N/A N=118 ViBone in Cervical and Lumbar Spine Fusion
Spondylosis · Cervical Spondylosis · Spondylolisthesis
Primary: Fusion Rates Per Level Using the Bridwell Interbody Grading Scale — 64; 50 Fusions
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=85 Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
Intervertebral Disk Degeneration · Intervertebral Disk Displacement · Ossification of Posterior Longitudinal Ligament
Primary: Bone Fusion With CT(Postoperative 6 Months) — 26; 28 participants
N/A N=36 Accell Evo3™ Demineralized Bone Matrix in Instrumented Lumbar Spine Fusion
Degenerative Changes · Stenosis · Spondylosis
Primary: Time to Arthrodesis (Fusion) for Each Spinal Level (Unit), as Measured by X-rays. — 6 months to fusion
N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
Phase 2 N=86 TXA in Spinal Fusion
Degenerative Disc Disease
Primary: Transfusion — 7; 6; 9; 8 Participants
N/A N=17 Prospective Study of Thoracolumbar Spinal Fusion Graft
Lumbar Degenerative Disc Disease
Primary: Spinal Fusion Grade at 1 Year Via CT Scan — 1.67; 2.4 score on a scale
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=53 Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
Lumbar Degenerative Disc Disease · Lumbar Spinal Stenosis · Lumbar Spondylolisthesis
Primary: Interbody Radiographic Fusion Rate — 27; 10; 6; 24 Cages/Spinal Levels
N/A N=710 INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical Trial
Degenerative Disc Disease
Primary: Rate of Overall Success — 80.9; 59.9 percentage of participants — p=<0.001
N/A N=184 Understanding Non-Response in Spine Fusion Surgery
Spine Fusion
Primary: Oswestry Disability Index — 41.3; 30.4; 19.4 score on a scale
N/A N=194 Sacroiliac Joint Fusion With iFuse Implant System (SIFI)
Degenerative Sacroiliitis · Sacroiliac Joint Disruption
Primary: Subject Success — 80.5 percentage of participants
N/A N=252 A Prospective, Multicenter Observational Study on MAST™ (Minimal Access Spinal Technologies) Fusion Procedures for the Treatment of the Degenerative Lumbar Spine
Degenerative Lumbar Spine Causing Back and/or Leg Pain · Lumbar Spine Degeneration
Primary: Time From Surgery to First Ambulation. — 1.3 Days from surgery to first ambulation
Phase 4 N=36 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion
Lumbar Spondylosis · Lumbar Spondylolisthesis · Adult Degenerative Lumbar Scoliosis
Primary: Quality of Spine Fusion, Measured by the Number of Participants With Complete Spine Fusion at 1 Year — 11; 6 Participants
N/A N=20 Clinical and Radiological Evaluation of Patients With DDD Following TLIF With 3-D Printed Titanium Cage
Intervertebral Disc Disease
Primary: Fusion Rate — 19; 1; 0 Participants
N/A N=22 Assessment of nanOss Bioactive 3D in the Posterolateral Spine
Degenerative Disc Disease · Spinal Stenosis · Spondylolisthesis
Primary: Number of Patients With Fusion — 16 Participants
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
N/A N=69 Anterior Bridging Cage With Bone Substitute Versus Localized Autobone in Transforaminal Lumbar Interbody Arthrodesis
Stenosis · Fusion of Spine (Disease)
Primary: InCBB of Both Cages — 1.48; 1.43 score on a scale
N/A N=178 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Lumbar Osteoarthritis · Spondylosis · Lumbar Disc Disease
Primary: Perioperative Opioid Use — 86.25; 306.6; 192.4; 88.95 oral morphine equivalents (OME) (mmg) — p=<0.001
N/A N=51 Spinery® A Novel Radio-Frequency Tumor Ablation Device for Spine Metastatic Tumors
Vertebral Metastasis
Primary: Change From Baseline in Worst Pain and Quality of Life Scores at 3 Months Using the Brief Pain Inventory (BPI) and EQ-5D-5L Questionnaires — 3.4; 65.2 points on a…
Phase 4 N=20 BIO4 Clinical Case Study: Cervical Spine
Degenerative Disc Disease · Trauma (Including Fractures) · Spondylolisthesis
Primary: Radiological Assessment : Fusion Status — 20 participants
N/A N=29 OsteoStrux™ Collagen Ceramic Scaffold in Instrumented Lumbar Spine Fusion
Degenerative Changes · Stenosis · Spondylosis
Primary: Number of Posterolateral Gutters That Have Evidence of Arthrodesis (Fusion) at 3, 6, 12, and 24 Months, as Measured by X-rays. — 39; 34; 42; 36 Posterolateral Gutters
N/A N=30 Complementary Therapies in Spinal Fusion Patients
Idiopathic Scoliosis
Primary: Postoperative Pain (Total Opioid Use) — 0.041; 0.048; 0.054; 0.038 mg/kg/hr
N/A N=43 Efficacy and Safety of Accell Evo3 Demineralized Bone Matrix (DBM) in Instrumented Posterolateral Lumbar Spine Fusion
Stenosis · Spondylosis · Degenerative Changes
Primary: Number of Radiographic Assessments That Indicate Posterolateral Fusion at 12 Months Post Surgery — 43; 74 radiographic assessments
N/A N=60 Efficacy and Safety of Integra Accell Evo3 DBM in Instrumented Lumbar Spine Fusion
Stenosis · Spondylosis · Degenerative Changes
Primary: Number of Levels With Posterolateral Fusion — 23; 26 levels
N/A N=390 A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis
Lumbar Spinal Stenosis
Primary: Measure of Pain/Disability Using the Zurich Claudication Questionnaire (ZCQ) Physical Function Score — 1.7; 1.6; 1.7 score on a scale
N/A N=129 Retrospective Review of Integrity Implants FlareHawk® for Lumbar Fusion
Degenerative Disc Disease
Primary: Radiographic Arthrodesis — 56 Participants
N/A N=104 Prospective, Multi-Center Clinical Outcomes Study Evaluating the chronOS Strip Combined With Bone Marrow Aspirate
Degeneration of Lumbar Intervertebral Disc
Primary: Posterolateral Fusion Success — 45 participants
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
N/A N=322 Post-Approval Clinical Trial Comparing the Long Term Safety and Effectiveness Coflex vs. Fusion to Treat Lumbar Spinal Stenosis
Spinal Stenosis
Primary: Number of Subjects With Improvement of at Least 15 Points in ODI — 41; 101 Participants
N/A N=44 Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease
Lumbar Spondylolisthesis · Degenerative Disc Disease · Degenerative Spondylolisthesis
Primary: Incidence of Successful Lumbar Fusion Measured Radiographically — 13; 11 Participants