N/A N=50 Thermage CPT for Treatment of Facial and Neck Laxity
Skin Aging
Primary: Improvement in Laxity — 0.6; 1.0; 0.9; 1.3 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=25 Clinical Study on the Application of a Non-Invasive Micro-Focused Ultrasound With Visualization System for Skin Laxity (ULT-215)
Facial Skin Laxity
Primary: Number of Participants With Improvement in Skin Laxity in Submental Region and Neck at Day 90 — 8 Participants
N/A N=52 Lifting and Tightening of the Face in Subjects With Skin of Darker Color
Facial Skin Laxity
Primary: Change in Overall Lifting and Tightening of Treated Tissue
N/A N=25 Quantitative Evaluation of Skin Shrinkage Caused by a Non-invasive Tightening Device
Healthy
Primary: The Change in Skin Tightening in the Upper Inner or Outer Arm (as Measured by Millimeters) — 45.17 millimeters
N/A N=201 Evaluation of the Effectiveness and Safety of the Ulthera® DeepSEE® System for Treating Skin Laxity in the Lower Face and Submentum
Improvement in Skin Laxity of the Lower Face and Submentum
Primary: Percentage of Subjects With Improvement in Lower Face and Submental Skin Laxity at Day 90 — 54.2; 47.0 percentage of subjects
N/A N=14 Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery
Skin Laxity · Tissue Degeneration · Tissue Breakdown
Primary: Analysis of Elasticity (Collagen & Elastin) — 1.7; 0.5; 1.5; 0.5 units on a scale
N/A N=48 Change in Skin Elasticity With RF and PEMF
Skin Abnormalities
Primary: Change in Facial Skin Elasticity — 0.7658; 0.7244 ratio
N/A N=32 Lifting and Tightening of the Face and Neck Following an Increased Density Treatment
Skin Laxity
Primary: Improvement in Overall Lifting and Tightening of Skin — 48 percentage of participants improved
N/A N=20 Radio Frequency Microneedling for Suprapatellar Skin
Skin Laxity
Primary: Photographic Knee Laxity and Texture Evaluation — 1.87; 2.02 score on a scale
N/A N=11 Radiofrequency and Pulsed Electromagnetic Field Treatment of Skin Laxity of the Mon Pubis, Labia and Vaginal Introitus
Skin Laxity
Primary: General Skin Appearance of Mons Pubis and Labia — 3; 4; 1 Participants
N/A N=10 Evaluation of the Use of the Renuvion APR System in the Labia
Labia Enlarged · Labium; Hypertrophy
Primary: Evaluation of Change Between Baseline and Follow-up Images as Determined by a Masked, Qualitative Assessment of Photographs at 90-days and 180-days Post-treatment…
N/A N=82 Renuvion APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region
Lax Skin
Primary: Day 180 Number of Participants With Improvement Measured By Independent Photographic Review — 6; 52 Participants — p=<0.0001
N/A N=5 Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
Tissue Pain
Primary: Skin Stretch Response to Manual Lateral Pull — 0.512; 0.494; 0.508; 0.473 %/mm
N/A N=30 Ultherapy™ Treatment Following Sculptra® Treatment
Skin Laxity
Primary: Lifting and Tightening of Skin as Determined by Masked Assessment of Pre- and Post-treatment Photographs. — 40; 30; 33 percentage of participants improved
N/A N=17 Effect of a Basic Skin Care Product on the Structural Strength of the Skin
Healthy Skin
Primary: Blistering Time (Full Blister) — 63; 54; 65; 62 Minutes
N/A N=103 Evaluation of the Ulthera™ System for Obtaining Lift and Tightening of the Cheek Tissue
Mild to Moderate Skin Laxity on Cheek · Mild to Moderate Skin Laxity on Upper Neck · Mild to Moderate Subcutaneous Fat on Cheek
Primary: Change in Overall Lifting and Tightening of Treated Tissue on the Lower Face and Submental Regions. — 68.60 percentage of participants improved
N/A N=15 Clinical Assessment of Skin Tightening and Contour Change of Submental Tissue Using Bipolar Radiofrequency Microneedling
Skin Laxity
Primary: Percent Change From Baseline of Soft Tissue Surface Area — -0.18; -017 percent change
Phase 4 N=25 Changing in Skin Physiology After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces
Aging
Primary: Hydration Level — 53.19; 46.75 AU (arbitrary unit) — p=<0.05
N/A N=22 Evaluation of the Candela 1064nm:Nd:YAG Laser for Skin Tightening
Localized Lipodystrophy
Primary: Number of Participants With Mild to Moderate Reduction in Cellulite. — 3; 2 participants
N/A N=45 Scleroderma ARFI Imaging of the Skin
Scleroderma
Primary: Mean Skin Stiffness — 2.68; 2.07; 2.23; 2.27 meters per second — p=0.005
N/A N=72 Safety and Effectiveness Evaluation of the Device in Achieving Submental Lift
Skin Laxity
Primary: Tissue Lift at the Submental Area Measuring >/= 20 mm2 — 56.9 percentage of participants — p=0.05
N/A N=85 Treatment With the Evoke System for Facial and Submental Laxity
Laxity; Skin
Primary: Evaluate Change in Skin Appearance — 80.7 percentage of participants
N/A N=20 Evaluation of CoolSculpt Combining Venus Legacy Technology for Enhanced Results in Fat Reduction & Laxity of the Flanks
Adipose Tissue
Primary: General Improvement in Skin Laxity of the Flank Area — 1.1; 2.1 units on a scale — p=<0.01
N/A N=64 Lifting and Tightening of the Face and Neck Utilizing the Ulthera® System
Facial and Neck Skin Laxity
Primary: Improvement in Overall Lifting and Tightening of the Jowls and/or Neck Laxity — 22; 10; 1; 11 participants
N/A N=4 Study of Skin and Muscle Parameters Using a Skin Sensor
Skin Wounds
Primary: Measure Temperature at 3 Time Points — 29.89; 31.13; 31.87; 32.02 Degrees Celsius — p=<0.0001
Phase 2 N=35 CCH Treatment of Cellulite in the Presence of Dermal Laxity With Comparison Between Two (2) Different Injection Techniques
Edematous Fibrosclerotic Panniculopathy · Cellulite · Laxity; Skin
Primary: Percentage of 1-Level Responders (+1 or Better Score) on the Investigator-Global Aesthetic Improvement Scale (I-GAIS) for Either Buttock or Either Thigh — 85.7; 87.5…
N/A N=37 Evaluation of the Ulthera® System for Treatment of the Brachia
Brachial Ptosis
Primary: Improvement in Obtaining Lift and Tightening of Brachial Skin Laxity — 48 percentage of participants improved
Phase 4 N=34 Retinol on Human Skin Aging in East Asian Descent
Intrinsic Aging of Skin
Primary: Number of Genes Upregulated or Downregulated as Assessed by RNA Sequencing (Older Group, Retinol Versus Placebo) — 23; 21 genes
Early Phase 1 N=15 Topical Bimatoprost for Chemical Blepharoplasty
Dermatochalasis
Primary: Graded Change in Dermatochalasis — .2679 units on a scale
N/A N=15 Effects of Different Support Surfaces on the Properties Skin After Loading
Pressure Ulcers
Primary: Transepidermal Water Loss (TEWL) in g/m2/h on Sacrum, at Baseline — 7.8; 7.7; 7.1 g/m2/h