms — p=0.04
N/A N=49 Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers
Nicotine Dependence
Primary: Percent Change in Binding Potential of Dopamine Release During PET Scan Post Amphetamine Administration — 14; 11.2; 1.9; 9.3 percentage change in binding potential
Phase 4 N=46 Unique Effects of Perimenstrual Estradiol or Progesterone Supplementation on Perimenstrual Suicidality
Suicidal Ideation
Primary: Cyclical Change in Suicidal Ideation (SI) Severity — -.22; -.05; .25 units on a scale — p=.002
N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
Phase 2 N=23 Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
Perinatal Depression · Post Partum Depression · Depression, Postpartum
Primary: Mean Threat Processing Bias During Visual Dot-probe Paradigm Over Time — -0.57; 36.92; -9.04; -42.35 attention bias in milliseconds — p=0.160
Phase 4 N=124 Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental Approach
Suicidal Ideation
Primary: Perimenstrual Change in Daily Adult Suicidal Ideation Questionnaire (ASIQ) Scores — .178; -.051 Mean Score Change — p=<.001
Phase 2 N=95 Smoking, Sex Hormones, and Pregnancy
Nicotine Dependence · Contraception
Primary: Change in Smoking Urges — 5.0; 5.5 score on a scale
Phase 2 N=92 The Effects of Reproductive Hormones on Mood and Behavior
Healthy Volunteers
Primary: Mean Beck Depression Inventory Score — 1.4; 1; 1.1 Units on a scale
Phase 4 N=64 Perimenopausal Effects of Estradiol on Reward Responsiveness
Perimenopausal Depression
Primary: Caudate Signal Intensity in Response to Reward During the MID fMRI Task at Pre-treatment — .027; .043 percent signal change — p=.620