N/A N=2,804 The Twin Birth Study: A Trial Comparing Planned Vaginal Birth to Elective Caesarean Section of Twins
Twin Pregnancy
Primary: Perinatal/Neonatal Mortality and/or Serious Neonatal Morbidity — 60; 52; 24; 17 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=46 Prevention of Preterm Birth With a Pessary in Twin Gestations
Premature Birth · Short Cervix
Primary: Number of Participants With Preterm Delivery — 9; 8 Participants
Phase 3 N=321 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Preterm Birth
Primary: Newborn Respiratory Distress Syndrome (RDS) — 44; 18 Twins
N/A N=5 Randomized Clinical Trial: Expectant Management vs Laser Treatment of Monochorionic Twins With Severe Selective Intrauterine Growth Retardation and Absent or Reverse Diastolic Flow in the Umbilical Artery
Intrauterine Growth Retardation
Primary: Survival — 100; 100 percentage of AGA babies who survived
Phase 4 N=66 Prophylactic Methylergonovine for Twin Cesarean
Twin; Complicating Pregnancy · Postpartum Hemorrhage
Primary: Change in Maternal Hemoglobin Level — 1.1; 2.1 g/dL
Phase 3 N=1,311 A Trial of Pessary and Progesterone for Preterm Prevention in Twin Gestation With a Short Cervix
Short Cervical Length
Primary: Number of Participants With Delivery or Fetal Loss of Either Twin Prior to 35 Weeks Gestation — 84; 84; 86 Participants
N/A N=251 Optimisation of the Management of Placental Delivery in Second Trimester Pregnancy Interruption
Placenta, Retained · Postpartum Hemorrhage
Primary: Placental Retention Rate — 26; 8; 24 participants — p=0.05
N/A N=206 Determination of Abnormal Fetal Growth or Amniotic Fluid With Third Trimester Ultrasounds in Uncomplicated Pregnancies: A Randomized Trial
Uncomplicated Pregnancy · Abnormal Fetal Growth or Fluid
Primary: Number of Participants With Fetal Growth Restriction — 2; 8 Participants
N/A N=91,084 Comparing Effectiveness of Treating Depression With & Without Comorbidity to Improve Fetal Health
Depression · Preterm Delivery
Primary: Preterm Delivery — 139; 556; 272; 569 Participants
N/A N=995 Neonatal Outcome by Reason for Delivery
Preterm Delivery
Primary: Composite Perinatal Morbidity — 277; 203; 221; 45 participants
N/A N=53 Multifactorial Approach to Emergent Cerclage
Cervical Insufficiency
Primary: Gestational Latency Achieved Between Cerclage Placement and Time of Delivery — 80; 97 days — p=0.018
N/A N=144 The Use of Progesterone to Reduce Preterm Birth
Preterm Birth
Primary: Weeks Gestation at Birth Among Patients Receiving the Active Drug. — 31.9; 30.2 weeks
N/A N=16 Acute Exercise Effects in Obese Pregnancy
Pregnancy Complications · Obesity · Pre-Eclampsia
Primary: Oral Glucose Insulin Sensitivity (OGIS) Index — 405.0; 426.0; 418.9 uU/mL
N/A N=150 Psychological Impact of Pregnancy of Unknown Location
Pregnancy of Unknown Location · Ectopic Pregnancy · Anxiety
Primary: Psychological Morbidity — 10; 10; 5; 5 score on a scale
Phase 4 N=30 Simultaneous Mifepristone and Misoprostol Versus Misoprostol Alone for Induction of Labor of Nonviable Second Trimester Pregnancy: a Pilot Randomized Controlled Trial
Abortion, Second Trimester · PPROM · Rupture, Spontaneous
Primary: Delivery Within 12 Hours — 5; 5 Participants
Phase 3 N=900 Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
Pregnancy · Unexplained Infertility
Primary: Multiple Gestation Rate Following Recruitment of Multiple Follicular Development With an AI, as Compared to CC and FSH. — 9; 8; 34 number of multiples
N/A N=360 Lifestyle and Pregnancy: The Clinical Effect of Lifestyle Intervention During Pregnancy in Obese Women
Maternal Obesity · Gestational Weight Gain · Obstetric Complications
Primary: Cesarean Section
N/A N=25 Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Pregnancy Complications
Primary: The Number of Participants Who Achieved a Hemoglobin A1C <7% — 5; 12 Participants
Phase 4 N=108 Detemir Versus NPH for Type 2 Diabetes Mellitus in Pregnancy
Diabetes Mellitus, Type 2
Primary: Number of Neonates With Composite Adverse Neonatal Outcome — 31; 35 Participants
N/A N=480 Maternal Lifestyle and Neonatal Hypoglycemia
Hyperinsulinemia · Miscarriages · Pregnancy
Primary: Neonatal Hypoglycemia — 3; 15 neonates
N/A N=103 Twinrix Pregnancy Registry
Hepatitis
Primary: Number of Outcomes From Pregnancies With Reported Exposure Within 28 Days of Last Menstrual Period — 0; 0; 0; 0 Pregnancy Outcomes
N/A N=30 Maternal Fetal Device Performance Singleton
Pregnancy
Primary: Success Rate Calculated Based on Collection of Fetal Heart Rate Data From Investigational Devices on Subjects Enrolled in Each Gestational Age Group — 85.01; 92.27…
N/A N=312 Optimizing Health From Pregnancy Through One Year Postpartum
Obesity · Pregnancy Related
Primary: Maternal Weight — 196.59; 201.03; 193.70; 201.66 pounds — p=.80
Phase 3 N=10,154 Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Preeclampsia
Primary: Composite of Pregnancy-associated Hypertension and Serious Adverse Outcomes in the Mother or Fetus or Neonate — 305; 285 Participants — p=0.42
N/A N=24 Pregnancy Intervention With a Closed-Loop System (PICLS) Study
Type 1 Diabetes Mellitus · Pregnancy in Diabetes
Primary: Number of Episodes of Severe Hypoglycemia — 0; 0 Number of Episodes
N/A N=313 Linking Inter-professional Newborn and Contraception Care
Family Planning · Contraception · PostPartum
Primary: Number of Patients Who Receive Contraception by Two Months Postpartum — 474; 339 Participants — p=0.12
Phase 3 N=800 Improving Pregnancy Outcomes With Progesterone
Pre-term Birth · HIV-1-infection
Primary: Number of Participants Experiencing Preterm Births or Stillbirths — 36; 36 Participants
N/A N=281 Maternal-Offspring Metabolics:Family Intervention Trial
Pregnancy · Weight Gain
Primary: Gestational Weight Gain (GWG) — 12; 10 kg — p=0.01
N/A N=122 Prevention of Preterm Birth With a Pessary in Singleton Gestations
Preterm Birth · Short Cervix
Primary: Number of Subjects Experiencing Preterm Birth — 26; 23 Participants
N/A N=236 Tennessee Connections for Better Birth Outcomes
Preterm Birth
Primary: Infant Gestational Age — 38.14; 38.14 weeks — p=.64