Phase 2 N=6 VIGABatrin in Post-anoxic STATus Epilepticus - Phase IIa
Status Epilepticus, Electrographic · Coma
Primary: Primary Pharmacologic Outcome - Absorption — 6; 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 The Efficacy of Familiar Voice Stimulation During Coma Recovery
Traumatic Brain Injury · Coma · Vegetative State
Primary: DOCS Neurobehavioral Measure (DOCS = Disorders of Consciousness Scale) Change — 13.5; 18.9 units on a scale — p=.465
N/A N=36 Nutritional Status and Enteral Absorption Capability After Brain Death
Brain Death
Primary: Primary Outcome Measure is IL-6 Level — 565.5; 264.9 pg/ml
Phase 2 N=62 Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Vegetative State · Minimally Conscious State · Disorders of Consciousness
Primary: Change in CRS-R Total Scores — 12.17; 10.60 units on a scale
N/A N=33 Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Respiration, Artificial · Critical Illness · Chronic Disease
Primary: Functional Assessment: Handgrip — 3.6; 1.3 kg
N/A N=108 Pivotal Study of VNS During Rehab After Stroke (VNS-REHAB)
Cerebrovascular Stroke · Upper Extremity Paresis
Primary: Fugl-Meyer Assessment, Upper Limb (FMA-UE) Average Change — 5.0; 2.4 units on a scale — p=0.0014
N/A N=211 Identifying and Facilitating Ventricular Recovery on Mechanical Support
Heart Failure
Primary: Number of Subjects With Left Ventricular Recovery and LVAD Explant — 8 Participants
N/A N=4 Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness
Traumatic Brain Injury
Primary: Intensity of Adverse Event — 0.5; 0.98; 0.33 score on a scale — p=<0.05
Phase 3 N=184 Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)
Traumatic Brain Injury
Primary: Disability Rating Scale: Functional Status — 17.3; 18.7; 17.1; 17.8 units on a scale — p=0.007
N/A N=20 Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome
Consciousness Disorders · Locked-In Syndrome
Primary: Behavioral Diagnosis of Level of Consciousness (LoC) — 0; 23; 2; 23 score on a scale