N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=10 Biomechanical Assessment of Gait in Lower-Extremity-Amputees
Prosthesis User
Primary: Overall Asymmetry Index — 0.064; 0.352; 0.541; 1.481 unit-less index (0 = perfect symmetry)
N/A N=6 Basic Mobility and Balance Performance of Low Active Transfemoral Prosthesis Users With a Powered Prosthetic Knee
Prosthesis User · Amputation
Primary: Timed Up and Go Test (TUG Test) — 13.3; 16.8 seconds
N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
N/A N=12 Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Amputation
Primary: Mechanical Crank Power Output — 0.59; 0.99; 0.60; 0.97 W/kg
N/A N=11 Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation
Lower Extremity Amputation
Primary: Peak Transverse-plane Prosthetic Socket Torque Normalized to Body Mass — 0.299; 0.340; 0.306; 0.292 Nm/kg — p=0.029
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=11 Prosthetic Components and Stability in Amputee Gait
Diabetes Mellitus · Leg Injuries · Traumatic Amputation
Primary: Local Dynamic Stability (Hip During Straight Walking) — .74; .74 dimensionless — p=>0.99
N/A N=6 Biomechanical Evaluation of a Novel, Compliant Low Profile Prosthetic Foot
Amputation
Primary: Total Energy Stored (TES) — 20.1; 13.3 Joules
Phase 3 N=10 Southern Bone & Joint Study - Brimless Sockets
Socket Designs of Transfemoral Amputees.
Primary: Gait
N/A N=68 Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees
Transtibial Amputee
Primary: Number of Participants With Significant Increases in Socket Comfort Score (SCS) — 5; 6; 4 participants
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
N/A N=20 Functional Electrical Stimulation Use in Trans-tibial Amputations
Traumatic Amputation of Lower Extremity
Primary: Change in Knee Extension Isometric Strength (Peak Torque) Using the Biodex Measurement System — -0.1; 2.2 Nm/kg — p=0.768
N/A N=31 Community Walking Trials: Comparing Prosthetic Feet
Lower Extremity Amputation
Primary: Difference Between Investigational Foot and Usual Foot in the Prosthetic Evaluation Questionnaire (PEQ): Ambulation Sub-Scale — 4.2 score on a scale — p=0.092
N/A N=12 Reducing Asymmetry During Gait Using the TPAD (Tethered Pelvic Assist Device) for Stroke Patients
Stroke
Primary: Force Symmetry Ratio During Gait — 0.71; 0.83 ratio
N/A N=111 Unipolar vs. Bipolar Hemostasis in Total Knee Arthroplasty: A Prospective Randomized Trial
Knee Arthroplasty
Primary: Drain Output. — 776; 778 mL
N/A N=45 The Assessment of Patient Specific Instrumentation for Unicompartmental Knee Replacement
Knee Arthritis
Primary: Radiological Assessment of Component Positioning — 0.9; 1.8; 9.1; 8.8 Degrees — p=<0.05
Phase 4 N=52 Contralateral ReSTOR / Monofocal or Phakic Eye
Cataracts
Primary: Visual Acuity — -0.04; -0.01; 0.14; 0.18 LogMar
N/A N=30 What is the Optimal Stiffness and Height of a Running-specific Prosthesis?
Amputation, Traumatic · Traumatic Amputation of Lower Extremity · Wounds and Injuries
Primary: Biomechanics — 0.1386; 0.1835 N/kg
N/A N=14 Spring Loaded Tri-Compartment Unloader Knee Brace Study
Anterior Knee Pain
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 61.91; 72.59; 71.17; 85.99 score on a scale
N/A N=10 Intent Recognition for Prosthesis Control
Amputation
Primary: Overground Self-selected Walking Speed — 0.695 Meters per second
N/A N=36 Evaluation of a Modified Running-specific Prosthetic Foot
Transtibial Amputation
Primary: Metabolic Oxygen Consumption (VO2), Participants With Unilateral Amputation — 1041.1; 1077.4; 1210.9; 1253.5 ml/min — p=.18
N/A N=23 Falls in Older Persons With Limb Loss
Amputation · Elderly
Primary: Foot's Height During the Swing Phase of Walking (i.e., Foot Clearance) Measured in Centimeter — 6.1; 5.5; 6.1; 5.7 cm
N/A N=25 Comparative Outcomes Assessment of the C-Leg With a New Knee Prosthesis
Other and Unspecified Complications of Amputation Stump
Primary: 75 Meter Self Selected Walking Test — 65.1; 64.0; 54.0 seconds
N/A N=147 Self-management to Improve Function Following Amputation
Amputation, Limb Loss
Primary: Short Musculoskeletal Function Assessment (SMFA) — 32.34; 30.19 score on a scale
N/A N=5 Comparison of Prosthetic Feet for People With Syme's Amputation (XF Symes Study)
Amputation · Artificial Limb
Primary: Ratio Between Sound and Prosthetic Side Step Lengths — 0.88; 0.87; 1.02; 0.91 Sound step length / Pros. step length