30 closest matches · ranked by relevance
Fatty Liver, Nonalcoholic · Diabetes Mellitus, Type 2
Primary: Action on Suspected Advanced Liver Fibrosis — 55; 4 Participants
Nonalcoholic Steatohepatitis
Primary: Liver Histology (Kleiner's et al Criteria, Hepatology 2005) — 7; 13; 24 Participants
Non-alcoholic Fatty Liver Disease
Primary: Hepatic Insulin Sensitivity Index (HISI) — 0.8; 1.4 [10000/(μmol/min)x(mU/L)] — p=<0.019
Type 2 Diabetes · Obesity
Primary: Insulin Sensitivity — 8 m value — p=<0.05
Diabetes Mellitus, Type II
Primary: Percent Change in Plasma Triglycerides — -2.0; 16.0; -5.0; -5.0 percent change
Nonalcoholic Fatty Liver Disease (NAFLD)
Primary: Change in Intrahepatic Lipid Content Between Baseline and 6 Months as Measured by 1H-magnetic Resonance Spectroscopy (1H-MRS). Endpoints Were Assessed at Baseline and 6…
Nonalcoholic Fatty Liver Disease (NAFLD) · Type 2 Diabetes (T2DM)
Primary: Change in Intrahepatic Triglycerides (IHTG) Quantified by Proton Magnetic Resonance and Spectroscopy (¹H-MRS) — -8.7; -3.0 percentage decrease from baseline
Non-Alcoholic Fatty Liver Disease · Obesity
Primary: Change in Hepatic Steatosis — -2.25; -1.3; -5.48; -0.17 liver fat percentage
Nonalcoholic Fatty Liver Disease · Type 2 Diabetes Mellitus
Primary: Hepatic Steatosis — 4.0 Percentage of liver fat
Non-alcoholic Fatty Liver Disease
Primary: Percentage Change in Liver Fat Relative to Baseline Assessed by MRI-PDFF — 13.9; 8.4 percentage change in liver fat — p=0.585
Nonalcoholic Steatohepatitis (NASH)
Primary: Number of Participants With Treatment-related Adverse Events. — 3 Participants
Non-alcoholic Steatohepatitis
Primary: Percent Change From Baseline in Whole Liver Fat at Week 16 — -3.21; -16.12; -4.36 Percent change — p=0.0696
Non-Alcoholic Fatty Liver Disease
Primary: Change in Liver Fat — -3.8; -6.0 percentage of liver fat — p==0.05
Non-Alcoholic Fatty Liver Disease
Primary: Percentage of Liver Fat — -7.9; -4.6 percentage of liver fat — p=0.48
Diabetes Mellitus, Type II · Fatty Liver
Primary: Insulin Resistance and Glucose Homeostasis — .69; .24; -0.51; .73 mg/kg/min — p=0.040
Fatty Liver
Primary: Number of Participants With Sustained Reduction in Alanine Aminotransferase (ALT) to Either 50% of Baseline Value or < 40 IU/L — 9; 15; 10 participants — p=0.26
Non-Alcoholic Fatty Liver Disease
Primary: Participants With Normalized Liver Enzyme Levels — 0; 0 Participants
NAFLD · Diabetes Mellitus
Primary: Feasibility as Measured by Recruitment Rate — 8; 2 Participants
Type 2 Diabetes
Primary: Hepatic Steatosis — 6.7; NA; 8.4; 5.9 percentage of liver fat — p=0.03
Non-Alcoholic Steatohepatitis (NASH)
Primary: Percentage of Responders With Disappearance of Steatohepatitis Without Worsening of Fibrosis (ie, Participants no Longer Meeting the Criteria for Steatohepatitis) — 21…
Non-Alcoholic Fatty Liver Disease
Primary: Serum Markers (sfG) to Follow the Evolution of Liver Damage — 22.59; 28.51; 38.59; 21.34 U/L
Nonalcoholic Steatohepatitis · Nonalcoholic Fatty Liver Disease · Type 2 Diabetes Mellitus
Primary: Liver Histology (Using Kleiner et al Criteria, Hepatology 2005) — 9; 29 Participants
Type 2 Diabetes · Hypertension
Primary: Changes in Systolic Blood Pressure During Initial Intralipid Infusion — 23; 13 mmHg
Non-Alcoholic Fatty Liver Disease · Obesity · Obesity, Abdominal
Primary: Liver Fat Content — -5.3; 3.6 percent change in hepatic fat fraction
NAFLD · Nonalcoholic Fatty Liver · NASH - Nonalcoholic Steatohepatitis
Primary: Intrahepatic Lipid Content (IHL, Percent Liver Fat) — 3.9 absolute change in percentage liver fat — p=0.4
Nonalcoholic Fatty Liver · Nonalcoholic Steatohepatitis
Primary: Absolute Change in Intrahepatic Lipid Content, by 1H-MRS — -6.6; 3.6 Mean absolute percentage change
Fatty Liver
Primary: Number of Participants With Improvement of >= 2 Points in NAFLD Activity Score (NAS) — 8; 9 Participants
Intermittent Fasting · Metabolic Dysfunction-Associated Fatty Liver Disease
Primary: Transient Elastography-Controlled Attenuation Parameter — 319.5; 343.5; 291.5; 285.0 db/m
Nonalcoholic Fatty Liver Disease · Nonalcoholic Steatohepatitis
Primary: Percent Change From Baseline in Liver Fat by Magnetic Resonance Imaging-Proton Density Fat Fraction (MRI- PDFF) at Week 16 — -7.2; -17.1; -49.9; -55.9 Percent change
Hepatitis
Primary: Change in the Histological NASH Activity Index at 48 Weeks Compared With Baseline (Number of Participants in Each Change Category) — 9; 11; 5; 1 participants — p=<0.001