N/A N=30 Diagnostic Device for the Assessment of Pulpal Blood Flow
Dental Pulp Test
Primary: Subjective Tooth Assessment: Number of Teeth With Normal and Abnormal Pulp — 111; 32 Teeth
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=169 Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Caries · Dental Pulp Exposure
Primary: Parameters Evaluated After Treatment — 19; 19; 25; 3 Participants
N/A N=4 Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Dental Pulp Diseases · Dental Pulp Necrosis · Nerve Root Pain Nec
Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)
N/A N=98 Clinical Comparison of Vital Pulp Capping Restorative Protocols
Deep Dental Caries
Primary: Success Rate Based on Pulp Vitality Tests (Vital/Non Vital) — 96.2; 100; 100; 86 Percentage of success rate — p=>0.1
N/A N=60 Survival of Endocrowns Made From Different Ceramics
Pulp Disease, Dental · Dental Caries · Dental Leakage
Primary: Survival of Dental Prosthesis — 19; 14; 17 Teeth
Phase 2 N=24 Use of Mineral Trioxide Aggregate in the Treatment of Traumatized Teeth
Periapical Diseases
Primary: Changes Between Initial and Post Treatment Dimensions of Periapical Lesions — 37.34; 34.04; 16.20; 17.54 square millimeters — p=<0.01
Phase 4 N=64 Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Pulpitis - Irreversible
Primary: Clinical Success at 6 Months — 27; 30 Participants
Phase 4 N=60 Theracal Pulpotomy in Primary Molars
Deep Caries
Primary: Clinical Examination — 30; 30 Participants
N/A N=36 The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth
Pulpal Necrosis
Primary: Vitality of Teeth (Units) Using Thermal and Percussion Sensitivity Trend Observed During Study Duration (3-11 Months) — .559; .592; .065; .040 Teeth
N/A N=43 Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 27.19; 24.08 percentage
N/A N=36 Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
Periapical Periodontitis
Primary: Number of Participats Showing Efficacy (Functionality) — 18; 18 Participants
N/A N=36 In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
Cavity · Cavities of Teeth
Primary: Marginal Staining: World Dental Federation (FDI) Criteria - Baseline — 18; 18; 0; 0 Participants
N/A N=194 Post-endodontic Pain Survey
Postoperative Pain · Endodontic Disease · Obturation
Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale
N/A N=17 Retrospective Clinical Evaluation of Nano-hybrid-composite Denture Teeth
Edentulous Mouth · Dental Prosthesis Failure
Primary: Survival Rate of Dentures With SR Phonares II Teeth — 17 Participants
N/A N=76 Clinical Trial NuSmile Crowns
Primary Dental Caries, Multisurface Origin (Diagnosis)
Primary: Fitting — 37; 42; 48; 3 Teeth
Phase 2 N=70 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial
Dental Caries · Dental Pulp Exposure
Primary: Comparison of MTA/FS Pulpotomy Versus RCT Treated Incisors With Acceptable Radiographic Outcome at 12 Months Post-procedure. — .97; .92 Proportion of incisors — p=.15
Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Phase 4 N=41 EMD and/or Bone Substitute for the Treatment of Class II Furcations
Periodontal Disease
Primary: Relative Horizontal Clinical Attachment Level (RHCAL) at 12 Months — 2.31; 3.00; 2.57 mm
N/A N=100 Effect of Buffered Numbing Solution on Patients With Toothaches
Irreversible Pulpitis (Toothache)
Primary: Percent of Patients With Successful Anesthesia (% of Patients Able to Have Treatment Without Additional Anesthesia) — 16; 20 Participants
N/A N=44 Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 31.27; 36.21 % vital bone
Phase 4 N=90 A Clinical Study Assessing the Effects of a Marketed Dentifrice on Tooth Sensitivity While Undergoing Tooth Bleaching
Dentin Sensitivity
Primary: Visual Analogue Scale (VAS) Scores of the Tooth Sensitivity Questionnaire Collected Through the Study — 33.8; 41.6; 36.9; 31.1 millimeter
N/A N=120 Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
Dental Atraumatic Restorative Treatment
Primary: Enamel Hardness — 348.4; 351.6; 354.5 Vickers hardness kg f/mm2 — p=0.231
N/A N=69 Sonendo GentleWave™ System for Treatment in Molar Teeth Requiring Root Canal Therapy
Root Canal Therapy
Primary: Number of Participants With a PAI Score of < 3, = 3, or = 4 or 5 — 51; 3; 0 Participants
N/A N=102 Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft
Dental Extraction · Wound Heal
Primary: Percentage Vital Bone Formation — 37.33; 40.76; 24.46; 23.85 percentage of vital bone formation
N/A N=101 Evaluation of Hyaluronic Acid Pulpotomies in Primary Molars
Pulpitis
Primary: Number of Teeth Sensitive to Percussion in 3 Groups — 7; 6; 3 teeth — p=>0.05
N/A N=24 A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
Tooth Extraction
Primary: Change in Buccal Plate Thickness From Baseline to Month 6 — 1.85; 1.25 mm — p=0.11
N/A N=44 Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft
Tooth Extraction
Primary: Percent New Vital Bone Formation — 24.7; 36.2 percentage of vital bone
Phase 4 N=40 Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Primary: VAS Scores as Measures of Profoundness of Pulpal Anesthesia — 3.1; 1.2 Score on a scale
N/A N=32 Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis
Postoperative Pain
Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale
Phase 4 N=108 Combined Bleaching Technique: Efficacy and Tooth Sensitivity
Tooth Bleaching · Tooth Sensitivity
Primary: Tooth Sensitivity (TS) — 1; 1; 1; 0 score on a scale