Early Phase 1 N=18 Ketamine Infusion for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Visual Analogue Scale for Anxiety Symptoms (VAS-anxiety) — 12.1; 19.6 units on a scale
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N/A N=41 Computer-Based Treatment for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change in Percent Dwell Time on Threat Faces — 20.7; 27.1 percentage of dwell time on threat faces
N/A N=250 1/2 A Multi-site Systems Intervention for Unemployed Persons With Social Anxiety
Social Anxiety
Primary: Liebowitz Social Anxiety Scale — 81.05; 82.74; 64.11; 73.05 score on a scale
N/A N=90 Treatment of Social Anxiety Disorder and Selective Mutism
Social Anxiety Disorder · Selective Mutism
Primary: Change in Clinical Severity Ratings (CSR) of SAD & SM on the Anxiety Disorders Interview Schedule - Parent Version (ADIS-P) — -1.26; -1.65; -1.51; -1.24 units on a scale…
N/A N=48 Attention Disengagement Training for Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 68.1; 74.5; 60.0; 46.1 units on a scale
Phase 2 N=151 A Phase 2 Study of BNC210 for the Acute Treatment of Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change From Baseline to the Average Subjective Units of Distress Scale (SUDS) Score of the 5-minute Performance Phase of a Public Speaking Challenge — 22.42; 24.26…
Phase 2 N=83 SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
Phase 2 N=149 A Safety and Efficacy Study of JNJ-42165279 in Participants With Social Anxiety Disorder
Phobic Disorders
Primary: Change From Baseline in Liebowitz Social Anxiety Scale (LSAS) Total Score — -22.4; -29.4 units on a scale
Phase 4 N=30 Escitalopram in Patients With Social Anxiety Disorder
Social Anxiety Disorder
Primary: Effect of Escitalopram After 12 Weeks Using the Clinical Global Impression (CGI-I) — 2.1 scores on a scale
Phase 4 N=63 12-Week Study of Pristiq (Desvenlafaxine) Social Anxiety Disorder
Social Anxiety Disorder
Primary: Change in the Liebowitz Social Anxiety Scale (LSAS) Total Score — 93.4; 92.1; 55.0; 63.4 Scores on a scale
N/A N=56 A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder.
Social Anxiety Disorder (SAD)
Primary: Measurement of Intervention Credibility Assessed With the Credibility Score, at Baseline — 18; 15.4 units on a scale — p=0.1134
N/A N=44 Efficacy of Virtual Reality Exposure Therapy Scripts for Social Phobia
Social Anxiety Disorder
Primary: Change From Baseline in the Social Phobia Diagnostic Questionnaire (SPDQ) at Post-treatment — -9.60; -4.46 score on a scale — p=< 0.05
Phase 3 N=27 Efficacy and Tolerability of Atomoxetine (Strattera) in Adult Patients With Generalized Social Anxiety Disorder
Generalized Social Phobia
Primary: Clinical Global Impression (Change Version, Also Known as Improvement Version) — 3; 4 participants
N/A N=53 Attention, Teleconferencing and Social Anxiety
Social Anxiety Disorder
Primary: Personal Report of Communication Apprehension Questionnaire — 88.06; 87.64; 95.69 score on a scale
Phase 3 N=224 PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
Social Anxiety Disorder
Primary: Subjective Units of Distress Scale (SUDS) Score — 77.7; 78.2; 62.3; 61.3 score on a scale — p=.5063
Phase 1 N=61 Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)
Seasonal Affective Disorder · Depression
Primary: Scores on the Structured Interview Guide for the Hamilton Depression Rating Scale-Seasonal Affective Disorder Version — 13.6; 13.3; 8.3; 22.6 units on a scale
N/A N=106 Assessment and Treatment of Social Skills Deficits in Individuals With Social Phobia
Social Phobia
Primary: Social Phobia Remission
Phase 2 N=51 Geodon for the Treatment of Refractory Social Anxiety Disorder
Social Anxiety Disorder
Primary: Brief Social Phobia Scale(BSPS) — 44.0; 31.8; 31.8; 31.2 units on a scale — p=< 0.001
Phase 4 N=169 D-Cycloserine Enhancement of Exposure in Social Phobia
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 39.19; 42.44 units on a scale
N/A N=49 Interpretation Modification Program for Social Phobia
Social Anxiety Disorder · Social Phobia
Primary: Liebowitz Social Anxiety Scale (LSAS) — 82.0; 77.7; 50.2; 67.6 units on a scale
Phase 3 N=61 Adding Cognitive Behavioral Therapy to Drug Treatment for Social Anxiety Disorder
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 7.77; 7.84 units on a scale — p=.267
N/A N=89 Social Phobia Intervention Study of Mannheim
Social Phobia
Primary: Change From Baseline in Social Interaction Anxiety Scale (SIAS) — 43.13; 48.94; 34.85; 33.35 units on a scale — p=<0.05
Phase 3 N=370 Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
Social Anxiety Disorder
Primary: Change From Baseline to the Average Subjective Units of Distress Scale (SUDS) Score of the 5-minute Performance Phase of a Public Speaking Challenge — 27.2; 26.0 score…
N/A N=76 Internet Treatment for Social Phobia in Romania
Phobia, Social
Primary: Leibowitz Social Anxiety Scale - Self Report (LSAS-SR) — 78.60; 78.47; 73.69; 43.98 units on a scale — p=<0.01
Phase 3 N=22 Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder
Social Anxiety Disorder · Performance Anxiety
Primary: VAS-anxiety Immediately After the Impromptu Speech Task — 54.3; 62.6 millimeters (units on a scale) — p=0.056
N/A N=75 Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Social Anxiety Disorder · Social Anxiety · Social Anxiety Disorder of Childhood
Primary: Self-reported Affective Experience — 10.19; 10.00; 10.28; 8.33 units on a scale — p=.723
Phase 4 N=42 Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism
Social Anxiety Disorder · Social Phobia · Alcohol Use Disorder
Primary: Social Anxiety Severity — 87; 93 units on a scale
N/A N=24 Wiring Adolescents With Social Anxiety Via Behavioral Interventions
Social Anxiety
Primary: Ecological Momentary Assessment (EMA) Adherence — 53 percentage of participants
Phase 3 N=28 Duloxetine for Social Anxiety Disorder: Prediction of Long Term Outcome
Anxiety Disorder
Primary: Anxiety Symptoms as Assessed by Liebowitz Social Anxiety Scale — 67.9; 53.7 Scores on a scale — p=<0.132
N/A N=73 Hormones and Social Anxiety Disorder Treatment
Social Anxiety Disorder
Primary: LSAS-performance Subscale — 34.04; 32.54; 32.05 units on a scale