N/A N=144 Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Sleep Apnea, Obstructive
Primary: Subjective Sleepiness — 11.8; 10.2; 9.9 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=42 Sleep-Disordered Breathing in Chronic SCI
Spinal Cord Injury · Sleep Apnea, Obstructive
Primary: Cognitive Functioning as Measured by PASAT — 10.6; 15.2 score on a scale
N/A N=63 Treatment of Sleep-disordered Breathing in Patients With SCI
Spinal Cord Injury · Sleep-disordered Breathing · Spinal Cord Disease
Primary: PAP Adherence — 22.03; 18.54 nights
N/A N=74 Sleep Disordered Breathing and Chronic Pain
Sleep Apnea Syndromes
Primary: Number of Sleep Related Events Per Hour — 38.8; 17.4; 4.5; 7.6 events/hour — p=<0.001
Phase 4 N=6 Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients
Heart Failure · Sleep Apnea Syndromes
Primary: Reduction in Episodic Oxygen Desaturation
N/A N=186 Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study
Sleep Disordered Breathing · Obstructive Sleep Apnea · Snoring
Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54
N/A N=153 Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Sleep Apnea Syndromes · Oxidative Stress · Cardiovascular Diseases
Primary: F2-isoprostanes/Cr — -0.02; -0.08 ng/mg — p=0.38
N/A N=89 Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP)
Obese · Pregnancy · Sleep Disordered Breathing
Primary: Uterine Artery Doppler Mean Pulsatility Index -by Ultrasound — 1.0; 1.0; 1.0; 1.0 Mean PI
N/A N=6,876 Sleep-Disordered Breathing in Heart Failure - The SchlaHF-Registry
Congestive Heart Failure · Left Ventricular Systolic Dysfunction
Primary: Prevalence of SDB in Chronic HF Patients — 3190 Participants
N/A N=34 Positive Airway Pressure Program
Sleep Apnea, Obstructive
Primary: Participant Providing Feedback — 26 Participants
N/A N=23 Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Down Syndrome · Obstructive Sleep Apnea Syndrome
Primary: Change in Epworth Sleepiness Scale From Baseline to End of Study — -1; -0.5; 1 units on a scale
N/A N=74 Home-Based Diagnosis and Management of Sleep-Related Breathing Disorders in Spinal Cord Injury
Obstructive Sleep Apnea · Hypercapnia · Spinal Cord Injury
Primary: Prevalence of Sleep-disordered Breathing in Spinal Cord-injured Adults — 40; 23; 11 participants
N/A N=169 Sleep Apnea Intervention for Cardiovascular Disease Reduction
Obstructive Sleep Apnea
Primary: Change From Baseline in 24-hour Blood Pressure at Months 6 and 12 by Pooled Arms — 1.82; 1.06; 0.59; -0.73 mmHg
Phase 2 N=13 DAW1033B2 in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA)
Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 33; 20.4 events/hour of sleep — p=0.47
Phase 2 N=11 DAW1033D in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA)
Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 21.6; 37.9 events/hour of sleep — p=0.56
N/A N=40 Sleep Apnoea Breathing Record Exploratory Study (SABRES)
Sleep Apnea
Primary: Correlation Between the Trial Device and an Established Device — 0.955 correlation coefficient
N/A N=29 Sleep-Disordered Breathing and PAP in Perinatal Depression
Sleep-disordered Breathing · Major Depressive Disorder
Primary: Change in Hamilton Rating Scale for Depression (HRSD) Score, Minus the Sleep Item — -7.62; -5.92; -8.21; -6.18 change in score — p=.367
Early Phase 1 N=63 Respiratory and Autonomic Plasticity Following Intermittent Hypoxia
Sleep Apnea Syndromes
Primary: Ventilation (Aim 1) — 1.19; 1.14; 1.35; 1.16 fraction of baseline — p=0.001
N/A N=38 Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease
Parkinson's Disease · Sleep Disordered Breathing
Primary: Tests to Determine the Apnea-hypopnea Index (Number of Apneas and Hypopneas Per Hour of Sleep) — 5.2; 20 apnea hypopnea index
N/A N=36 Incidence of Sleep-disordered Breathing and Upper Airway Collapsibility in Postpartum Patients and Its Intervention
Sleep Disordered Breathing · Upper Airway Collapsibility · Upper Airway Obstruction
Primary: Apnea-hypopnea Index (AHI), Defined as the Number of Apneas and Hypopneas Per Hour of Sleep — 4.5; 7.7 Apneas and hypopneas per hour of sleep
N/A N=25 Atrial Fibrillation Recurrence in Sleep Apnea
Sleep Apnea · Atrial Fibrillation
Primary: Number of Subjects Who Had Atrial Fibrillation Recurrence at 1 Year — 3; 3 participants
N/A N=29 Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment
Apnea, Sleep · Chronic Fatigue Syndrome
Primary: Change of Fatigue Symptom — 2.1; 0.2 units on a scale — p=0.0002
N/A N=25 The Role of Oxidative Stress in the Cardiovascular Consequences of Sleep Apnea
Sleep Apnea
Primary: Flow Mediated Dilation — 5.7; 9.5; 7.3 percentage change of vessel diamter — p=0.02
N/A N=124 Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure
Preeclampsia · Hypertension
Primary: Nocturnal Blood Pressure — 128.2; 124.7; 70.6; 68.8 mmHg — p=0.45
Phase 3 N=240 Effect of Self-Management on Improving Sleep Apnea Outcomes
Sleep Apnea Syndromes
Primary: CPAP Adherence — 2.8; 3.9 hours per night — p=0.001
N/A N=22 Combination Therapy to Treat Sleep Apnea
Sleep Apnea, Obstructive
Primary: Model Prediction of Absence/Presence of OSA: Ventilation That Causes an Arousal From Sleep (Varousal) — 5.7; 5.2 L/min — p=0.05
N/A N=104 Lifestyle Modification Program to Treat Obstructive Sleep Apnea Patients
Obstructive Sleep Apnea
Primary: Apnea-hypopnea Index (AHI) at One Year — 35.3; 39.6 events per hour
N/A N=115 Comparison of Breathing Event Detection by a Continuous Positive Airway Pressure Device to Clinical Polysomnography
Sleep Apnea
Primary: Apnea-hypopnea Indices (AHI) as Determined by Polysomnography (PSG) vs Automatic Event Detection (AED ) Algorithm — 5.6; 5.8; 2.4; 3.2 events per hour — p=0.007
N/A N=819 Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance
Obstructive Sleep Apnea Syndrome · Restless Leg Syndrome
Primary: Prevalence of Obstructive Sleep Apnea Syndrome in Chinese Elderly — 15 % of participants — p=<0.05
Phase 4 N=14 Sleep and Breathing in the General Population - Chemical Stimuli
Sleep-disordered Breathing
Primary: The Central Apnea-hypopnea Index — 14.1; 29.9 events per hour