Clinical Trial Search

Primary: Total Net D12FS Caries Increment (Total of Non-cavitated Lesions (D1), Cavitated Lesions (D2) and Sound Surfaces (S)) — 2.43; 2.68 weighted increment units/13 months…

Primary: Change in Oral Plaque — -1.05; -0.03 log(percentage) — p=0.001

Primary: Percentage of Participants With Tooth Loss Over 16 Year Period — 16.4; 13.8; 22.1; 16.9 percentage of participants

Primary: Sost Values for 6th Month — 1389.177; 1085.405; 1596.585; 2131.87 ng/ml — p=<0.01

Primary: Bleeding on Probing (BOP) — 14.5; 12.3 percentage of sites

Primary: Number of Participants With Arrested Dental Caries, Assessed Using a Clinical Oral Examination — 48; 53 Participants

Primary: Gingival Index (GI) — 1.04; 1.01 units on a scale — p=<0.05

Primary: Proportion of Subjects With All Caries Arrested — 108; 101 Participants

Primary: Radiographic Bone Level — 2.69; 2.54 mm

Primary: Percentage of Participants Who Indicate Surgical Intervention — 74 percentage of the dentists

Primary: Dental Plaque Levels Measures on Scale of 0-2 — 0.391 units on a scale

Primary: Microbial Levels — 11; 7; 15; 15 Participants — p=0.35

Primary: Change From Baseline Gingivitis at Day 14 as Measured by Non-invasive Microimaging and Gingival Index. — 0.6; 0.15 units on a scale

Primary: Plaque Index — 1.07; 1.19; 1.31; 1.11 units on a scale — p=0.1561

Primary: Number of Bleeding Sites at Week 12 — 42.02; 67.36 number of bleeding sites — p=<0.0001

Primary: Gingival Margin Plaque Index — 15.4; 12.81 Units on a scale — p=0.05

Primary: Marginal Staining: World Dental Federation (FDI) Criteria - Baseline — 18; 18; 0; 0 Participants

Primary: Dental Plaque — 2.273; 1.806; 2.041 Units on a scale — p=<0.05

Primary: Fluoride Concentration in Dental Biofilm Fluid at Baseline — 0.24; 0.22 parts per million (ppm) of fluoride — p=0.8412

Primary: Metabolite Associated With Inflammation (Cadaverine) — 1.119186; 0.92077 ion count — p=<0.05

Primary: Number of New Tooth Root Caries Lesions — 1.1; 0.43; 0.56 new carious root surfaces

Primary: Whole-mouth Mean Modified Gingival Index (MGI) Score at Day 42 — 1.880; 1.770 Unit on a scale

Primary: Knowledge Score — 11; 13; 11; 13 score on a scale — p=0.001

Primary: Dental Plaque Index — 2.48; 2.42 Units on a scale — p=0.05

Primary: Gingival Health — 0.46; 0.18 units on a scale — p=0.015

Primary: Residual Protein Concentration — 33.5; 28; 20.4; 20.2 ug/mL

Primary: Plaque Index — 0.91; 0.84; 1.77 Units on a scale — p=0.05

Primary: Number of Participants Completing Study Protocol — 17; 34; 14; 30 Participants

Primary: Percentage Surface Microhardness Recovery of Test Dentifrices Relative to Placebo Dentifrice — 30.72; 29.49; 28.29; 25.13 %SMHR — p=<0.0001

Primary: Caries Activity and Progression Assessment Using LASER Fluorescence Readings by Diagnodent® Device. — 18.6; 1.1 units on a scale