Phase 4 N=30 Emervel for the Correction of Lower Face Wrinkles & Folds
Nasolabial Folds · Marionette Lines · Wrinkles
Primary: Number of Subjects With Naturalness of Expression in Motion (2D Video) — 30 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=20 Study of Restylane and Perlane in the Correction of Peri-Oral Wrinkles
Peri-oral Wrinkles
Primary: Local and Systemic Adverse Events — 100 percentage of participants
N/A N=62 Princess® VOLUME Lidocaine for the Correction of Nasolabial Folds
Nasolabial Fold, Hypoplastic
Primary: NLF-SRS Grade of Nasolabial Folds Change — -1.50 score on a scale
Phase 4 N=32 Juvederm Ultra With Lidocaine Compared With Restylane for the Correction of Nasolabial Folds
Nasolabial Folds
Primary: Procedural Pain Score — 2.0; 4.1 units on a scale
Phase 4 N=45 Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines
Skin Aging
Primary: The First Visit Onset of Efficacy as Measured by Physician Assessment — 2.2 Number of Days
N/A N=60 Safety & Tolerability Study That Compares Restylane to Restylane With Lidocaine While Correcting Wrinkles in the Nasolabial Folds
Nasolabial Folds
Primary: Treatment Difference in Pain as Measured by a Visual Analogue Scale — 44.9; 14.7 Scores on a VAS Scale
N/A N=270 Effectiveness and Safety of Princess FILLER Lidocaine in Correction of Nasolabial Folds (NLF)
Dermatological Non-Disease
Primary: Responder Status Based on Independent Evaluating Investigator Live Assessment at Week 24 - Full Analysis Dataset — 222; 221 Participants — p=<0.0001
Phase 4 N=154 Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds
Wrinkles
Primary: Efficacy — 77; 74; 73; 72 participantes rated improved and higher
Phase 4 N=50 Botox Cosmetic and the Young Patient With Glabellar Furrows
Glabellar Furrows
Primary: Reduction of the Facial Wrinkle Scale — 1.86; 2.10 units on a scale — p=<.001
Phase 3 N=42 Cryo-Touch II for the Treatment of Wrinkles
Facial Wrinkles
Primary: Number of Participants With Effectiveness and Safety Success — 30; 41 participants
Phase 2 N=145 Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds
Facial Wrinkles
Primary: Change in Wrinkle Severity Rating Scale — -0.94; -1.07 units on scale
N/A N=30 An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
Wrinkles in Decolletage
Primary: Percentage of Responders on the Galderma Décolletage Scale (GDS), as Assessed Live by the Treating Investigator, at Month 9 — 93.8; 78.6 percentage of Participants
N/A N=58 Clinical Study to Evaluate the Correction of Wrinkles and Folds and Safety of YVOIRE Classic Versus Restylane in Nasolabial Fold Intradermal Injection
Temporary Correction of Wrinkles
Primary: Average of Wrinkle Severity Rating Scale (WSRS) Score Evaluated by the Evaluating Investigator at Week 26 (Visit 7) After the Final Treatment With the Investigational…
Phase 4 N=101 Prospective Evaluation of Facial Cosmetic Procedures
Cosmetic Techniques
Primary: Patient Satisfaction With Validated FACE-Q Aesthetics Survey — 28.0; 24.0; 36.0; 36.0 score on a scale
N/A N=60 Post Market Study Evaluating Princess Filler Lidocaine for the Correction of Nasolabial Folds
Correction of Nasolabial Folds
Primary: Change From Baseline in Average Nasolabial Folds-Severity Rating Scale (NLF-SRS) Grade Based on Investigator Assessment at Week 24 — -1.8 score on a scale
Phase 4 N=250 The Treatment of Glabellar Frown Lines
Glabellar Frown Lines
Primary: Efficacy, Measured as the Percentage of Participants Who Responded to Treatment — 95.7; 99.2 percentage of participants
N/A N=80 A Prospective, Open Label Study Evaluating JUVÉDERM® VOLBELLA With Lidocaine Treatment for the Correction of Skin Depressions in the Infra-orbital Area
Infra-orbital Skin Depressions
Primary: Percentage of Subjects With a ≥1 Grade Improvement From Baseline in Infra-Orbital Area on the Allergan Infra-Orbital Rating Scale (AIRS) on the Right and Left Side — 99…
Phase 3 N=121 Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
Skin Aging
Primary: Treatment Success — 89.08 % of participants
N/A N=170 Emervel Classic Lidocaine Versus Juvederm® Ultra in Treatment of Moderate to Severe Facial Wrinkles and Folds
Skin Wrinkling
Primary: Mean Change From Baseline in Wrinkle Severity Rating Scale (WSRS) at Week 24 After Final Initial Injection — -1.1; -1.2 Score on a scale
N/A N=110 Saypha® Volume LIdocaine in Nasolabial Folds
Moderate to Severe Nasolabial Folds
Primary: Responder Rate in Reduction of Nasolabial Folds — 34; 39; 73 Participants
N/A N=147 TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines, and Juvéderm® Ultra XC for the Correction of Nasolabial Folds
Nasolabial Folds, Wrinkles
Primary: Non-inferiority of the Delta of TEOSYAL® RHA GA and TEOSYAL® RHA DL Versus Juvéderm® Ultra XC for the Correction of Moderate to Severe NLFs Based on the Wrinkle Severity…
N/A N=149 Safety and Effectiveness of Sculptra Aesthetic for Correction of Cheek Wrinkles
Cheek Wrinkles
Primary: Responder Rate Based on the Blinded Evaluator's Live Assessment of the Galderma Cheek Wrinkles Scale (GCWS) at Rest at Month 12 — 26.1; 71.6 percentage of participants…
N/A N=143 Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area
Cosmetic Techniques
Primary: the Change in Dynamic Strain in the Glabella Area After Injection Over Time — 6.4; 10.9; 6.6; 8.9 percent difference of neutral+dyanamic
Phase 3 N=26 Lateral Canthal Rhytides With Medium Depth Chemical Peel With or Without Pretreatment With Botulinum Toxin A
Wrinkles
Primary: Posttreament Results of Chemical Peel if Botox A is Added as Pre-treatment — 1; 2 Units on a wrinkle severity scale — p=.002
N/A N=60 Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Nasolabial Folds
Primary: Treatment Difference in VAS (Perlane Side - Perlane-L Side) With Difference in VAS >= 10 mm — 95 Participants
N/A N=148 Restylane Defyne for Correction of Chin Retrusion
Chin Retrusion
Primary: Percentage of Participants (Responders) With At Least 1-Point Improvement From Baseline on the GCRS, as Assessed by the Blinded Evaluator at Month 6 ([Baseline…
N/A N=152 Evaluation of the Effectiveness and Safety of Diluted RADIESSE® in the Treatment of Décolleté Wrinkles
Décolleté Wrinkles
Primary: Percentage of Responders on Merz Aesthetic Scale (MAS) Décolleté Wrinkles - at Rest at Week 24 — 71.2; 6.3 percentage of subjects
N/A N=175 Restylane Defyne Compared to Restylane for Correction of Moderate to Severe Nasolabial Folds
Nasolabial Folds in Chinese Population
Primary: Percentage of Responders, Defined by at Least 1-point Improvement From Baseline on the WSRS. — 72.9; 72.8 percentage of subjects
N/A N=20 A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds
Nasolabial Fold · Safety
Primary: Response Rate in Treatment of Nasolabial Fold (NLF) Based on a Scale — 63.2; 68.4 percentage of participants
N/A N=205 Sculptra for Correction of Midface Volume Deficit and/or Midface Contour Deficiency
Midface Volume Deficit
Primary: Percentage of Participants With 1 Point Improvement From Baseline on the Medicis Midface Volume Scale (MMVS) as Measured by the Blinded Evaluator at Month 12 — 68.8…