Clinical Trial Search

Primary: Temporary Threshold Shift Measurement by Pure Tone Audiometry (A Total of Four Hearing Assessments Were Completed for Each Formulation Period on the 1st Day Pre- and…

Primary: Change in Temporary Threshold Shift at 4 kHz--Intent To Treat (ITT) Population — 3.23; 1.32; 3.81; 4.07 dbHL — p=<0.05

Primary: PTA (EF) — 7.06; 8.94; 7.94; 12.19 dB HL — p=< 0.0005

Primary: Average Threshold Shift at 4 kHz in Both Ears — 3.94; 3.4; 2.77; 2.03 decibels — p=0.58

Primary: Reduction in Dangerous Listening Behaviour Defined as Weekly Personal Noise Exposure in dB (LEPD) — 71; 87; 84; 79 Decibels per week

Primary: Hearing Handicap Inventory for Adults (HHIA) — 26.20; 37.34; 19.21 Scale score — p=.05

Primary: Change in Connected Speech Test (CST) Score — 3.87; -5.84; -9.60 percent-correct words

Primary: Number of Blast-exposed Veterans With Abnormal Abilities in One or More Behavioral Tests of Central Auditory Processing — 99.1; 95.2; 96.6; 97.5 units on a scale

Primary: Tinnitus Functional Index Change — 53.31; 44.10; 64.93 units on a scale

Primary: Change From Adaptive Behavior Assessment System, Third Edition Score (ABAS-3) Score — 71.00; 72.00; 73.83 score on a scale

Primary: Standard Hearing Test — 422; 107; 24; 4 participants

Primary: Change in Tinnitus Functional Index (TFI) — -10.7; -10.9 units on a scale — p=<0.01

Primary: Change in TFI (Tinnitus Functional Index) After Treatment or Sham Compared to Baseline — -10.08; -5.40; 0.95; -4.34 units on a scale — p=<0.05

Primary: Change in Tinnitus Questionnaire (TQ) From Baseline to 3, 6, 12, and 18 Months — -17.8; -15.4; -11.5; -22.0 units on a scale — p=0.47

Primary: Hearing Aid Benefit as Measured by the Glasgow Hearing Aid Benefit Profile (GHABP) — 3.68; 3.55; 3.63 score on a scale

Primary: Audiological Test Results — 10.8; 6.6 decibels Hearing Level

Primary: Experimental Middle Ear Test: Ambient Wideband Absorbance — 0.39; 0.38; 0.32 Ratio

Primary: Mean Auditory Hallucination Rating Scale (AHRS) Score — 25.00; 23.17; 23.40; 19.00 score on a scale — p=0.66

Primary: Percentage of Participants With Auditory Abnormalities at Day 7 Assessed by Auditory Brainstem Response (ABR) Wave III Latency Changes on Day 7(a Type of Hearing Test)…

Primary: Quick Speech in Noise Test (QuickSIN) — 6.2; 9.6; 5.2; 10 decibels (dB) — p=>.05

Primary: Change in Objective Tinnitus Loudness — -6.1; -9.5; -10.2; -11.0 decibels sensation level (dB SL)

Primary: Ability to Understand Speech in Noise Background — 84; 78; 47 Percent correct of 100 presented words

Primary: Tinnitus Functional Index Evaluation (TFI) — 35.6; 32; 44.8; 36.2 units on a scale

Primary: Proportional Change From Baseline in Auditory Hallucination Rating Scale (AHRS) Score — 0.85; 0.94; 0.91; 0.84 proportion to baseline — p=0.47

Primary: Words-in-Noise Test (WIN) Change — 9.8; 9.9; 9.7; 10.4 dB SNR

Primary: Brain Speed Test — -0.09 z-score

Primary: Aided Thresholds Fusion-unaided PTA — 29.6 dB

Primary: Competence Score From the Psychosocial Impact of Assistive Devices Scale (PIADS) — 0.56; .37; .62; .41 units on a scale — p=0.527

Primary: Change From Baseline on the Analogue Rating of Tinnitus Awareness. — -4.08; -4.70; -9.82; -9.89 units on a scale — p=.04

Primary: Change in Short Term Relief of Tinnitus as Measured by the Tinnitus Handicap Inventory — -31 score on a scale