N/A N=65 Exercise in Burn Survivors: Cooling Modalities
Burn Injury
Primary: Change in Core Temperature (°C) During Control Intervention — .578; .920; .622; .885 °C
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.
Wound Healing
Primary: Number of Participants With Wound Healing — 10 participants
Phase 3 N=175 A Study to Evaluate the Efficacy and Safety of NexoBrid in Subjects With Thermal Burns
Thermal Burns
Primary: Primary Endpoint: Number of Participants With Complete Eschar Removal. — 70; 1 Participants — p=<0.0001
Phase 3 N=71 StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
Burn, Thermal
Primary: Percent Area of Treatment Sites Requiring Autografting by Month 3 — 4.33; 102.10 percentage of treatment sites — p=<0.0001
Phase 1 N=30 StrataGraft® Skin Tissue as an Alternative to Autografting Deep Partial-Thickness Burns
Skin Wound · Burns · Trauma-related Wound
Primary: Number of Participants With Wound Closure of the Treatment Sites at Three Months — 29; 29 Participants
N/A N=45 A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns
Burns · Wound Healing
Primary: Number of Subjects Healed at Day 14. — 35 participants
Phase 4 N=20 Comparison of Wound Bed Establishment in Facial Burns
Burns
Primary: Time to Wound Epithelialization — 37.4; 37.6 days — p=.0853
N/A N=14 Assessment of Safety and Effectiveness of Biodegradable Temporizing Matrix in the Treatment of Deep Burn Skin Injuries
Burns
Primary: BTM 'Take' Rate — 95.22 percentage of BTM take per subject
Phase 3 N=145 A Study to Evaluate the Efficacy and Safety of NexoBrid in Children With Thermal Burns Compared the Standard of Care
Thermal Burns
Primary: Time to Complete Eschar Removal (in Days) — 0.99; 5.99 Days — p=0.0008
Phase 3 N=40 Laparoscopic Cholecystectomy And Capacitive Coupling - Coag Versus Blend Mode Causing Thermal Injury at Port Site Skin
Intraoperative Complications · Thermal Injury · Electrocoagulation
Primary: Histologic Thermal Injury to Epigastric Port Site Skin — 1; 7 participants
N/A N=30 ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Number of Participants With Confirmed Treatment Area Closure of RECELL-treated Wounds Compared to Control (Non-inferiority) — 24; 22; 2; 4 Participants
Early Phase 1 N=4 Application of the Apsara Thermal Wand System
Tightening of Skin Laxity
Primary: Serious Adverse Events — 0 Number of Serious Adverse Events
N/A N=15 Evaluation of Antimicrobial Soft Silicone, Silver Containing, Foam Dressing, Mepilex Border Ag, in Second Degree Burns
Burns
Primary: Evaluate the Experience of Using Mepilex Border Ag ( a Silver Dressing) in Normal Clinical Practice — 9 burns healed
Phase 4 N=36 Continuous Lidocaine Infusion for Management of Perioperative Burn Pain
Thermal Burns
Primary: Narcotic Consumption (Measured in mg/kg Narcotic Consumption) — 57.5; 67.75 mg/kg narcotic consumption
N/A N=21 Body Temperature in Persons With Tetraplegia When Exposed to Heat
Spinal Cord Injury
Primary: Core Body Temperature — 2.04; -0.05 Percent Change — p=0.0001
N/A N=17 Chronic Passive Heating in Individuals With T2DM
Type2 Diabetes
Primary: Insulin Sensitivity — 0.31; 0.33; 0.10; 0.10 AU
N/A N=18 Fractional Ablative Laser Treatment for Skin Grafts
Burn Scar · Skin Graft Scar
Primary: Contracture of Scar Surface Area (Percentage of Original Area) — 97; 97 percentage
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
Phase 4 N=15 Effect of Topical Application of Iodex® Balm on Local Surface Temperature
Pain
Primary: Time to Significant Increase in Local Surface Temperature
N/A N=54 Effectiveness of Pressure Garment Therapy After Burns
Hypertrophic Scarring After Burn Injury
Primary: Pressure Under Compression Garment — 25; 6.4 mm Hg
N/A N=101 A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries
Burns
Primary: Incidence of RECELL-treated Area Closure Compared to Control at 4 Weeks (Non-inferiority) — 82; 87; 82; 83 Participants
N/A N=3 Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing
Burns
Primary: Perfusion of Burned Area — 200; 100; 205; 180 % perfusion compared to normal skin
N/A N=20 Radiofrequency Hyperthermia Safety Study
Chronic Pain · Soft Tissue Injuries · Wound Heal
Primary: Mean Temperature Change- Skin Evaluation on Leg With Device — 6.21 degrees
N/A N=20 Analysis of Human Tissue Temperature After Application of Therapeutic Modalities.
Humans · Young Adult · Health
Primary: The Most Effective Capacitance Shortwave Technique in Relation to Temperature Increase and Heat Conservation Measured by Infrared Thermography — 1.72; 0.58; 0.94; 7.9…
N/A N=29 Fractionated Carbon Dioxide Laser and Burn Scar Contractures: Evaluation of Post-Treatment Scar Function and Appearance
Burn Scars
Primary: Scar Pigmentation, Baseline vs 15-months — 50.93; 49.59 units on a scale
N/A N=15 A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
Spinal Cord Injuries
Primary: Skin Temperature (Tsk) Change — -5.6; -6.9; 2.1 Degrees Celsius — p=0.002
N/A N=24 Evaluation of Post-Exposure Sauna Treatment of Firefighters - A Pilot Study
Post-fire Rehabilitation of Firefighters in Sauna
Primary: Urinary Excretion of Hydroxylated PAHs (PAH-OHs) — 10364.2; 40012.1; 6964.1; 22604.3 ng/L — p=0.0000009
Phase 2 N=20 Cranial Electrotherapy Stimulation in Burned Patients
Post Traumatic Stress Disorders · Burns
Primary: Mean Post-Traumatic Stress Questionnaire-Military (PCL-M) Score — 53.8; 56.7; 48.8; 50.4 Score
N/A N=30 Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin Lesion Effects
Histological Response of Tissue to Cold
Primary: Biological Tissue Response
Phase 1 N=59 Cumulative Irritation Potential of 828 Ointment
Healthy Volunteers
Primary: Presence of Cumulative Irritation — 163.0; 109.0; 2073.0 units on a scale