N/A N=30 Clinical Assessment of Visual Function With the Acrysof ReSTOR Multifocal IOL
Visual Acuity
Primary: Near Uncorrected Visual Acuity(UCVA — 0.5 logMAR
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=31 Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of a Lipid- Based Lubricating Eye Drop
Visual Acuity
Primary: Visual Acuity (logMAR) at 3 Minutes Post Instillation — 0.09; 0.08 LogMAR
Phase 4 N=50 Corneal and Conjunctival Sensitivity and Staining Study
Myopia · Hyperopia
Primary: Corneal Sensitivity — 26.9; 25.5 percent CO2
N/A N=51 Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure
Normal Contact Lens Wear
Primary: HRT Corneal Scan — 85; 66; 49; 63 cells/mm^3
N/A N=33 Clinical Biocompatibility Evaluation of Contact Lens Coatings
Refractive Errors · Ametropia
Primary: Average Percent Area of Solution-related Corneal Staining — 7.01; 12.82; 13.54; 7.58 percentage of area
Phase 4 N=43 Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers
Visual Acuity
Primary: Visual Acuity (logMAR) — 0.15; 0.21; 0.02; 0.05 logMAR
N/A N=40 Assessment of Visual Performance in Patients With Low Levels of Astigmatism
Cataract Extraction · Corneal Astigmatism
Primary: High and Low Contrast Acuity — 0.0855; 0.065; 0.082 logMAR
N/A N=60 Performance Assessment of a Modified Daily Disposable Contact Lens
Refractive Errors · Myopia · Hyperopia
Primary: High Contrast Distance Visual Acuity (logMAR) — -0.04; -0.04; -0.05; -0.05 logMar
N/A N=30 Safety and Efficacy of 2 Concentrations of Lubricin vs Sodium Hyaluronate in Ocular Discomfort After Refractive Surgery.
Ocular Discomfort
Primary: Changes From Baseline (Day 1 Pre-dose) in Ocular Tolerability Using a Visual Analogue Scale (VAS) — -22.8; -30.1; -20.9; -20.9 mm — p=0.3474
N/A N=60 Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear
Contact Lens-induced Corneal Fluorescein Staining
Primary: The Primary Outcome Measure Will be Corneal Epithelial Dye Diffusion Rate in Nanometers Per Second, for the Test and Control Eyes. — 0.0567; 0.0583 nanometers per second
N/A N=31 Evaluation of Binocular Visual Acuity and Refractive Stability in the Alcon Clareon Intraocular Lens
Cataract
Primary: Refractive Stability — 0.03 Diopters (D)
Phase 2 N=44 Clinical Investigation of Visual Acuity in Contact Lens Wearers After Instillation of Investigational Lubricating Eye Drops
Visual Acuity
Primary: Monocular logMAR Visual Acuity — 0.033; 0.038 logMAR
N/A N=72 Evaluation of Visual Acuity With a Reusable Toric Multifocal Contact Lens
Visual Acuity
Primary: Binocular High Luminance High Contrast logMAR Visual Acuity — -0.13; -0.02; 0.09 LogMAR
N/A N=123 Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology to Evaluate Overall Visual Acuity.
Visual Acuity
Primary: Monocular logMAR Visual Acuity — 0.051; 0.032; 0.044; 0.036 logMAR
N/A N=24 Open Eye Corneal Swelling With Daily Disposable Contact Lenses and no Lens Wear
Corneal Swelling
Primary: Percentage Change From Baseline of Corneal Swelling 8 Hours Post Fit — 0.07; -0.02; 0.14; -0.06 percentage of change from baseline
Phase 4 N=8 Study of the Presence and Extent of Corneal Disturbance Associated With B+L Biotrue MPS Used With B+L PureVision Lenses
Keratitis
Primary: Number of Participants Wiith Corneal Staining — 1; 6 participants
N/A N=26 Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients
Conjunctival Staining
Primary: Mean Circumlimbal Conjunctival Staining Score — 6.39; 5.55; 5.68 Units on a scale
Phase 4 N=50 A Single-Center Evaluation of the Anti-Inflammatory Effects of Lastacaft as Measured by In-Vivo Confocal Microscopy
Allergic Conjunctivitis
Primary: Conjunctival Inflammation at 1 Hour (+30 Minutes) Post CAC on Day 1 — 3.12; 3.02 units on a scale
N/A N=80 Visual Assessment of DAILIES® AquaComfort Plus® for Astigmatism as Compared to 1-DAY ACUVUE® MOIST® for Astigmatism
Astigmatism
Primary: High Contrast Time Controlled Visual Acuity (TCVA) at Day 10 — 0.02; 0.04 VA units
N/A N=262 Evaluation of Astigmatic Contact Lenses
Visual Acuity
Primary: Monocular Distance Visual Acuity (VA) — 258; 263 Eyes
Phase 4 N=13 Assessment of Alcon's Ocular Image Quantification System
Allergic Conjunctivitis
Primary: Change From Baseline in Patient-Assessed Ocular Itching, Environmental Exposure Chamber (EEC), at 3 Hours — -1.63; -1.11 Units on a scale
Phase 4 N=37 The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED
Dry Eye Disease
Primary: IVCM for Density of Corneal Immune Dendritiform Cells — 9.47; 28.60 cells/mm^2
Phase 4 N=13 Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients
Allergic Conjunctivitis
Primary: Patient-Assessed Ocular Itching — 2.2; 2.2; 0.5; 0.5 units on a scale
N/A N=94 Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining
Dry Eye Syndrome
Primary: Mean Change From Baseline in Total Ocular Surface Staining (TOSS) Score at Day 35 (Phase I) — -2.2; -1.7 units on a scale
Phase 4 N=70 Subjective and Objective Performance of Systane Complete Multi-Dose PF Versus Walgreen's Lubricant Balance
Dry Eye
Primary: SANDE Questionnaire — -7.2; -2.2 score
N/A N=50 Theranostic Guided Riboflavin/UV-A Corneal Cross-linking
Keratoconus
Primary: Validation of the Theranostic Scores — 91; 95 Percentage
N/A N=40 Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry Eye
Dry Eye Syndrome
Primary: Change From Baseline in Foreign Body Sensation, Burning/Stinging, Itching, Pain, Stick Feeling, Blurred Vision, Photophobia and Total Ocular Tolerability Score (VAS)…
Phase 2 N=10 A Study of the KIO-201 (Ocular Bandage Gel) for Improving Persistent Corneal Epithelial Defects
Persistent Corneal Epithelial Defect
Primary: Percentage of Patients Achieving Corneal Healing (<0.5 mm2 Lesion Size) of the Persistent Corneal Epithelial Defect at 4 Weeks — 5 Participants
N/A N=53 Clinical Evaluation of Two Cosmetic Contact Lenses
Visual Acuity
Primary: Distance Monocular logMAR Visual Acuity — -0.159; -0.157 logMAR
N/A N=57 Evaluating Visual Acuity and Initial Fit Performance of Two Soft Contact Lenses
Visual Acuity
Primary: Monocular Distance Visual Acuity (logMAR) — -0.00; -0.00 logMAR