N/A N=131 Subchondroplasty® Knee RCT
Bone Marrow Edema · Knee Pain Chronic · Knee Osteoarthritis
Primary: Composite Clinical Success — 68; 38; 16; 4 Participants — p=>0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=15 Intra Articular Injections With Platelet Rich Plasma in Patients With Juvenile Osteochondritis Dissecans of the Knee
Osteochondritis Dissecans
Primary: Greater Cartilage Healing Measured by Glycosaminoglycan Content on dGEMRIC MRI
Phase 3 N=194 Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI
Knee Osteoarthritis
Primary: Cartilage Volume Loss of the Lateral Compartment — 6408; 6196; 6196; 6143 cubic milimeters
Phase 2 N=102 Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee
Osteoarthritis, Knee
Primary: Change From Baseline in the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score at 1 Year — 23.3; 9.9 scores on a scale — p=<0.01
N/A N=30 Management of Traumatic Bone Defects in Tibial Plateau Fractures With Antibiotic-Impregnated Biodegradable Calcium Sulfate Beads: A Prospective Clinical Trial
Tibial Fractures · Intra-Articular Fractures · Fracture Fixation, Internal
Primary: Resorption of Study Device — 4 Participants
Phase 3 N=118 RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee
Articular Cartilage Lesion of the Femoral Condyle
Primary: Histomorphometry Safranin-O + Anti-Collagen II Antibody Staining — 1.01; 0.75 Ratio — p=0.003
N/A N=73 Real-world Evidence Study on Cystistat
Interstitial Cystitis and Bladder Pain Syndrome
Primary: Patient Global Assessment (PGA) — 90.1 percentage of participants (%)
N/A N=101 Role of Bone in Knee Osteoarthritis (OA)
Osteoarthritis, Knee
Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants
N/A N=150 The Effect of Bone-void Filler on Anterior Knee Pain Following ACL Reconstruction
ACL
Primary: Score on Knee Injury and Osteoarthritis Outcome Score (KOOS) Survey — 67; 69; 67.7 score on a scale
N/A N=24 Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects
Cartilage Loss · Microfracture
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) (Clinical Outcome) — 12.0; 4.1; 19.1; 8.1 units on a scale — p=0.162
N/A N=25 Study of Cingal® for Symptomatic Relief of Osteoarthritis of Ankle Joint
Osteoarthritis, Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.84 units on a scale — p=<0.0001
N/A N=77 SCP Hip Outcomes Study
Subchondral Cysts · Subchondral Bone Edema · Bone Marrow Edema
Primary: Overall Group Mean Improvement From Baseline of the Modified Harris Hip Score (mHHS) at 2 Years — 25.8; 26.3; 24.8 score on a scale
Phase 3 N=163 Efficacy Study of Condrosulf in the Treatment of Symptomatic OA of the Hand
Osteoarthrosis
Primary: Change in Global Spontaneous Pain Intensity of Target Hand — -20; -11.3 mm — p=0.016
Phase 4 N=150 Effects on the Pain of an Infiltration by Acid Hyaluronic Association and Corticoids Versus Only Corticoids in the Rhizarthrosis.
Rhizarthrosis
Primary: Analogical Visual Scale of Pain (VAS) — -1.66; -2.65 centimeter
Phase 2 N=35 IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Foreign-Body Reaction · Inflammation · Effusion (L) Knee
Primary: Safety: Adverse Events — 0 participants
N/A N=121 MRI of Infrapatellar Fat Pad in Osteoarthritis
Osteoarthritis
Primary: Infrapatellar Fat Pad Volume in MRI — 25154.96; 29202.39 mm^3
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
Phase 4 N=40 Comparison of Excision Versus Punch Incision in the Treatment of Epidermal Cysts
Epidermal Cyst
Primary: Number of Participants With Cyst Recurrence — 3; 2 participants
N/A N=24 Euflexxa for the Treatment of Osteoarthritis
Osteo Arthritis Knee
Primary: Change in Hyaluronate Concentration — 0.29568 mg/ml
N/A N=57 Intra-articular Polyacrylamide Hydrogel in the Treatment of Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in the Total WOMAC Score (WOMAC-T) — 1137.13; 767.47; 1271.60; 445.33 score on a scale — p=0.00
Phase 2 N=20 Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
Tibial Meniscus Injuries · Osteoarthritis, Knee
Primary: Change in Numerical Pain Scale — -3.2 units on a scale
N/A N=79 Using Ultrasound to Predict Response to Intraarticular Corticosteroids in Knee Osteoarthritis
Osteoarthritis
Primary: Change in Western Ontario and McMasters Universities Arthritis Index (WOMAC) Pain Subscale — -2.1; -0.1 units on a scale
N/A N=144 Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis
Osteoarthritis
Primary: Change of the Total WOMAC Score (WOMAC-T) — -624.12; -444.82; -605.61; -426.31 score on a scale — p=0.00030
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
Phase 1 N=6 ADSC Injections for Pain Management of Osteoarthritis in the Human Knee Joint
Osteoarthritis of the Knee
Primary: Safety as Measured by Adverse Events — 0 percentage of participants
Phase 2 N=24 Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Anterior Cruciate Ligament Tear · Anterior Cruciate Ligament Rupture
Primary: Change in Synovial Interleukin (IL) -1 Receptor Antagonist Concentration — 13.8; 16; 9.9; 7.5 pg/ml
Phase 2 N=10 The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study
Cystinuria
Primary: 24hr Urine Measurements of the Effect of SGLT-2 Inhibitor Therapy on Cystine Production in Urine in Patients With Cystinuria — 999.3 24hr urine cystine concentration…